180 related articles for article (PubMed ID: 24866741)
1. Mexiletine as a treatment for primary erythromelalgia: normalization of biophysical properties of mutant L858F NaV 1.7 sodium channels.
Cregg R; Cox JJ; Bennett DL; Wood JN; Werdehausen R
Br J Pharmacol; 2014 Oct; 171(19):4455-63. PubMed ID: 24866741
[TBL] [Abstract][Full Text] [Related]
2. Comparison of Gating Properties and Use-Dependent Block of Nav1.5 and Nav1.7 Channels by Anti-Arrhythmics Mexiletine and Lidocaine.
Wang Y; Mi J; Lu K; Lu Y; Wang K
PLoS One; 2015; 10(6):e0128653. PubMed ID: 26068619
[TBL] [Abstract][Full Text] [Related]
3. Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7.
Han C; Lampert A; Rush AM; Dib-Hajj SD; Wang X; Yang Y; Waxman SG
Mol Pain; 2007 Jan; 3():3. PubMed ID: 17239250
[TBL] [Abstract][Full Text] [Related]
4. A novel SCN9A mutation responsible for primary erythromelalgia and is resistant to the treatment of sodium channel blockers.
Wu MT; Huang PY; Yen CT; Chen CC; Lee MJ
PLoS One; 2013; 8(1):e55212. PubMed ID: 23383113
[TBL] [Abstract][Full Text] [Related]
5. Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli.
Yang Y; Huang J; Mis MA; Estacion M; Macala L; Shah P; Schulman BR; Horton DB; Dib-Hajj SD; Waxman SG
J Neurosci; 2016 Jul; 36(28):7511-22. PubMed ID: 27413160
[TBL] [Abstract][Full Text] [Related]
6. Novel mutations mapping to the fourth sodium channel domain of Nav1.7 result in variable clinical manifestations of primary erythromelalgia.
Cregg R; Laguda B; Werdehausen R; Cox JJ; Linley JE; Ramirez JD; Bodi I; Markiewicz M; Howell KJ; Chen YC; Agnew K; Houlden H; Lunn MP; Bennett DL; Wood JN; Kinali M
Neuromolecular Med; 2013 Jun; 15(2):265-78. PubMed ID: 23292638
[TBL] [Abstract][Full Text] [Related]
7. Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation.
Wang L; Zellmer SG; Printzenhoff DM; Castle NA
Br J Pharmacol; 2015 Oct; 172(20):4905-18. PubMed ID: 26220736
[TBL] [Abstract][Full Text] [Related]
8. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity.
Sheets PL; Jackson JO; Waxman SG; Dib-Hajj SD; Cummins TR
J Physiol; 2007 Jun; 581(Pt 3):1019-31. PubMed ID: 17430993
[TBL] [Abstract][Full Text] [Related]
9. Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.
Eberhardt M; Nakajima J; Klinger AB; Neacsu C; Hühne K; O'Reilly AO; Kist AM; Lampe AK; Fischer K; Gibson J; Nau C; Winterpacht A; Lampert A
J Biol Chem; 2014 Jan; 289(4):1971-80. PubMed ID: 24311784
[TBL] [Abstract][Full Text] [Related]
10. Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity.
Kerth CM; Hautvast P; Körner J; Lampert A; Meents JE
J Biol Chem; 2021; 296():100227. PubMed ID: 33361158
[TBL] [Abstract][Full Text] [Related]
11. Dynamic-clamp analysis of wild-type human Nav1.7 and erythromelalgia mutant channel L858H.
Vasylyev DV; Han C; Zhao P; Dib-Hajj S; Waxman SG
J Neurophysiol; 2014 Apr; 111(7):1429-43. PubMed ID: 24401712
[TBL] [Abstract][Full Text] [Related]
12. Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
Wang GK; Russell C; Wang SY
J Physiol; 2004 Feb; 554(Pt 3):621-33. PubMed ID: 14608007
[TBL] [Abstract][Full Text] [Related]
13. A distinct molecular mechanism by which phenytoin rescues a novel long QT 3 variant.
Gando I; Campana C; Tan RB; Cecchin F; Sobie EA; Coetzee WA
J Mol Cell Cardiol; 2020 Jul; 144():1-11. PubMed ID: 32339567
[TBL] [Abstract][Full Text] [Related]
14. Preferred mexiletine block of human sodium channels with IVS4 mutations and its pH-dependence.
Mohammadi B; Jurkat-Rott K; Alekov A; Dengler R; Bufler J; Lehmann-Horn F
Pharmacogenet Genomics; 2005 Apr; 15(4):235-44. PubMed ID: 15864116
[TBL] [Abstract][Full Text] [Related]
15. A Novel SCN9A Mutation (F826Y) in Primary Erythromelalgia Alters the Excitability of Nav1.7.
Wu B; Zhang Y; Tang H; Yang M; Long H; Shi G; Tang J; Shi X
Curr Mol Med; 2017; 17(6):450-457. PubMed ID: 28990532
[TBL] [Abstract][Full Text] [Related]
16. Mexiletine-responsive erythromelalgia due to a new Na(v)1.7 mutation showing use-dependent current fall-off.
Choi JS; Zhang L; Dib-Hajj SD; Han C; Tyrrell L; Lin Z; Wang X; Yang Y; Waxman SG
Exp Neurol; 2009 Apr; 216(2):383-9. PubMed ID: 19162012
[TBL] [Abstract][Full Text] [Related]
17. Uncoupling sodium channel dimers restores the phenotype of a pain-linked Na
Rühlmann AH; Körner J; Hausmann R; Bebrivenski N; Neuhof C; Detro-Dassen S; Hautvast P; Benasolo CA; Meents J; Machtens JP; Schmalzing G; Lampert A
Br J Pharmacol; 2020 Oct; 177(19):4481-4496. PubMed ID: 32663327
[TBL] [Abstract][Full Text] [Related]
18. Gating of myotonic Na channel mutants defines the response to mexiletine and a potent derivative.
Desaphy JF; De Luca A; Tortorella P; De Vito D; George AL; Conte Camerino D
Neurology; 2001 Nov; 57(10):1849-57. PubMed ID: 11723275
[TBL] [Abstract][Full Text] [Related]
19. Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access.
Sasaki K; Makita N; Sunami A; Sakurada H; Shirai N; Yokoi H; Kimura A; Tohse N; Hiraoka M; Kitabatake A
Mol Pharmacol; 2004 Aug; 66(2):330-6. PubMed ID: 15266024
[TBL] [Abstract][Full Text] [Related]
20. Comparison of the effects of four Na+ channel analgesics on TTX-resistant Na+ currents in rat sensory neurons and recombinant Nav1.2 channels.
Weiser T
Neurosci Lett; 2006 Mar; 395(3):179-84. PubMed ID: 16293367
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
