219 related articles for article (PubMed ID: 24870023)
1. Kinetic characterization of human butyrylcholinesterase mutants for the hydrolysis of cocaethylene.
Hou S; Zhan M; Zheng X; Zhan CG; Zheng F
Biochem J; 2014 Jun; 460(3):447-57. PubMed ID: 24870023
[TBL] [Abstract][Full Text] [Related]
2. Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene.
Zheng X; Chen X; Zhang T; Zhan M; Zhan CG; Zheng F
Org Biomol Chem; 2020 Mar; 18(10):1968-1977. PubMed ID: 32101217
[TBL] [Abstract][Full Text] [Related]
3. Kinetic characterization of high-activity mutants of human butyrylcholinesterase for the cocaine metabolite norcocaine.
Zhan M; Hou S; Zhan CG; Zheng F
Biochem J; 2014 Jan; 457(1):197-206. PubMed ID: 24125115
[TBL] [Abstract][Full Text] [Related]
4. Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine.
Xue L; Hou S; Yang W; Fang L; Zheng F; Zhan CG
Chem Biol Interact; 2013 Mar; 203(1):57-62. PubMed ID: 22917637
[TBL] [Abstract][Full Text] [Related]
5. Kinetic characterization of cholinesterases and a therapeutically valuable cocaine hydrolase for their catalytic activities against heroin and its metabolite 6-monoacetylmorphine.
Kim K; Yao J; Jin Z; Zheng F; Zhan CG
Chem Biol Interact; 2018 Sep; 293():107-114. PubMed ID: 30080993
[TBL] [Abstract][Full Text] [Related]
6. Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine.
Xue L; Hou S; Tong M; Fang L; Chen X; Jin Z; Tai HH; Zheng F; Zhan CG
Biochem J; 2013 Aug; 453(3):447-54. PubMed ID: 23849058
[TBL] [Abstract][Full Text] [Related]
7. An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient.
Xie W; Altamirano CV; Bartels CF; Speirs RJ; Cashman JR; Lockridge O
Mol Pharmacol; 1999 Jan; 55(1):83-91. PubMed ID: 9882701
[TBL] [Abstract][Full Text] [Related]
8. Substrate selectivity of high-activity mutants of human butyrylcholinesterase.
Hou S; Xue L; Yang W; Fang L; Zheng F; Zhan CG
Org Biomol Chem; 2013 Nov; 11(43):7477-85. PubMed ID: 24077614
[TBL] [Abstract][Full Text] [Related]
9. Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine.
Yang W; Xue L; Fang L; Chen X; Zhan CG
Chem Biol Interact; 2010 Sep; 187(1-3):148-52. PubMed ID: 20060817
[TBL] [Abstract][Full Text] [Related]
10. Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants.
Hamza A; Cho H; Tai HH; Zhan CG
J Phys Chem B; 2005 Mar; 109(10):4776-82. PubMed ID: 16851561
[TBL] [Abstract][Full Text] [Related]
11. Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine.
Xue L; Ko MC; Tong M; Yang W; Hou S; Fang L; Liu J; Zheng F; Woods JH; Tai HH; Zhan CG
Mol Pharmacol; 2011 Feb; 79(2):290-7. PubMed ID: 20971807
[TBL] [Abstract][Full Text] [Related]
12. Computational redesign of human butyrylcholinesterase for anticocaine medication.
Pan Y; Gao D; Yang W; Cho H; Yang G; Tai HH; Zhan CG
Proc Natl Acad Sci U S A; 2005 Nov; 102(46):16656-61. PubMed ID: 16275916
[TBL] [Abstract][Full Text] [Related]
13. Design of high-activity mutants of human butyrylcholinesterase against (-)-cocaine: structural and energetic factors affecting the catalytic efficiency.
Zheng F; Yang W; Xue L; Hou S; Liu J; Zhan CG
Biochemistry; 2010 Oct; 49(42):9113-9. PubMed ID: 20886866
[TBL] [Abstract][Full Text] [Related]
14. Re-engineering butyrylcholinesterase as a cocaine hydrolase.
Sun H; Pang YP; Lockridge O; Brimijoin S
Mol Pharmacol; 2002 Aug; 62(2):220-4. PubMed ID: 12130672
[TBL] [Abstract][Full Text] [Related]
15. Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase.
Fang L; Hou S; Xue L; Zheng F; Zhan CG
Chem Biol Interact; 2014 May; 214():18-25. PubMed ID: 24582612
[TBL] [Abstract][Full Text] [Related]
16. Rational design of an enzyme mutant for anti-cocaine therapeutics.
Zheng F; Zhan CG
J Comput Aided Mol Des; 2008 Sep; 22(9):661-71. PubMed ID: 17989928
[TBL] [Abstract][Full Text] [Related]
17. TV-1380 attenuates cocaine-induced changes in cardiodynamic parameters in monkeys and reduces the formation of cocaethylene.
Shemesh-Darvish L; Shinar D; Hallak H; Gross A; Rosenstock M
Drug Alcohol Depend; 2018 Jul; 188():295-303. PubMed ID: 29807217
[TBL] [Abstract][Full Text] [Related]
18. Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication.
Sun H; El Yazal J; Lockridge O; Schopfer LM; Brimijoin S; Pang YP
J Biol Chem; 2001 Mar; 276(12):9330-6. PubMed ID: 11104759
[TBL] [Abstract][Full Text] [Related]
19. Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase.
Yang W; Pan Y; Zheng F; Cho H; Tai HH; Zhan CG
Biophys J; 2009 Mar; 96(5):1931-8. PubMed ID: 19254552
[TBL] [Abstract][Full Text] [Related]
20. Effects of a cocaine hydrolase engineered from human butyrylcholinesterase on metabolic profile of cocaine in rats.
Chen X; Zheng X; Zhou Z; Zhan CG; Zheng F
Chem Biol Interact; 2016 Nov; 259(Pt B):104-109. PubMed ID: 27154495
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
