These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 24870023)

  • 21. Human Butyrylcholinesterase Mutants for (-)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole.
    Zheng F; Hou S; Xue L; Yang W; Zhan CG
    J Phys Chem B; 2023 Dec; 127(50):10723-10729. PubMed ID: 38063500
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Free energy perturbation simulation on transition states and high-activity mutants of human butyrylcholinesterase for (-)-cocaine hydrolysis.
    Yang W; Pan Y; Fang L; Gao D; Zheng F; Zhan CG
    J Phys Chem B; 2010 Aug; 114(33):10889-96. PubMed ID: 20677742
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine.
    Zhan M; Hou S; Shang L; Chen X; Zhan CG; Zheng F
    Org Biomol Chem; 2023 May; 21(17):3650-3659. PubMed ID: 37067022
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity.
    Larrimore KE; Barcus M; Kannan L; Gao Y; Zhan CG; Brimijoin S; Mor T
    Chem Biol Interact; 2013 Mar; 203(1):217-20. PubMed ID: 23000451
    [TBL] [Abstract][Full Text] [Related]  

  • 25. DNA sequence of butyrylcholinesterase from the rat: expression of the protein and characterization of the properties of rat butyrylcholinesterase.
    Boeck AT; Schopfer LM; Lockridge O
    Biochem Pharmacol; 2002 Jun; 63(12):2101-10. PubMed ID: 12110369
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine.
    Shang L; Jin Z; Wei H; Park S; Zhan CG; Zheng F
    Sci Rep; 2023 Jan; 13(1):640. PubMed ID: 36635293
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity.
    Duysen EG; Bartels CF; Lockridge O
    J Pharmacol Exp Ther; 2002 Aug; 302(2):751-8. PubMed ID: 12130740
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Fundamental reaction mechanism for cocaine hydrolysis in human butyrylcholinesterase.
    Zhan CG; Zheng F; Landry DW
    J Am Chem Soc; 2003 Mar; 125(9):2462-74. PubMed ID: 12603134
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cocaine and alcohol interactions in the rat: contribution of cocaine metabolites to the pharmacological effects.
    Pan WJ; Hedaya MA
    J Pharm Sci; 1999 Apr; 88(4):468-76. PubMed ID: 10187759
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Cocaethylene metabolism and interaction with cocaine and ethanol: role of carboxylesterases.
    Laizure SC; Mandrell T; Gades NM; Parker RB
    Drug Metab Dispos; 2003 Jan; 31(1):16-20. PubMed ID: 12485948
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase.
    Chen X; Huang X; Geng L; Xue L; Hou S; Zheng X; Brimijoin S; Zheng F; Zhan CG
    Biochem J; 2015 Mar; 466(2):243-51. PubMed ID: 25486543
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metabolic Enzymes of Cocaine Metabolite Benzoylecgonine.
    Chen X; Zheng X; Zhan M; Zhou Z; Zhan CG; Zheng F
    ACS Chem Biol; 2016 Aug; 11(8):2186-94. PubMed ID: 27224254
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase.
    Sun H; Shen ML; Pang YP; Lockridge O; Brimijoin S
    J Pharmacol Exp Ther; 2002 Aug; 302(2):710-6. PubMed ID: 12130735
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Free energy perturbation (FEP) simulation on the transition states of cocaine hydrolysis catalyzed by human butyrylcholinesterase and its mutants.
    Pan Y; Gao D; Yang W; Cho H; Zhan CG
    J Am Chem Soc; 2007 Nov; 129(44):13537-43. PubMed ID: 17927177
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Prolonged toxic effects after cocaine challenge in butyrylcholinesterase/plasma carboxylesterase double knockout mice: a model for butyrylcholinesterase-deficient humans.
    Duysen EG; Lockridge O
    Drug Metab Dispos; 2011 Aug; 39(8):1321-3. PubMed ID: 21540357
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Visualizing viral transduction of a cocaine-hydrolyzing, human butyrylcholinesterase in rats.
    Gao Y; Brimijoin S
    Chem Biol Interact; 2005 Dec; 157-158():97-103. PubMed ID: 16243302
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Most efficient cocaine hydrolase designed by virtual screening of transition states.
    Zheng F; Yang W; Ko MC; Liu J; Cho H; Gao D; Tong M; Tai HH; Woods JH; Zhan CG
    J Am Chem Soc; 2008 Sep; 130(36):12148-55. PubMed ID: 18710224
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A highly efficient cocaine-detoxifying enzyme obtained by computational design.
    Zheng F; Xue L; Hou S; Liu J; Zhan M; Yang W; Zhan CG
    Nat Commun; 2014 Mar; 5():3457. PubMed ID: 24643289
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Modeling evolution of hydrogen bonding and stabilization of transition states in the process of cocaine hydrolysis catalyzed by human butyrylcholinesterase.
    Gao D; Zhan CG
    Proteins; 2006 Jan; 62(1):99-110. PubMed ID: 16288482
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction.
    Zheng F; Zhan CG
    Org Biomol Chem; 2008 Mar; 6(5):836-43. PubMed ID: 18292872
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.