BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

299 related articles for article (PubMed ID: 24871945)

  • 1. APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction.
    Wan L; Tan M; Yang J; Inuzuka H; Dai X; Wu T; Liu J; Shaik S; Chen G; Deng J; Malumbres M; Letai A; Kirschner MW; Sun Y; Wei W
    Dev Cell; 2014 May; 29(4):377-91. PubMed ID: 24871945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tax contributes apoptosis resistance to HTLV-1-infected T cells via suppression of Bid and Bim expression.
    Mühleisen A; Giaisi M; Köhler R; Krammer PH; Li-Weber M
    Cell Death Dis; 2014 Dec; 5(12):e1575. PubMed ID: 25522269
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax.
    Higuchi M; Takahashi M; Tanaka Y; Fujii M
    Cancer Med; 2014 Dec; 3(6):1605-14. PubMed ID: 25175936
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.
    Jia L; Li B; Yu H
    Nat Commun; 2016 Feb; 7():10818. PubMed ID: 26912231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest.
    May KM; Paldi F; Hardwick KG
    Curr Biol; 2017 Apr; 27(8):1221-1228. PubMed ID: 28366744
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of ubiquitylation of components of mitotic checkpoint complex in their dissociation from anaphase-promoting complex/cyclosome.
    Sitry-Shevah D; Kaisari S; Teichner A; Miniowitz-Shemtov S; Hershko A
    Proc Natl Acad Sci U S A; 2018 Feb; 115(8):1777-1782. PubMed ID: 29432156
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31(comet).
    Jia L; Li B; Warrington RT; Hao X; Wang S; Yu H
    Mol Biol Cell; 2011 Nov; 22(22):4227-35. PubMed ID: 21937719
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule.
    Liu B; Hong S; Tang Z; Yu H; Giam CZ
    Proc Natl Acad Sci U S A; 2005 Jan; 102(1):63-8. PubMed ID: 15623561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Up-regulation of pro-apoptotic protein Bim and down-regulation of anti-apoptotic protein Mcl-1 cooperatively mediate enhanced tumor cell death induced by the combination of ERK kinase (MEK) inhibitor and microtubule inhibitor.
    Kawabata T; Tanimura S; Asai K; Kawasaki R; Matsumaru Y; Kohno M
    J Biol Chem; 2012 Mar; 287(13):10289-10300. PubMed ID: 22270368
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint.
    Foss KM; Robeson AC; Kornbluth S; Zhang L
    Cell Cycle; 2016; 15(2):225-33. PubMed ID: 26652909
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BimEL is phosphorylated at mitosis by Aurora A and targeted for degradation by βTrCP1.
    Moustafa-Kamal M; Gamache I; Lu Y; Li S; Teodoro JG
    Cell Death Differ; 2013 Oct; 20(10):1393-403. PubMed ID: 23912711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hematopoietic PBX-interacting protein is a substrate and an inhibitor of the APC/C-Cdc20 complex and regulates mitosis by stabilizing cyclin B1.
    Khumukcham SS; Samanthapudi VSK; Penugurti V; Kumari A; Kesavan PS; Velatooru LR; Kotla SR; Mazumder A; Manavathi B
    J Biol Chem; 2019 Jun; 294(26):10236-10252. PubMed ID: 31101654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nek2A destruction marks APC/C activation at the prophase-to-prometaphase transition by spindle-checkpoint-restricted Cdc20.
    Boekhout M; Wolthuis R
    J Cell Sci; 2015 Apr; 128(8):1639-53. PubMed ID: 25673878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cdc20 proteolysis requires p38 MAPK signaling and Cdh1-independent APC/C ubiquitination during spindle assembly checkpoint activation by cadmium.
    Yen AH; Yang JL
    J Cell Physiol; 2010 May; 223(2):327-34. PubMed ID: 20054826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An E2 enzyme Ubc11 is required for ubiquitination of Slp1/Cdc20 and spindle checkpoint silencing in fission yeast.
    Horikoshi Y; Habu T; Matsumoto T
    Cell Cycle; 2013 Mar; 12(6):961-71. PubMed ID: 23442800
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NUP98 fusion oncoproteins interact with the APC/C(Cdc20) as a pseudosubstrate and prevent mitotic checkpoint complex binding.
    Salsi V; Fantini S; Zappavigna V
    Cell Cycle; 2016 Sep; 15(17):2275-87. PubMed ID: 27097363
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR; Jun do Y; Lee JY; Kim YH
    Apoptosis; 2014 Jan; 19(1):224-40. PubMed ID: 24166139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint.
    Hein JB; Nilsson J
    EMBO Rep; 2014 Mar; 15(3):264-72. PubMed ID: 24464857
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of Bim in apoptosis induced in H460 lung tumor cells by the spindle poison Combretastatin-A4.
    Mendez G; Policarpi C; Cenciarelli C; Tanzarella C; Antoccia A
    Apoptosis; 2011 Sep; 16(9):940-9. PubMed ID: 21671007
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.
    Foster SA; Morgan DO
    Mol Cell; 2012 Sep; 47(6):921-32. PubMed ID: 22940250
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.