BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 24877142)

  • 1. Accumulation of misfolded SOD1 in dorsal root ganglion degenerating proprioceptive sensory neurons of transgenic mice with amyotrophic lateral sclerosis.
    Sábado J; Casanovas A; Tarabal O; Hereu M; Piedrafita L; Calderó J; Esquerda JE
    Biomed Res Int; 2014; 2014():852163. PubMed ID: 24877142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutant SOD1 accumulation in sensory neurons does not associate with endoplasmic reticulum stress features: Implications for differential vulnerability of sensory and motor neurons to SOD1 toxicity.
    Taiana M; Sassone J; Lauria G
    Neurosci Lett; 2016 Aug; 627():107-14. PubMed ID: 27241719
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic amyotrophic lateral sclerosis (ALS) model mice.
    Zetterström P; Graffmo KS; Andersen PM; Brännström T; Marklund SL
    J Biol Chem; 2011 Jun; 286(23):20130-6. PubMed ID: 21493711
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sensory involvement in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.
    Guo YS; Wu DX; Wu HR; Wu SY; Yang C; Li B; Bu H; Zhang YS; Li CY
    Exp Mol Med; 2009 Mar; 41(3):140-50. PubMed ID: 19293633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of thoracic motor and sensory neurons and spinal nerve roots in canine degenerative myelopathy, a potential disease model of amyotrophic lateral sclerosis.
    Morgan BR; Coates JR; Johnson GC; Shelton GD; Katz ML
    J Neurosci Res; 2014 Apr; 92(4):531-41. PubMed ID: 24375814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin.
    Sassone J; Taiana M; Lombardi R; Porretta-Serapiglia C; Freschi M; Bonanno S; Marcuzzo S; Caravello F; Bendotti C; Lauria G
    Hum Mol Genet; 2016 Apr; 25(8):1588-99. PubMed ID: 26908600
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting of monomer/misfolded SOD1 as a therapeutic strategy for amyotrophic lateral sclerosis.
    Liu HN; Tjostheim S; Dasilva K; Taylor D; Zhao B; Rakhit R; Brown M; Chakrabartty A; McLaurin J; Robertson J
    J Neurosci; 2012 Jun; 32(26):8791-9. PubMed ID: 22745481
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Milanese M; Giribaldi F; Melone M; Bonifacino T; Musante I; Carminati E; Rossi PI; Vergani L; Voci A; Conti F; Puliti A; Bonanno G
    Neurobiol Dis; 2014 Apr; 64():48-59. PubMed ID: 24361555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1
    Salvany S; Casanovas A; Piedrafita L; Gras S; Calderó J; Esquerda JE
    Brain Pathol; 2022 Nov; 32(6):e13078. PubMed ID: 35584812
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
    Crippa V; Sau D; Rusmini P; Boncoraglio A; Onesto E; Bolzoni E; Galbiati M; Fontana E; Marino M; Carra S; Bendotti C; De Biasi S; Poletti A
    Hum Mol Genet; 2010 Sep; 19(17):3440-56. PubMed ID: 20570967
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice.
    Pan L; Yoshii Y; Otomo A; Ogawa H; Iwasaki Y; Shang HF; Hadano S
    PLoS One; 2012; 7(3):e33409. PubMed ID: 22438926
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways.
    Ayers JI; Fromholt SE; O'Neal VM; Diamond JH; Borchelt DR
    Acta Neuropathol; 2016 Jan; 131(1):103-14. PubMed ID: 26650262
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.
    Thomsen GM; Gowing G; Latter J; Chen M; Vit JP; Staggenborg K; Avalos P; Alkaslasi M; Ferraiuolo L; Likhite S; Kaspar BK; Svendsen CN
    J Neurosci; 2014 Nov; 34(47):15587-600. PubMed ID: 25411487
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.
    Pokrishevsky E; Grad LI; Yousefi M; Wang J; Mackenzie IR; Cashman NR
    PLoS One; 2012; 7(4):e35050. PubMed ID: 22493728
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.
    Rakhit R; Robertson J; Vande Velde C; Horne P; Ruth DM; Griffin J; Cleveland DW; Cashman NR; Chakrabartty A
    Nat Med; 2007 Jun; 13(6):754-9. PubMed ID: 17486090
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.
    Urushitani M; Kurisu J; Tsukita K; Takahashi R
    J Neurochem; 2002 Dec; 83(5):1030-42. PubMed ID: 12437574
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.
    Martin LJ
    Rev Neurosci; 2007; 18(2):115-36. PubMed ID: 17593875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxidized/misfolded superoxide dismutase-1: the cause of all amyotrophic lateral sclerosis?
    Kabashi E; Valdmanis PN; Dion P; Rouleau GA
    Ann Neurol; 2007 Dec; 62(6):553-9. PubMed ID: 18074357
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.
    Li QX; Mok SS; Laughton KM; McLean CA; Volitakis I; Cherny RA; Cheung NS; White AR; Masters CL
    Aging Cell; 2006 Apr; 5(2):153-65. PubMed ID: 16626394
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.