BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 24877563)

  • 1. PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
    Sajan MP; Ivey RA; Lee M; Mastorides S; Jurczak MJ; Samuels VT; Shulman GI; Braun U; Leitges M; Farese RV
    Mol Endocrinol; 2014 Jul; 28(7):1097-107. PubMed ID: 24877563
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ι.
    Sajan MP; Nimal S; Mastorides S; Acevedo-Duncan M; Kahn CR; Fields AP; Braun U; Leitges M; Farese RV
    Metabolism; 2012 Apr; 61(4):459-69. PubMed ID: 22225955
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin signalling in hepatocytes of humans with type 2 diabetes: excessive production and activity of protein kinase C-ι (PKC-ι) and dependent processes and reversal by PKC-ι inhibitors.
    Sajan MP; Farese RV
    Diabetologia; 2012 May; 55(5):1446-57. PubMed ID: 22349071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ
    Sajan MP; Hansen BC; Higgs MG; Kahn CR; Braun U; Leitges M; Park CR; Diamond DM; Farese RV
    Neurobiol Aging; 2018 Jan; 61():225-237. PubMed ID: 29032894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance.
    Stöhr O; Tao R; Miao J; Copps KD; White MF
    Cell Rep; 2021 Mar; 34(12):108893. PubMed ID: 33761350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pancreastatin-dependent inflammatory signaling mediates obesity-induced insulin resistance.
    Bandyopadhyay GK; Lu M; Avolio E; Siddiqui JA; Gayen JR; Wollam J; Vu CU; Chi NW; O'Connor DT; Mahata SK
    Diabetes; 2015 Jan; 64(1):104-16. PubMed ID: 25048197
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity.
    Penniman CM; Suarez Beltran PA; Bhardwaj G; Junck TL; Jena J; Poro K; Hirshman MF; Goodyear LJ; O'Neill BT
    Mol Metab; 2019 Dec; 30():203-220. PubMed ID: 31767172
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase.
    Zhou B; Zhang Y; Li S; Wu L; Fejes-Toth G; Naray-Fejes-Toth A; Soukas AA
    Cell Rep; 2021 Oct; 37(1):109785. PubMed ID: 34610303
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors.
    Sutton GM; Trevaskis JL; Hulver MW; McMillan RP; Markward NJ; Babin MJ; Meyer EA; Butler AA
    Endocrinology; 2006 May; 147(5):2183-96. PubMed ID: 16469808
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.
    Knauf C; Cani PD; Perrin C; Iglesias MA; Maury JF; Bernard E; Benhamed F; Grémeaux T; Drucker DJ; Kahn CR; Girard J; Tanti JF; Delzenne NM; Postic C; Burcelin R
    J Clin Invest; 2005 Dec; 115(12):3554-63. PubMed ID: 16322793
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.
    Aryal B; Singh AK; Zhang X; Varela L; Rotllan N; Goedeke L; Chaube B; Camporez JP; Vatner DF; Horvath TL; Shulman GI; Suárez Y; Fernández-Hernando C
    JCI Insight; 2018 Mar; 3(6):. PubMed ID: 29563332
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway.
    Yao S; Zhang J; Zhan Y; Shi Y; Yu Y; Zheng L; Xu N; Luo G
    Endocr Metab Immune Disord Drug Targets; 2020; 20(5):771-780. PubMed ID: 31702495
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue.
    Homan EP; Brandão BB; Softic S; El Ouaamari A; O'Neill BT; Kulkarni RN; Kim JK; Kahn CR
    J Clin Invest; 2021 Oct; 131(19):. PubMed ID: 34428182
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.
    Pajvani UB; Shawber CJ; Samuel VT; Birkenfeld AL; Shulman GI; Kitajewski J; Accili D
    Nat Med; 2011 Jul; 17(8):961-7. PubMed ID: 21804540
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel pathway of insulin sensitivity in chromogranin A null mice: a crucial role for pancreastatin in glucose homeostasis.
    Gayen JR; Saberi M; Schenk S; Biswas N; Vaingankar SM; Cheung WW; Najjar SM; O'Connor DT; Bandyopadhyay G; Mahata SK
    J Biol Chem; 2009 Oct; 284(42):28498-509. PubMed ID: 19706599
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Higher protein kinase C ζ in fatty rat liver and its effect on insulin actions in primary hepatocytes.
    Chen W; Goff MR; Kuang H; Chen G
    PLoS One; 2015; 10(3):e0121890. PubMed ID: 25822413
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice.
    Kim T; Nason S; Antipenko J; Finan B; Shalev A; DiMarchi R; Habegger KM
    Diabetes; 2022 Oct; 71(10):2123-2135. PubMed ID: 35877180
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein kinase C iota facilitates insulin-induced glucose transport by phosphorylation of soluble nSF attachment protein receptor regulator (SNARE) double C2 domain protein b.
    Nomiyama R; Emoto M; Fukuda N; Matsui K; Kondo M; Sakane A; Sasaki T; Tanizawa Y
    J Diabetes Investig; 2019 May; 10(3):591-601. PubMed ID: 30369065
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta.
    Garofalo RS; Orena SJ; Rafidi K; Torchia AJ; Stock JL; Hildebrandt AL; Coskran T; Black SC; Brees DJ; Wicks JR; McNeish JD; Coleman KG
    J Clin Invest; 2003 Jul; 112(2):197-208. PubMed ID: 12843127
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus.
    Sajan MP; Hansen BC; Acevedo-Duncan M; Kindy MS; Cooper DR; Farese RV
    MedComm (2020); 2021 Mar; 2(1):3-16. PubMed ID: 34766133
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.