201 related articles for article (PubMed ID: 24881566)
1. Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Sparks SM; Chen G; Collins JL; Danger D; Dock ST; Jayawickreme C; Jenkinson S; Laudeman C; Leesnitzer MA; Liang X; Maloney P; McCoy DC; Moncol D; Rash V; Rimele T; Vulimiri P; Way JM; Ross S
Bioorg Med Chem Lett; 2014 Jul; 24(14):3100-3. PubMed ID: 24881566
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists.
Xu F; Zhao Y; Zhou H; Li C; Zhang X; Hou T; Qu L; Wei L; Wang J; Liu Y; Liang X
Bioorg Med Chem Lett; 2020 Dec; 30(24):127650. PubMed ID: 33127539
[TBL] [Abstract][Full Text] [Related]
3. Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist.
Sparks SM; Aquino C; Banker P; Collins JL; Cowan D; Diaz C; Dock ST; Hertzog DL; Liang X; Swiger ED; Yuen J; Chen G; Jayawickreme C; Moncol D; Nystrom C; Rash V; Rimele T; Roller S; Ross S
Bioorg Med Chem Lett; 2017 Mar; 27(5):1278-1283. PubMed ID: 28148462
[TBL] [Abstract][Full Text] [Related]
4. Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity.
Azevedo CM; Watterson KR; Wargent ET; Hansen SV; Hudson BD; Kępczyńska MA; Dunlop J; Shimpukade B; Christiansen E; Milligan G; Stocker CJ; Ulven T
J Med Chem; 2016 Oct; 59(19):8868-8878. PubMed ID: 27570890
[TBL] [Abstract][Full Text] [Related]
5. Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases.
Christiansen E; Watterson KR; Stocker CJ; Sokol E; Jenkins L; Simon K; Grundmann M; Petersen RK; Wargent ET; Hudson BD; Kostenis E; Ejsing CS; Cawthorne MA; Milligan G; Ulven T
Br J Nutr; 2015 Jun; 113(11):1677-88. PubMed ID: 25916176
[TBL] [Abstract][Full Text] [Related]
6. Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4.
Watterson KR; Hansen SVF; Hudson BD; Alvarez-Curto E; Raihan SZ; Azevedo CMG; Martin G; Dunlop J; Yarwood SJ; Ulven T; Milligan G
Mol Pharmacol; 2017 Jun; 91(6):630-641. PubMed ID: 28385906
[TBL] [Abstract][Full Text] [Related]
7. The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism.
Hudson BD; Shimpukade B; Mackenzie AE; Butcher AJ; Pediani JD; Christiansen E; Heathcote H; Tobin AB; Ulven T; Milligan G
Mol Pharmacol; 2013 Nov; 84(5):710-25. PubMed ID: 23979972
[TBL] [Abstract][Full Text] [Related]
8. Receptor tyrosine kinase activation induces free fatty acid 4 receptor phosphorylation, β-arrestin interaction, and internalization.
Villegas-Comonfort S; Guzmán-Silva A; Romero-Ávila MT; Takei Y; Tsujimoto G; Hirasawa A; García-Sáinz JA
Eur J Pharmacol; 2019 Jul; 855():267-275. PubMed ID: 31078517
[TBL] [Abstract][Full Text] [Related]
9. Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases.
Wannick M; Bezdek S; Guillen N; Thieme M; Meshrkey F; Mousavi S; Seeling M; Nimmerjahn F; Mócsai A; Zillikens D; Sezin T; Sadik CD
Pharmacol Res Perspect; 2018 Dec; 6(6):e00438. PubMed ID: 30455959
[TBL] [Abstract][Full Text] [Related]
10. Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics.
Li A; Yang D; Zhu M; Tsai KC; Xiao KH; Yu X; Sun J; Du L
Future Med Chem; 2015; 7(18):2429-37. PubMed ID: 26653412
[TBL] [Abstract][Full Text] [Related]
11. Targeting FFA1 and FFA4 receptors in cancer-induced cachexia.
Freitas RDS; Muradás TC; Dagnino APA; Rost FL; Costa KM; Venturin GT; Greggio S; da Costa JC; Campos MM
Am J Physiol Endocrinol Metab; 2020 Nov; 319(5):E877-E892. PubMed ID: 32893672
[TBL] [Abstract][Full Text] [Related]
12. Omega-3 fatty acids and other FFA4 agonists inhibit growth factor signaling in human prostate cancer cells.
Liu Z; Hopkins MM; Zhang Z; Quisenberry CB; Fix LC; Galvan BM; Meier KE
J Pharmacol Exp Ther; 2015 Feb; 352(2):380-94. PubMed ID: 25491146
[TBL] [Abstract][Full Text] [Related]
13. Improving metabolic stability with deuterium: The discovery of GPU-028, a potent free fatty acid receptor 4 agonists.
Li Z; Xu X; Li G; Fu X; Liu Y; Feng Y; Wang M; Ouyang Y; Han J
Bioorg Med Chem; 2017 Dec; 25(24):6647-6652. PubMed ID: 29100735
[TBL] [Abstract][Full Text] [Related]
14. The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120).
Hudson BD; Shimpukade B; Milligan G; Ulven T
J Biol Chem; 2014 Jul; 289(29):20345-58. PubMed ID: 24860101
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120).
Hansen SV; Ulven T
Handb Exp Pharmacol; 2017; 236():33-56. PubMed ID: 27807695
[TBL] [Abstract][Full Text] [Related]
16. FFA4 receptor (GPR120): A hot target for the development of anti-diabetic therapies.
Liu HD; Wang WB; Xu ZG; Liu CH; He DF; Du LP; Li MY; Yu X; Sun JP
Eur J Pharmacol; 2015 Sep; 763(Pt B):160-8. PubMed ID: 26123847
[TBL] [Abstract][Full Text] [Related]
17. Identification and target-pathway deconvolution of FFA4 agonists with anti-diabetic activity from Arnebia euchroma (Royle) Johnst.
Xu F; Wang P; Zhang X; Hou T; Qu L; Wang C; Wang J; Liu Y; Liang X
Pharmacol Res; 2021 Jan; 163():105173. PubMed ID: 33027715
[TBL] [Abstract][Full Text] [Related]
18. Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.
Milligan G; Alvarez-Curto E; Watterson KR; Ulven T; Hudson BD
Br J Pharmacol; 2015 Jul; 172(13):3254-65. PubMed ID: 25131623
[TBL] [Abstract][Full Text] [Related]
19. FFA4/GPR120: Pharmacology and Therapeutic Opportunities.
Milligan G; Alvarez-Curto E; Hudson BD; Prihandoko R; Tobin AB
Trends Pharmacol Sci; 2017 Sep; 38(9):809-821. PubMed ID: 28734639
[TBL] [Abstract][Full Text] [Related]
20. Development of Free Fatty Acid Receptor 4 (FFA4/GPR120) Agonists in Health Science.
Son SE; Kim NJ; Im DS
Biomol Ther (Seoul); 2021 Jan; 29(1):22-30. PubMed ID: 33372166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
