These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 24883232)

  • 1. Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma.
    Tucker BA; Solivan-Timpe F; Roos BR; Anfinson KR; Robin AL; Wiley LA; Mullins RF; Fingert JH
    J Stem Cell Res Ther; 2014 Jan; 3(5):161. PubMed ID: 24883232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transgenic TBK1 mice have features of normal tension glaucoma.
    Fingert JH; Miller K; Hedberg-Buenz A; Roos BR; Lewis CJ; Mullins RF; Anderson MG
    Hum Mol Genet; 2017 Jan; 26(1):124-132. PubMed ID: 28025332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptome analysis of the zebrafish
    Covello G; Rossello FJ; Filosi M; Gajardo F; Duchemin AL; Tremonti BF; Eichenlaub M; Polo JM; Powell D; Ngai J; Allende ML; Domenici E; Ramialison M; Poggi L
    FASEB Bioadv; 2020 Jul; 2(7):434-448. PubMed ID: 32676583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration.
    Ohlemacher SK; Sridhar A; Xiao Y; Hochstetler AE; Sarfarazi M; Cummins TR; Meyer JS
    Stem Cells; 2016 Jun; 34(6):1553-62. PubMed ID: 26996528
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease.
    Pottier C; Bieniek KF; Finch N; van de Vorst M; Baker M; Perkersen R; Brown P; Ravenscroft T; van Blitterswijk M; Nicholson AM; DeTure M; Knopman DS; Josephs KA; Parisi JE; Petersen RC; Boylan KB; Boeve BF; Graff-Radford NR; Veltman JA; Gilissen C; Murray ME; Dickson DW; Rademakers R
    Acta Neuropathol; 2015 Jul; 130(1):77-92. PubMed ID: 25943890
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Motor neuron disease: loss-of-function mutations in TBK1 can cause familial ALS.
    Chase A
    Nat Rev Neurol; 2015 May; 11(5):246. PubMed ID: 25848921
    [No Abstract]   [Full Text] [Related]  

  • 7. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.
    Cirulli ET; Lasseigne BN; Petrovski S; Sapp PC; Dion PA; Leblond CS; Couthouis J; Lu YF; Wang Q; Krueger BJ; Ren Z; Keebler J; Han Y; Levy SE; Boone BE; Wimbish JR; Waite LL; Jones AL; Carulli JP; Day-Williams AG; Staropoli JF; Xin WW; Chesi A; Raphael AR; McKenna-Yasek D; Cady J; Vianney de Jong JM; Kenna KP; Smith BN; Topp S; Miller J; Gkazi A; ; Al-Chalabi A; van den Berg LH; Veldink J; Silani V; Ticozzi N; Shaw CE; Baloh RH; Appel S; Simpson E; Lagier-Tourenne C; Pulst SM; Gibson S; Trojanowski JQ; Elman L; McCluskey L; Grossman M; Shneider NA; Chung WK; Ravits JM; Glass JD; Sims KB; Van Deerlin VM; Maniatis T; Hayes SD; Ordureau A; Swarup S; Landers J; Baas F; Allen AS; Bedlack RS; Harper JW; Gitler AD; Rouleau GA; Brown R; Harms MB; Cooper GM; Harris T; Myers RM; Goldstein DB
    Science; 2015 Mar; 347(6229):1436-41. PubMed ID: 25700176
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism.
    Shen WC; Li HY; Chen GC; Chern Y; Tu PH
    Autophagy; 2015 Apr; 11(4):685-700. PubMed ID: 25484089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa.
    Yoshida T; Ozawa Y; Suzuki K; Yuki K; Ohyama M; Akamatsu W; Matsuzaki Y; Shimmura S; Mitani K; Tsubota K; Okano H
    Mol Brain; 2014 Jun; 7():45. PubMed ID: 24935155
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia.
    Freischmidt A; Wieland T; Richter B; Ruf W; Schaeffer V; Müller K; Marroquin N; Nordin F; Hübers A; Weydt P; Pinto S; Press R; Millecamps S; Molko N; Bernard E; Desnuelle C; Soriani MH; Dorst J; Graf E; Nordström U; Feiler MS; Putz S; Boeckers TM; Meyer T; Winkler AS; Winkelman J; de Carvalho M; Thal DR; Otto M; Brännström T; Volk AE; Kursula P; Danzer KM; Lichtner P; Dikic I; Meitinger T; Ludolph AC; Strom TM; Andersen PM; Weishaupt JH
    Nat Neurosci; 2015 May; 18(5):631-6. PubMed ID: 25803835
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
    Li F; Xie X; Wang Y; Liu J; Cheng X; Guo Y; Gong Y; Hu S; Pan L
    Nat Commun; 2016 Sep; 7():12708. PubMed ID: 27620379
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SQSTM1 Mutations and Glaucoma.
    Scheetz TE; Roos BR; Solivan-Timpe F; Miller K; DeLuca AP; Stone EM; Kwon YH; Alward WL; Wang K; Fingert JH
    PLoS One; 2016; 11(6):e0156001. PubMed ID: 27275741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin.
    Sirohi K; Kumari A; Radha V; Swarup G
    PLoS One; 2015; 10(9):e0138289. PubMed ID: 26376340
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma.
    Liu Y; Garrett ME; Yaspan BL; Bailey JC; Loomis SJ; Brilliant M; Budenz DL; Christen WG; Fingert JH; Gaasterland D; Gaasterland T; Kang JH; Lee RK; Lichter P; Moroi SE; Realini A; Richards JE; Schuman JS; Scott WK; Singh K; Sit AJ; Vollrath D; Weinreb R; Wollstein G; Zack DJ; Zhang K; Pericak-Vance MA; Haines JL; Pasquale LR; Wiggs JL; Allingham RR; Ashley-Koch AE; Hauser MA
    Invest Ophthalmol Vis Sci; 2014 Nov; 55(12):8251-8. PubMed ID: 25414181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SUMO modification of TBK1 at the adaptor-binding C-terminal coiled-coil domain contributes to its antiviral activity.
    Saul VV; Niedenthal R; Pich A; Weber F; Schmitz ML
    Biochim Biophys Acta; 2015 Jan; 1853(1):136-43. PubMed ID: 25409927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional analysis of optineurin and some of its disease-associated mutants.
    Bansal M; Swarup G; Balasubramanian D
    IUBMB Life; 2015 Feb; 67(2):120-8. PubMed ID: 25855473
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Primary fibroblasts cultures reveal TDP-43 abnormalities in amyotrophic lateral sclerosis patients with and without SOD1 mutations.
    Sabatelli M; Zollino M; Conte A; Del Grande A; Marangi G; Lucchini M; Mirabella M; Romano A; Piacentini R; Bisogni G; Lattante S; Luigetti M; Rossini PM; Moncada A
    Neurobiol Aging; 2015 May; 36(5):2005.e5-2005.e13. PubMed ID: 25792239
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases.
    Wiley LA; Burnight ER; Songstad AE; Drack AV; Mullins RF; Stone EM; Tucker BA
    Prog Retin Eye Res; 2015 Jan; 44():15-35. PubMed ID: 25448922
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Copy number variations of TBK1 in Australian patients with primary open-angle glaucoma.
    Awadalla MS; Fingert JH; Roos BE; Chen S; Holmes R; Graham SL; Chehade M; Galanopolous A; Ridge B; Souzeau E; Zhou T; Siggs OM; Hewitt AW; Mackey DA; Burdon KP; Craig JE
    Am J Ophthalmol; 2015 Jan; 159(1):124-30.e1. PubMed ID: 25284765
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs.
    Zhong X; Gutierrez C; Xue T; Hampton C; Vergara MN; Cao LH; Peters A; Park TS; Zambidis ET; Meyer JS; Gamm DM; Yau KW; Canto-Soler MV
    Nat Commun; 2014 Jun; 5():4047. PubMed ID: 24915161
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.