These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 2488854)

  • 21. The Na+ binding channel of human coagulation proteases: novel insights on the structure and allosteric modulation revealed by molecular surface analysis.
    Silva FP; Antunes OA; de Alencastro RB; De Simone SG
    Biophys Chem; 2006 Feb; 119(3):282-94. PubMed ID: 16288954
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.
    Menegatti E; Bolognesi M; Scalia S; Bortolotti F; Guarneri M; Ascenzi P
    J Pharm Sci; 1986 Dec; 75(12):1171-4. PubMed ID: 3104578
    [TBL] [Abstract][Full Text] [Related]  

  • 23. CoagMDB: a database analysis of missense mutations within four conserved domains in five vitamin K-dependent coagulation serine proteases using a text-mining tool.
    Saunders RE; Perkins SJ
    Hum Mutat; 2008 Mar; 29(3):333-44. PubMed ID: 18058827
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A structural model for the glutamate-specific endopeptidase from Streptomyces griseus that explains substrate specificity.
    Barbosa JA; Garratt RC; Saldanha JW
    FEBS Lett; 1993 Jun; 324(1):45-50. PubMed ID: 8504858
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase.
    Whisstock J; Lesk AM; Carrell R
    Proteins; 1996 Nov; 26(3):288-303. PubMed ID: 8953650
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Comparative binding energy analysis considering multiple receptors: a step toward 3D-QSAR models for multiple targets.
    Murcia M; Morreale A; Ortiz AR
    J Med Chem; 2006 Oct; 49(21):6241-53. PubMed ID: 17034130
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Thrombin-like enzymes from snake venom: Structural characterization and mechanism of action.
    Ullah A; Masood R; Ali I; Ullah K; Ali H; Akbar H; Betzel C
    Int J Biol Macromol; 2018 Jul; 114():788-811. PubMed ID: 29604354
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex.
    Fuentes-Prior P; Iwanaga Y; Huber R; Pagila R; Rumennik G; Seto M; Morser J; Light DR; Bode W
    Nature; 2000 Mar; 404(6777):518-25. PubMed ID: 10761923
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Ligand-receptor 3-D similarity studies using multiple 4-point pharmacophores.
    Mason JS; Cheney DL
    Pac Symp Biocomput; 1999; ():456-67. PubMed ID: 10380219
    [TBL] [Abstract][Full Text] [Related]  

  • 30. S1 subsite in snake venom thrombin-like enzymes: can S1 subsite lipophilicity be used to sort binding affinities of trypsin-like enzymes to small-molecule inhibitors?
    Silva FP; De-Simone SG
    Bioorg Med Chem; 2004 May; 12(10):2571-87. PubMed ID: 15110839
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cloning and molecular modeling of duodenase with respect to evolution of substrate specificity within mammalian serine proteases that have lost a conserved active-site disulfide bond.
    Zamolodchikova TS; Smirnova EV; Andrianov AN; Kashparov IV; Kotsareva OD; Sokolova EA; Ignatov KB; Pemberton AD
    Biochemistry (Mosc); 2005 Jun; 70(6):672-84. PubMed ID: 16038610
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Molecular basis of residue 192 participation in determination of coagulation protease specificity.
    Rezaie AR; Esmon CT
    Eur J Biochem; 1996 Dec; 242(3):477-84. PubMed ID: 9022671
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Comparative molecular modeling analysis of-5-amidinoindole and benzamidine binding to thrombin and trypsin: specific H-bond formation contributes to high 5-amidinoindole potency and selectivity for thrombin and factor Xa.
    Zhou Y; Johnson ME
    J Mol Recognit; 1999; 12(4):235-41. PubMed ID: 10440994
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Interaction of thrombin with antithrombin, heparin cofactor II, and protein C inhibitor.
    Whinna HC; Church FC
    J Protein Chem; 1993 Dec; 12(6):677-88. PubMed ID: 8136018
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Oxyanion-mediated inhibition of serine proteases.
    Presnell SR; Patil GS; Mura C; Jude KM; Conley JM; Bertrand JA; Kam CM; Powers JC; Williams LD
    Biochemistry; 1998 Dec; 37(48):17068-81. PubMed ID: 9836602
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The role of the insertion loop around tryptophan 148 in tthe activity of thrombin.
    DiBella EE; Scheraga HA
    Biochemistry; 1996 Apr; 35(14):4427-33. PubMed ID: 8605192
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Selective inhibition of trypsin by (2R,4R)-4-phenyl-1-[Nalpha-(7- methoxy-2-naphthalenesulfonyl)-L-arginyl]-2-piperidinecarboxylic acid.
    Hijikata-Okunomiya A; Tamao Y; Kikumoto R; Okamoto S
    J Biol Chem; 2000 Jun; 275(25):18995-9. PubMed ID: 10748093
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.
    Katz BA; Mackman R; Luong C; Radika K; Martelli A; Sprengeler PA; Wang J; Chan H; Wong L
    Chem Biol; 2000 Apr; 7(4):299-312. PubMed ID: 10779411
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A novel venombin B from agkistrodon contortrix contortrix: evidence for recognition properties in the surface around the primary specificity pocket different from thrombin.
    Amiconi G; Amoresano A; Boumis G; Brancaccio A; De Cristofaro R; De Pascalis A; Di Girolamo S; Maras B; Scaloni A
    Biochemistry; 2000 Aug; 39(33):10294-308. PubMed ID: 10956019
    [TBL] [Abstract][Full Text] [Related]  

  • 40. How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin.
    Sandner A; Ngo K; Schiebel J; Pizarroso AIM; Schmidt L; Wenzel B; Steinmetzer T; Ostermann A; Heine A; Klebe G
    J Med Chem; 2021 Feb; 64(3):1611-1625. PubMed ID: 33471524
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.