BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

842 related articles for article (PubMed ID: 24896180)

  • 1. BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.
    Bhatia V; Barroso SI; García-Rubio ML; Tumini E; Herrera-Moyano E; Aguilera A
    Nature; 2014 Jul; 511(7509):362-5. PubMed ID: 24896180
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased chemosensitivity via BRCA2-independent DNA damage in DSS1- and PCID2-depleted breast carcinomas.
    Gondo N; Sakai Y; Zhang Z; Hato Y; Kuzushima K; Phimsen S; Kawashima Y; Kuroda M; Suzuki M; Okada S; Iwata H; Toyama T; Rezano A; Kuwahara K
    Lab Invest; 2021 Aug; 101(8):1048-1059. PubMed ID: 34031538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability.
    Salas-Armenteros I; Pérez-Calero C; Bayona-Feliu A; Tumini E; Luna R; Aguilera A
    EMBO J; 2017 Dec; 36(23):3532-3547. PubMed ID: 29074626
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.
    Domínguez-Sánchez MS; Barroso S; Gómez-González B; Luna R; Aguilera A
    PLoS Genet; 2011 Dec; 7(12):e1002386. PubMed ID: 22144908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export.
    Jani D; Lutz S; Hurt E; Laskey RA; Stewart M; Wickramasinghe VO
    Nucleic Acids Res; 2012 May; 40(10):4562-73. PubMed ID: 22307388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair.
    Evangelista FM; Maglott-Roth A; Stierle M; Brino L; Soutoglou E; Tora L
    J Cell Biol; 2018 Oct; 217(10):3382-3397. PubMed ID: 30054449
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The human TREX-2 complex is stably associated with the nuclear pore basket.
    Umlauf D; Bonnet J; Waharte F; Fournier M; Stierle M; Fischer B; Brino L; Devys D; Tora L
    J Cell Sci; 2013 Jun; 126(Pt 12):2656-67. PubMed ID: 23591820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The interface between transcription and mRNP export: from THO to THSC/TREX-2.
    Rondón AG; Jimeno S; Aguilera A
    Biochim Biophys Acta; 2010 Aug; 1799(8):533-8. PubMed ID: 20601280
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.
    González-Aguilera C; Tous C; Gómez-González B; Huertas P; Luna R; Aguilera A
    Mol Biol Cell; 2008 Oct; 19(10):4310-8. PubMed ID: 18667528
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery.
    Faza MB; Kemmler S; Jimeno S; González-Aguilera C; Aguilera A; Hurt E; Panse VG
    J Cell Biol; 2009 Mar; 184(6):833-46. PubMed ID: 19289793
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sem1: a versatile "molecular glue"?
    Faza MB; Kemmler S; Panse VG
    Nucleus; 2010; 1(1):12-7. PubMed ID: 21327099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export.
    Viphakone N; Hautbergue GM; Walsh M; Chang CT; Holland A; Folco EG; Reed R; Wilson SA
    Nat Commun; 2012; 3():1006. PubMed ID: 22893130
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human TREX2 components PCID2 and centrin 2, but not ENY2, have distinct functions in protein export and co-localize to the centrosome.
    Cunningham CN; Schmidt CA; Schramm NJ; Gaylord MR; Resendes KK
    Exp Cell Res; 2014 Jan; 320(2):209-18. PubMed ID: 24291146
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1.
    Nguyen HD; Yadav T; Giri S; Saez B; Graubert TA; Zou L
    Mol Cell; 2017 Mar; 65(5):832-847.e4. PubMed ID: 28257700
    [TBL] [Abstract][Full Text] [Related]  

  • 15. THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans.
    Zheleva A; Camino LP; Fernández-Fernández N; García-Rubio M; Askjaer P; García-Muse T; Aguilera A
    J Cell Sci; 2021 Oct; 134(20):. PubMed ID: 34553761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability.
    Hamperl S; Cimprich KA
    DNA Repair (Amst); 2014 Jul; 19():84-94. PubMed ID: 24746923
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability.
    Costantino L; Koshland D
    Mol Cell; 2018 Aug; 71(4):487-497.e3. PubMed ID: 30078723
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Germinal Center B-Cell-Associated Nuclear Protein (GANP) Involved in RNA Metabolism for B Cell Maturation.
    Sakaguchi N; Maeda K
    Adv Immunol; 2016; 131():135-86. PubMed ID: 27235683
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability.
    Santos-Pereira JM; Herrero AB; García-Rubio ML; Marín A; Moreno S; Aguilera A
    Genes Dev; 2013 Nov; 27(22):2445-58. PubMed ID: 24240235
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.
    Boyne JR; Colgan KJ; Whitehouse A
    PLoS Pathog; 2008 Oct; 4(10):e1000194. PubMed ID: 18974867
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 43.