BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 24901250)

  • 1. The self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation.
    Wang J; Tucker-Kellogg L; Ng IC; Jia R; Thiagarajan PS; White JK; Yu H
    PLoS Comput Biol; 2014 Jun; 10(6):e1003573. PubMed ID: 24901250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway.
    Bu S; Kapanadze B; Hsu T; Trojanowska M
    J Biol Chem; 2008 Jul; 283(28):19593-602. PubMed ID: 18482992
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.
    Lin X; Duan X; Liang YY; Su Y; Wrighton KH; Long J; Hu M; Davis CM; Wang J; Brunicardi FC; Shi Y; Chen YG; Meng A; Feng XH
    Cell; 2006 Jun; 125(5):915-28. PubMed ID: 16751101
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The long-noncoding RNA MALAT1 regulates TGF-β/Smad signaling through formation of a lncRNA-protein complex with Smads, SETD2 and PPM1A in hepatic cells.
    Zhang J; Han C; Song K; Chen W; Ungerleider N; Yao L; Ma W; Wu T
    PLoS One; 2020; 15(1):e0228160. PubMed ID: 31995604
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-β/Smad signaling pathway.
    Geng J; Fan J; Ouyang Q; Zhang X; Zhang X; Yu J; Xu Z; Li Q; Yao X; Liu X; Zheng J
    Oncotarget; 2014 Jul; 5(14):5700-11. PubMed ID: 25026293
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a Smad phosphatase.
    Hill CS
    ACS Chem Biol; 2006 Jul; 1(6):346-8. PubMed ID: 17163769
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway.
    Duan X; Liang YY; Feng XH; Lin X
    J Biol Chem; 2006 Dec; 281(48):36526-32. PubMed ID: 16931515
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.
    Yan X; Liao H; Cheng M; Shi X; Lin X; Feng XH; Chen YG
    J Biol Chem; 2016 Jan; 291(1):382-92. PubMed ID: 26555259
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Termination of TGF-beta superfamily signaling through SMAD dephosphorylation--a functional genomic view.
    Lin X; Chen Y; Meng A; Feng X
    J Genet Genomics; 2007 Jan; 34(1):1-9. PubMed ID: 17469772
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TRIM59 inhibits PPM1A through ubiquitination and activates TGF-β/Smad signaling to promote the invasion of ectopic endometrial stromal cells in endometriosis.
    Wang F; Wang H; Sun L; Niu C; Xu J
    Am J Physiol Cell Physiol; 2020 Aug; 319(2):C392-C401. PubMed ID: 32348176
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.
    Nicklas D; Saiz L
    J R Soc Interface; 2013 Sep; 10(86):20130363. PubMed ID: 23804438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The oncoprotein c-ski functions as a direct antagonist of the transforming growth factor-{beta} type I receptor.
    Ferrand N; Atfi A; Prunier C
    Cancer Res; 2010 Nov; 70(21):8457-66. PubMed ID: 20959473
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.
    Bourgeois B; Gilquin B; Tellier-Lebègue C; Östlund C; Wu W; Pérez J; El Hage P; Lallemand F; Worman HJ; Zinn-Justin S
    Sci Signal; 2013 Jun; 6(280):ra49. PubMed ID: 23779087
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8.
    van den Bosch MH; Blom AB; van Lent PL; van Beuningen HM; Blaney Davidson EN; van der Kraan PM; van den Berg WB
    Cell Signal; 2014 May; 26(5):951-8. PubMed ID: 24463008
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of c-myc repression coincides with ovarian cancer resistance to transforming growth factor beta growth arrest independent of transforming growth factor beta/Smad signaling.
    Baldwin RL; Tran H; Karlan BY
    Cancer Res; 2003 Mar; 63(6):1413-9. PubMed ID: 12649207
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Echinococcus multilocularis: molecular characterization of EmSmadE, a novel BR-Smad involved in TGF-β and BMP signaling.
    Epping K; Brehm K
    Exp Parasitol; 2011 Oct; 129(2):85-94. PubMed ID: 21802416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor.
    Ulloa L; Tabibzadeh S
    J Biol Chem; 2001 Jun; 276(24):21397-404. PubMed ID: 11278746
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mesenchyme homeobox 1 mediates transforming growth factor-β (TGF-β)-induced smooth muscle cell differentiation from mouse mesenchymal progenitors.
    Dong K; Guo X; Chen W; Hsu AC; Shao Q; Chen JF; Chen SY
    J Biol Chem; 2018 Jun; 293(22):8712-8719. PubMed ID: 29678882
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein phosphatase magnesium-dependent 1A-mediated inhibition of BMP signaling is independent of Smad dephosphorylation.
    Kokabu S; Nojima J; Kanomata K; Ohte S; Yoda T; Fukuda T; Katagiri T
    J Bone Miner Res; 2010 Mar; 25(3):653-60. PubMed ID: 19594322
    [TBL] [Abstract][Full Text] [Related]  

  • 20. miR-522 stimulates TGF-β/Smad signaling pathway and promotes osteosarcoma tumorigenesis by targeting PPM1A.
    Xu X; Liu M
    J Cell Biochem; 2019 Oct; 120(10):18425-18434. PubMed ID: 31190351
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.