These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 24901470)

  • 1. Acute sterol o-acyltransferase 2 (SOAT2) knockdown rapidly mobilizes hepatic cholesterol for fecal excretion.
    Marshall SM; Gromovsky AD; Kelley KL; Davis MA; Wilson MD; Lee RG; Crooke RM; Graham MJ; Rudel LL; Brown JM; Temel RE
    PLoS One; 2014; 9(6):e98953. PubMed ID: 24901470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss.
    Brown JM; Bell TA; Alger HM; Sawyer JK; Smith TL; Kelley K; Shah R; Wilson MD; Davis MA; Lee RG; Graham MJ; Crooke RM; Rudel LL
    J Biol Chem; 2008 Apr; 283(16):10522-34. PubMed ID: 18281279
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cholesterol esters (CE) derived from hepatic sterol O-acyltransferase 2 (SOAT2) are associated with more atherosclerosis than CE from intestinal SOAT2.
    Zhang J; Sawyer JK; Marshall SM; Kelley KL; Davis MA; Wilson MD; Brown JM; Rudel LL
    Circ Res; 2014 Oct; 115(10):826-33. PubMed ID: 25239141
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver.
    Lopez AM; Posey KS; Turley SD
    Biochem Biophys Res Commun; 2014 Nov; 454(1):162-6. PubMed ID: 25450374
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sterol O-Acyltransferase 2-Driven Cholesterol Esterification Opposes Liver X Receptor-Stimulated Fecal Neutral Sterol Loss.
    Warrier M; Zhang J; Bura K; Kelley K; Wilson MD; Rudel LL; Brown JM
    Lipids; 2016 Feb; 51(2):151-7. PubMed ID: 26729489
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function.
    Lopez AM; Jones RD; Repa JJ; Turley SD
    Am J Physiol Gastrointest Liver Physiol; 2018 Oct; 315(4):G454-G463. PubMed ID: 29878847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Liver-specific inhibition of acyl-coenzyme a:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice.
    Bell TA; Brown JM; Graham MJ; Lemonidis KM; Crooke RM; Rudel LL
    Arterioscler Thromb Vasc Biol; 2006 Aug; 26(8):1814-20. PubMed ID: 16675724
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models.
    Ohshiro T; Ohtawa M; Nagamitsu T; Matsuda D; Yagyu H; Davis MA; Rudel LL; Ishibashi S; Tomoda H
    J Pharmacol Exp Ther; 2015 Nov; 355(2):299-307. PubMed ID: 26338984
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice.
    Lopez AM; Chuang JC; Posey KS; Ohshiro T; Tomoda H; Rudel LL; Turley SD
    J Pharmacol Exp Ther; 2015 Nov; 355(2):159-67. PubMed ID: 26283692
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.
    Alger HM; Brown JM; Sawyer JK; Kelley KL; Shah R; Wilson MD; Willingham MC; Rudel LL
    J Biol Chem; 2010 May; 285(19):14267-74. PubMed ID: 20231283
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted Knockdown of Hepatic SOAT2 With Antisense Oligonucleotides Stabilizes Atherosclerotic Plaque in ApoB100-only LDLr-/- Mice.
    Melchior JT; Olson JD; Kelley KL; Wilson MD; Sawyer JK; Link KM; Rudel LL
    Arterioscler Thromb Vasc Biol; 2015 Sep; 35(9):1920-7. PubMed ID: 26229140
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of SCP-2/SCP-x gene ablation and dietary cholesterol on hepatic lipid accumulation.
    Klipsic D; Landrock D; Martin GG; McIntosh AL; Landrock KK; Mackie JT; Schroeder F; Kier AB
    Am J Physiol Gastrointest Liver Physiol; 2015 Sep; 309(5):G387-99. PubMed ID: 26113298
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice.
    Nijstad N; Gautier T; Briand F; Rader DJ; Tietge UJ
    Gastroenterology; 2011 Mar; 140(3):1043-51. PubMed ID: 21134376
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse.
    Lopez AM; Chuang JC; Turley SD
    Steroids; 2018 Feb; 130():7-14. PubMed ID: 29246491
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice.
    Pramfalk C; Ahmed O; Pedrelli M; Minniti ME; Luquet S; Denis RG; Olin M; Härdfeldt J; Vedin LL; Steffensen KR; Rydén M; Hodson L; Eriksson M; Parini P
    J Intern Med; 2022 Aug; 292(2):296-307. PubMed ID: 34982494
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice.
    Ahmed O; Pramfalk C; Pedrelli M; Olin M; Steffensen KR; Eriksson M; Parini P
    Dig Liver Dis; 2019 Jul; 51(7):1016-1022. PubMed ID: 30630736
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Plasma FA composition in familial LCAT deficiency indicates SOAT2-derived cholesteryl ester formation in humans.
    Pavanello C; Ossoli A; Strazzella A; Risè P; Veglia F; Lhomme M; Parini P; Calabresi L
    J Lipid Res; 2022 Jul; 63(7):100232. PubMed ID: 35598637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential.
    Lee RG; Kelley KL; Sawyer JK; Farese RV; Parks JS; Rudel LL
    Circ Res; 2004 Nov; 95(10):998-1004. PubMed ID: 15486318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Liver ABCA1 deletion in LDLrKO mice does not impair macrophage reverse cholesterol transport or exacerbate atherogenesis.
    Bi X; Zhu X; Duong M; Boudyguina EY; Wilson MD; Gebre AK; Parks JS
    Arterioscler Thromb Vasc Biol; 2013 Oct; 33(10):2288-96. PubMed ID: 23814116
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual action of neutral sphingomyelinase on rat hepatocytes: activation of cholesteryl ester metabolism and biliary cholesterol secretion and inhibition of VLDL secretion.
    Liza M; Chico Y; Fresnedo O; Ochoa B
    Lipids; 2003 Jan; 38(1):53-63. PubMed ID: 12669820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.