BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1018 related articles for article (PubMed ID: 24904965)

  • 1. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
    Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases.
    Khadka DB; Tran GH; Shin S; Nguyen HT; Cao HT; Zhao C; Jin Y; Van HT; Chau MV; Kwon Y; Le TN; Cho WJ
    Eur J Med Chem; 2015 Oct; 103():69-79. PubMed ID: 26334499
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
    Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition.
    Khadka DB; Woo H; Yang SH; Zhao C; Jin Y; Le TN; Kwon Y; Cho WJ
    Eur J Med Chem; 2015 Mar; 92():583-607. PubMed ID: 25613224
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors.
    Yao BL; Mai YW; Chen SB; Xie HT; Yao PF; Ou TM; Tan JH; Wang HG; Li D; Huang SL; Gu LQ; Huang ZS
    Eur J Med Chem; 2015 Mar; 92():540-53. PubMed ID: 25599951
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
    Thapa P; Kadayat TM; Park S; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Bioorg Chem; 2016 Jun; 66():145-59. PubMed ID: 27174797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents.
    Chen TC; Wu CL; Lee CC; Chen CL; Yu DS; Huang HS
    Eur J Med Chem; 2015 Oct; 103():615-27. PubMed ID: 25799376
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
    Karki R; Jun KY; Kadayat TM; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Eur J Med Chem; 2016 May; 113():228-45. PubMed ID: 26945111
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L; Marzaro G; Ferrarese A; Gia O; Chilin A
    Eur J Med Chem; 2014 Apr; 77():103-9. PubMed ID: 24631729
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity.
    Abdel-Aziz M; Park SE; Abuo-Rahma Gel-D; Sayed MA; Kwon Y
    Eur J Med Chem; 2013 Nov; 69():427-38. PubMed ID: 24090914
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of novel ellipticines as potential anti-cancer agents.
    Deane FM; O'Sullivan EC; Maguire AR; Gilbert J; Sakoff JA; McCluskey A; McCarthy FO
    Org Biomol Chem; 2013 Feb; 11(8):1334-44. PubMed ID: 23314103
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
    Kadayat TM; Song C; Shin S; Magar TB; Bist G; Shrestha A; Thapa P; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Jul; 23(13):3499-512. PubMed ID: 26022080
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Thapa U; Thapa P; Karki R; Yun M; Choi JH; Jahng Y; Lee E; Jeon KH; Na Y; Ha EM; Cho WJ; Kwon Y; Lee ES
    Eur J Med Chem; 2011 Aug; 46(8):3201-9. PubMed ID: 21601964
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study.
    Van HT; Khadka DB; Yang SH; Le TN; Cho SH; Zhao C; Lee IS; Kwon Y; Lee KT; Kim YC; Cho WJ
    Bioorg Med Chem; 2011 Sep; 19(18):5311-20. PubMed ID: 21873069
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents.
    Genès C; Lenglet G; Depauw S; Nhili R; Prado S; David-Cordonnier MH; Michel S; Tillequin F; Porée FH
    Eur J Med Chem; 2011 Jun; 46(6):2117-31. PubMed ID: 21435753
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors.
    Zhang X; Wang R; Zhao L; Lu N; Wang J; You Q; Li Z; Guo Q
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1276-81. PubMed ID: 22079759
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones.
    Ahn G; Schifano-Faux N; Goossens JF; Baldeyrou B; Couture A; Grandclaudon P; Lansiaux A; Ryckebusch A
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2259-63. PubMed ID: 21439821
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
    Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
    J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
    Zhou Y; Xu X; Sun Y; Wang H; Sun H; You Q
    Bioorg Med Chem Lett; 2013 May; 23(10):2974-8. PubMed ID: 23566520
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors.
    Khadka DB; Park S; Jin Y; Han J; Kwon Y; Cho WJ
    Eur J Med Chem; 2018 Jan; 143():200-215. PubMed ID: 29174815
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 51.