BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 24910438)

  • 1. The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin.
    Quick-Cleveland J; Jacob JP; Weitz SH; Shoffner G; Senturia R; Guo F
    Cell Rep; 2014 Jun; 7(6):1994-2005. PubMed ID: 24910438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity.
    Hines JP; Smith AT; Jacob JP; Lukat-Rodgers GS; Barr I; Rodgers KR; Guo F; Burstyn JN
    J Biol Inorg Chem; 2016 Dec; 21(8):1021-1035. PubMed ID: 27766492
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The core microprocessor component DiGeorge syndrome critical region 8 (DGCR8) is a nonspecific RNA-binding protein.
    Roth BM; Ishimaru D; Hennig M
    J Biol Chem; 2013 Sep; 288(37):26785-99. PubMed ID: 23893406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs.
    Partin AC; Ngo TD; Herrell E; Jeong BC; Hon G; Nam Y
    Nat Commun; 2017 Nov; 8(1):1737. PubMed ID: 29170488
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Select amino acids in DGCR8 are essential for the UGU-pri-miRNA interaction and processing.
    Dang TL; Le CT; Le MN; Nguyen TD; Nguyen TL; Bao S; Li S; Nguyen TA
    Commun Biol; 2020 Jul; 3(1):344. PubMed ID: 32620823
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Basis for pri-miRNA Recognition by Drosha.
    Jin W; Wang J; Liu CP; Wang HW; Xu RM
    Mol Cell; 2020 May; 78(3):423-433.e5. PubMed ID: 32220645
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures.
    Faller M; Toso D; Matsunaga M; Atanasov I; Senturia R; Chen Y; Zhou ZH; Guo F
    RNA; 2010 Aug; 16(8):1570-83. PubMed ID: 20558544
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Processing of microRNA primary transcripts requires heme in mammalian cells.
    Weitz SH; Gong M; Barr I; Weiss S; Guo F
    Proc Natl Acad Sci U S A; 2014 Feb; 111(5):1861-6. PubMed ID: 24449907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing.
    Barr I; Smith AT; Chen Y; Senturia R; Burstyn JN; Guo F
    Proc Natl Acad Sci U S A; 2012 Feb; 109(6):1919-24. PubMed ID: 22308374
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DGCR8-dependent efficient pri-miRNA processing of human pri-miR-9-2.
    Nogami M; Miyamoto K; Hayakawa-Yano Y; Nakanishi A; Yano M; Okano H
    J Biol Chem; 2021; 296():100409. PubMed ID: 33581109
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting.
    Herbert KM; Sarkar SK; Mills M; Delgado De la Herran HC; Neuman KC; Steitz JA
    RNA; 2016 Feb; 22(2):175-83. PubMed ID: 26683315
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heme is involved in microRNA processing.
    Faller M; Matsunaga M; Yin S; Loo JA; Guo F
    Nat Struct Mol Biol; 2007 Jan; 14(1):23-9. PubMed ID: 17159994
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N6-methyladenosine marks primary microRNAs for processing.
    Alarcón CR; Lee H; Goodarzi H; Halberg N; Tavazoie SF
    Nature; 2015 Mar; 519(7544):482-5. PubMed ID: 25799998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
    Partin AC; Zhang K; Jeong BC; Herrell E; Li S; Chiu W; Nam Y
    Mol Cell; 2020 May; 78(3):411-422.e4. PubMed ID: 32220646
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deformability in the cleavage site of primary microRNA is not sensed by the double-stranded RNA binding domains in the microprocessor component DGCR8.
    Quarles KA; Chadalavada D; Showalter SA
    Proteins; 2015 Jun; 83(6):1165-79. PubMed ID: 25851436
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Primary microRNA processing assay reconstituted using recombinant Drosha and DGCR8.
    Barr I; Guo F
    Methods Mol Biol; 2014; 1095():73-86. PubMed ID: 24166303
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing.
    Yeom KH; Lee Y; Han J; Suh MR; Kim VN
    Nucleic Acids Res; 2006; 34(16):4622-9. PubMed ID: 16963499
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional Anatomy of the Human Microprocessor.
    Nguyen TA; Jo MH; Choi YG; Park J; Kwon SC; Hohng S; Kim VN; Woo JS
    Cell; 2015 Jun; 161(6):1374-87. PubMed ID: 26027739
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A central role for the primary microRNA stem in guiding the position and efficiency of Drosha processing of a viral pri-miRNA.
    Burke JM; Kelenis DP; Kincaid RP; Sullivan CS
    RNA; 2014 Jul; 20(7):1068-77. PubMed ID: 24854622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The kinase ABL phosphorylates the microprocessor subunit DGCR8 to stimulate primary microRNA processing in response to DNA damage.
    Tu CC; Zhong Y; Nguyen L; Tsai A; Sridevi P; Tarn WY; Wang JY
    Sci Signal; 2015 Jun; 8(383):ra64. PubMed ID: 26126715
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.