BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 24912600)

  • 1. Translational read-through as an alternative approach for ocular gene therapy of retinal dystrophies caused by in-frame nonsense mutations.
    Nagel-Wolfrum K; Möller F; Penner I; Wolfrum U
    Vis Neurosci; 2014 Sep; 31(4-5):309-16. PubMed ID: 24912600
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation.
    Goldmann T; Overlack N; Möller F; Belakhov V; van Wyk M; Baasov T; Wolfrum U; Nagel-Wolfrum K
    EMBO Mol Med; 2012 Nov; 4(11):1186-99. PubMed ID: 23027640
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Strategies against Nonsense: Oxadiazoles as Translational Readthrough-Inducing Drugs (TRIDs).
    Campofelice A; Lentini L; Di Leonardo A; Melfi R; Tutone M; Pace A; Pibiri I
    Int J Mol Sci; 2019 Jul; 20(13):. PubMed ID: 31284579
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ataluren for the Treatment of Usher Syndrome 2A Caused by Nonsense Mutations.
    Samanta A; Stingl K; Kohl S; Ries J; Linnert J; Nagel-Wolfrum K
    Int J Mol Sci; 2019 Dec; 20(24):. PubMed ID: 31842393
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rescue of melanocortin 4 receptor (MC4R) nonsense mutations by aminoglycoside-mediated read-through.
    Brumm H; Mühlhaus J; Bolze F; Scherag S; Hinney A; Hebebrand J; Wiegand S; Klingenspor M; Grüters A; Krude H; Biebermann H
    Obesity (Silver Spring); 2012 May; 20(5):1074-81. PubMed ID: 21738238
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting Nonsense Mutations in Diseases with Translational Read-Through-Inducing Drugs (TRIDs).
    Nagel-Wolfrum K; Möller F; Penner I; Baasov T; Wolfrum U
    BioDrugs; 2016 Apr; 30(2):49-74. PubMed ID: 26886021
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmaceuticals Promoting Premature Termination Codon Readthrough: Progress in Development.
    Li S; Li J; Shi W; Nie Z; Zhang S; Ma F; Hu J; Chen J; Li P; Xie X
    Biomolecules; 2023 Jun; 13(6):. PubMed ID: 37371567
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmaceuticals targeting nonsense mutations in genetic diseases: progress in development.
    Rowe SM; Clancy JP
    BioDrugs; 2009; 23(3):165-74. PubMed ID: 19627168
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C.
    Goldmann T; Overlack N; Wolfrum U; Nagel-Wolfrum K
    Hum Gene Ther; 2011 May; 22(5):537-47. PubMed ID: 21235327
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cancer syndromes and therapy by stop-codon readthrough.
    Bordeira-Carriço R; Pêgo AP; Santos M; Oliveira C
    Trends Mol Med; 2012 Nov; 18(11):667-78. PubMed ID: 23044248
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ataluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms.
    Ng MY; Li H; Ghelfi MD; Goldman YE; Cooperman BS
    Proc Natl Acad Sci U S A; 2021 Jan; 118(2):. PubMed ID: 33414181
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives.
    Pibiri I; Lentini L; Melfi R; Gallucci G; Pace A; Spinello A; Barone G; Di Leonardo A
    Eur J Med Chem; 2015 Aug; 101():236-44. PubMed ID: 26142488
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism and evidence of nonsense suppression therapy for genetic eye disorders.
    Richardson R; Smart M; Tracey-White D; Webster AR; Moosajee M
    Exp Eye Res; 2017 Feb; 155():24-37. PubMed ID: 28065590
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Read-through strategies for suppression of nonsense mutations in Duchenne/ Becker muscular dystrophy: aminoglycosides and ataluren (PTC124).
    Finkel RS
    J Child Neurol; 2010 Sep; 25(9):1158-64. PubMed ID: 20519671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aminoglycosides, but not PTC124 (Ataluren), rescue nonsense mutations in the leptin receptor and in luciferase reporter genes.
    Bolze F; Mocek S; Zimmermann A; Klingenspor M
    Sci Rep; 2017 Apr; 7(1):1020. PubMed ID: 28432296
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Clinically relevant aminoglycosides can suppress disease-associated premature stop mutations in the IDUA and P53 cDNAs in a mammalian translation system.
    Keeling KM; Bedwell DM
    J Mol Med (Berl); 2002 Jun; 80(6):367-76. PubMed ID: 12072912
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PTC124 targets genetic disorders caused by nonsense mutations.
    Welch EM; Barton ER; Zhuo J; Tomizawa Y; Friesen WJ; Trifillis P; Paushkin S; Patel M; Trotta CR; Hwang S; Wilde RG; Karp G; Takasugi J; Chen G; Jones S; Ren H; Moon YC; Corson D; Turpoff AA; Campbell JA; Conn MM; Khan A; Almstead NG; Hedrick J; Mollin A; Risher N; Weetall M; Yeh S; Branstrom AA; Colacino JM; Babiak J; Ju WD; Hirawat S; Northcutt VJ; Miller LL; Spatrick P; He F; Kawana M; Feng H; Jacobson A; Peltz SW; Sweeney HL
    Nature; 2007 May; 447(7140):87-91. PubMed ID: 17450125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro read-through of phenylalanine hydroxylase (PAH) nonsense mutations using aminoglycosides: a potential therapy for phenylketonuria.
    Ho G; Reichardt J; Christodoulou J
    J Inherit Metab Dis; 2013 Nov; 36(6):955-9. PubMed ID: 23532445
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Beneficial read-through of a USH1C nonsense mutation by designed aminoglycoside NB30 in the retina.
    Goldmann T; Rebibo-Sabbah A; Overlack N; Nudelman I; Belakhov V; Baasov T; Ben-Yosef T; Wolfrum U; Nagel-Wolfrum K
    Invest Ophthalmol Vis Sci; 2010 Dec; 51(12):6671-80. PubMed ID: 20671281
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aminoglycoside-induced translational read-through in disease: overcoming nonsense mutations by pharmacogenetic therapy.
    Zingman LV; Park S; Olson TM; Alekseev AE; Terzic A
    Clin Pharmacol Ther; 2007 Jan; 81(1):99-103. PubMed ID: 17186006
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.