These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 24915089)

  • 1. Characterization, crystallization and preliminary X-ray crystallographic analysis of the Uba5 fragment necessary for high-efficiency activation of Ufm1.
    Xie S
    Acta Crystallogr F Struct Biol Commun; 2014 Jun; 70(Pt 6):765-8. PubMed ID: 24915089
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization, crystallization and preliminary X-ray crystallographic analysis of the human Uba5 C-terminus-Ufc1 complex.
    Xie S
    Acta Crystallogr F Struct Biol Commun; 2014 Aug; 70(Pt 8):1093-7. PubMed ID: 25084390
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel insights into the interaction of UBA5 with UFM1 via a UFM1-interacting sequence.
    Padala P; Oweis W; Mashahreh B; Soudah N; Cohen-Kfir E; Todd EA; Berndsen CE; Wiener R
    Sci Rep; 2017 Mar; 7(1):508. PubMed ID: 28360427
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation.
    Habisov S; Huber J; Ichimura Y; Akutsu M; Rogova N; Loehr F; McEwan DG; Johansen T; Dikic I; Doetsch V; Komatsu M; Rogov VV; Kirkin V
    J Biol Chem; 2016 Apr; 291(17):9025-41. PubMed ID: 26929408
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation.
    Soudah N; Padala P; Hassouna F; Kumar M; Mashahreh B; Lebedev AA; Isupov MN; Cohen-Kfir E; Wiener R
    J Mol Biol; 2019 Feb; 431(3):463-478. PubMed ID: 30412706
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trans-binding of UFM1 to UBA5 stimulates UBA5 homodimerization and ATP binding.
    Mashahreh B; Hassouna F; Soudah N; Cohen-Kfir E; Strulovich R; Haitin Y; Wiener R
    FASEB J; 2018 May; 32(5):2794-2802. PubMed ID: 29295865
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic study of Uba5 enzyme and the Ufm1 conjugation pathway.
    Gavin JM; Hoar K; Xu Q; Ma J; Lin Y; Chen J; Chen W; Bruzzese FJ; Harrison S; Mallender WD; Bump NJ; Sintchak MD; Bence NF; Li P; Dick LR; Gould AE; Chen JJ
    J Biol Chem; 2014 Aug; 289(33):22648-22658. PubMed ID: 24966333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1.
    Wesch N; Löhr F; Rogova N; Dötsch V; Rogov VV
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34299007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway.
    Liu G; Forouhar F; Eletsky A; Atreya HS; Aramini JM; Xiao R; Huang YJ; Abashidze M; Seetharaman J; Liu J; Rost B; Acton T; Montelione GT; Hunt JF; Szyperski T
    J Struct Funct Genomics; 2009 Apr; 10(2):127-36. PubMed ID: 19101823
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.
    Bacik JP; Walker JR; Ali M; Schimmer AD; Dhe-Paganon S
    J Biol Chem; 2010 Jun; 285(26):20273-80. PubMed ID: 20368332
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trans-Binding Mechanism of Ubiquitin-like Protein Activation Revealed by a UBA5-UFM1 Complex.
    Oweis W; Padala P; Hassouna F; Cohen-Kfir E; Gibbs DR; Todd EA; Berndsen CE; Wiener R
    Cell Rep; 2016 Sep; 16(12):3113-3120. PubMed ID: 27653677
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure and dynamics of UBA5-UFM1 complex formation showing new insights in the UBA5 activation mechanism.
    Fuchs S; Kikhney AG; Schubert R; Kaiser C; Liebau E; Svergun DI; Betzel C; Perbandt M
    J Struct Biol; 2021 Dec; 213(4):107796. PubMed ID: 34508858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of UBA5 in Cells Mimics the Phenotype of Cells Lacking UBA5.
    Kumari S; Banerjee S; Kumar M; Hayashi A; Solaimuthu B; Cohen-Kfir E; Shaul YD; Rouvinski A; Wiener R
    Int J Mol Sci; 2022 Jul; 23(13):. PubMed ID: 35806453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UBA5 Mutations Cause a New Form of Autosomal Recessive Cerebellar Ataxia.
    Duan R; Shi Y; Yu L; Zhang G; Li J; Lin Y; Guo J; Wang J; Shen L; Jiang H; Wang G; Tang B
    PLoS One; 2016; 11(2):e0149039. PubMed ID: 26872069
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis for UFM1 transfer from UBA5 to UFC1.
    Kumar M; Padala P; Fahoum J; Hassouna F; Tsaban T; Zoltsman G; Banerjee S; Cohen-Kfir E; Dessau M; Rosenzweig R; Isupov MN; Schueler-Furman O; Wiener R
    Nat Commun; 2021 Sep; 12(1):5708. PubMed ID: 34588452
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression, crystallization and preliminary crystallographic study of the C-terminal half of nsp2 from SARS coronavirus.
    Li Y; Ren Z; Bao Z; Ming Z; Li X
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2011 Jul; 67(Pt 7):790-3. PubMed ID: 21795795
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice.
    Tatsumi K; Yamamoto-Mukai H; Shimizu R; Waguri S; Sou YS; Sakamoto A; Taya C; Shitara H; Hara T; Chung CH; Tanaka K; Yamamoto M; Komatsu M
    Nat Commun; 2011 Feb; 2():181. PubMed ID: 21304510
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A selective inhibitor of the UFM1-activating enzyme, UBA5.
    da Silva SR; Paiva SL; Bancerz M; Geletu M; Lewis AM; Chen J; Cai Y; Lukkarila JL; Li H; Gunning PT
    Bioorg Med Chem Lett; 2016 Sep; 26(18):4542-4547. PubMed ID: 27520940
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of Ufc1, the Ufm1-conjugating enzyme.
    Mizushima T; Tatsumi K; Ozaki Y; Kawakami T; Suzuki A; Ogasahara K; Komatsu M; Kominami E; Tanaka K; Yamane T
    Biochem Biophys Res Commun; 2007 Nov; 362(4):1079-84. PubMed ID: 17825256
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystallization and preliminary X-ray crystallographic analysis of YfcM: an important factor for EF-P hydroxylation.
    Kobayashi K; Suzuki T; Dohmae N; Ishitani R; Nureki O
    Acta Crystallogr F Struct Biol Commun; 2014 Sep; 70(Pt 9):1236-9. PubMed ID: 25195899
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.