46 related articles for article (PubMed ID: 24915467)
1. Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D.
Krześniak M; Zajkowicz A; Matuszczyk I; Rusin M
Mech Ageing Dev; 2014 Jul; 139():11-21. PubMed ID: 24915467
[TBL] [Abstract][Full Text] [Related]
2. Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes.
Łasut-Szyszka B; Gdowicz-Kłosok A; Małachowska B; Krześniak M; Będzińska A; Gawin M; Pietrowska M; Rusin M
Chem Biol Interact; 2024 Apr; 392():110946. PubMed ID: 38460933
[TBL] [Abstract][Full Text] [Related]
3. Progeria, rapamycin and normal aging: recent breakthrough.
Blagosklonny MV
Aging (Albany NY); 2011 Jul; 3(7):685-91. PubMed ID: 21743107
[TBL] [Abstract][Full Text] [Related]
4. Forever young? Exploring the link between rapamycin, longevity and cancer.
Van Meter M; Seluanov A; Gorbunova V
Cell Cycle; 2012 Dec; 11(23):4296-7. PubMed ID: 23152185
[No Abstract] [Full Text] [Related]
5. Organosulfur Compound Identified from Striga angustifolia (D. Don) C.J. Saldanha Inhibits Lung Cancer Growth and Induces Apoptosis via p53/mTOR Signaling Pathway.
Raja K; Vignesh A; Lavanya P; Ravi M; Selvakumar S; Vasanth K
Appl Biochem Biotechnol; 2023 Dec; 195(12):7277-7297. PubMed ID: 36995657
[TBL] [Abstract][Full Text] [Related]
6. Aging and TOR: interwoven in the fabric of life.
Sharp ZD
Cell Mol Life Sci; 2011 Feb; 68(4):587-97. PubMed ID: 20960025
[TBL] [Abstract][Full Text] [Related]
7. Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser.
Gnanapradeepan K; Leu JI; Basu S; Barnoud T; Good M; Lee JV; Quinn WJ; Kung CP; Ahima R; Baur JA; Wellen KE; Liu Q; Schug ZT; George DL; Murphy ME
Elife; 2020 Nov; 9():. PubMed ID: 33170774
[TBL] [Abstract][Full Text] [Related]
8. Evaluation of off-label rapamycin use to promote healthspan in 333 adults.
Kaeberlein TL; Green AS; Haddad G; Hudson J; Isman A; Nyquist A; Rosen BS; Suh Y; Zalzala S; Zhang X; Blagosklonny MV; An JY; Kaeberlein M
Geroscience; 2023 Oct; 45(5):2757-2768. PubMed ID: 37191826
[TBL] [Abstract][Full Text] [Related]
9. Rapamycin and ageing: when, for how long, and how much?
Kaeberlein M
J Genet Genomics; 2014 Sep; 41(9):459-63. PubMed ID: 25269671
[TBL] [Abstract][Full Text] [Related]
10. Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency.
Donehower LA
Aging (Albany NY); 2012 Oct; 4(10):660-1. PubMed ID: 23128359
[TBL] [Abstract][Full Text] [Related]
11. Actinomycin D and nutlin-3a synergistically promote phosphorylation of p53 on serine 46 in cancer cell lines of different origin.
Zajkowicz A; Gdowicz-Kłosok A; Krześniak M; Ścieglińska D; Rusin M
Cell Signal; 2015 Sep; 27(9):1677-87. PubMed ID: 25989210
[TBL] [Abstract][Full Text] [Related]
12. Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome.
Sawada D; Kato H; Kaneko H; Kinoshita D; Funayama S; Minamizuka T; Takasaki A; Igarashi K; Koshizaka M; Takada-Watanabe A; Nakamura R; Aono K; Yamaguchi A; Teramoto N; Maeda Y; Ohno T; Hayashi A; Ide K; Ide S; Shoji M; Kitamoto T; Endo Y; Ogata H; Kubota Y; Mitsukawa N; Iwama A; Ouchi Y; Takayama N; Eto K; Fujii K; Takatani T; Shiohama T; Hamada H; Maezawa Y; Yokote K
Aging (Albany NY); 2023 Oct; 15(19):9948-9964. PubMed ID: 37793000
[TBL] [Abstract][Full Text] [Related]
13. Poly(C)-binding Protein 2 Regulates the p53 Expression via Interactions with the 5'-Terminal Region of p53 mRNA.
Janecki DM; Swiatkowska A; Szpotkowska J; Urbanowicz A; Kabacińska M; Szpotkowski K; Ciesiołka J
Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948101
[TBL] [Abstract][Full Text] [Related]
14. Transcriptome Analysis of Cells Exposed to Actinomycin D and Nutlin-3a Reveals New Candidate p53-Target Genes and Indicates That CHIR-98014 Is an Important Inhibitor of p53 Activity.
Łasut-Szyszka B; Małachowska B; Gdowicz-Kłosok A; Krześniak M; Głowala-Kosińska M; Zajkowicz A; Rusin M
Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681730
[TBL] [Abstract][Full Text] [Related]
15. Characterization of mTOR Activity and Metabolic Profile in Pediatric Rhabdomyosarcoma.
Felkai L; Krencz I; Kiss DJ; Nagy N; Petővári G; Dankó T; Micsík T; Khoor A; Tornóczky T; Sápi Z; Sebestyén A; Csóka M
Cancers (Basel); 2020 Jul; 12(7):. PubMed ID: 32709151
[TBL] [Abstract][Full Text] [Related]
16. Synergistic activation of p53 by actinomycin D and nutlin-3a is associated with the upregulation of crucial regulators and effectors of innate immunity.
Krześniak M; Zajkowicz A; Gdowicz-Kłosok A; Głowala-Kosińska M; Łasut-Szyszka B; Rusin M
Cell Signal; 2020 May; 69():109552. PubMed ID: 32032660
[TBL] [Abstract][Full Text] [Related]
17. Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?
Li F; Aljahdali I; Ling X
J Exp Clin Cancer Res; 2019 Aug; 38(1):368. PubMed ID: 31439015
[TBL] [Abstract][Full Text] [Related]
18. Rapamycin improves sevoflurane‑induced cognitive dysfunction in aged rats by mediating autophagy through the TLR4/MyD88/NF‑κB signaling pathway.
Li Y; Liu L; Tian Y; Zhang J
Mol Med Rep; 2019 Oct; 20(4):3085-3094. PubMed ID: 31432123
[TBL] [Abstract][Full Text] [Related]
19. Rapamycin rescues BMP mediated midline craniosynostosis phenotype through reduction of mTOR signaling in a mouse model.
Kramer K; Yang J; Swanson WB; Hayano S; Toda M; Pan H; Kim JK; Krebsbach PH; Mishina Y
Genesis; 2018 Jun; 56(6-7):e23220. PubMed ID: 30134066
[TBL] [Abstract][Full Text] [Related]
20. Rapamycin Does Not Impede Survival or Induction of Antibody Responses to Primary and Heterosubtypic Influenza Infections in Mice.
Liepkalns JS; Pandey A; Hofstetter AR; Kumar A; Jones EN; Cao W; Liu F; Levine MZ; Sambhara S; Gangappa S
Viral Immunol; 2016 Oct; 29(8):487-493. PubMed ID: 27447349
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]