BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 24917523)

  • 1. Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.
    Smagris E; BasuRay S; Li J; Huang Y; Lai KM; Gromada J; Cohen JC; Hobbs HH
    Hepatology; 2015 Jan; 61(1):108-18. PubMed ID: 24917523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis.
    BasuRay S; Wang Y; Smagris E; Cohen JC; Hobbs HH
    Proc Natl Acad Sci U S A; 2019 May; 116(19):9521-9526. PubMed ID: 31019090
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.
    Lindén D; Ahnmark A; Pingitore P; Ciociola E; Ahlstedt I; Andréasson AC; Sasidharan K; Madeyski-Bengtson K; Zurek M; Mancina RM; Lindblom A; Bjursell M; Böttcher G; Ståhlman M; Bohlooly-Y M; Haynes WG; Carlsson B; Graham M; Lee R; Murray S; Valenti L; Bhanot S; Åkerblad P; Romeo S
    Mol Metab; 2019 Apr; 22():49-61. PubMed ID: 30772256
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage.
    Donati B; Motta BM; Pingitore P; Meroni M; Pietrelli A; Alisi A; Petta S; Xing C; Dongiovanni P; del Menico B; Rametta R; Mancina RM; Badiali S; Fracanzani AL; Craxì A; Fargion S; Nobili V; Romeo S; Valenti L
    Hepatology; 2016 Mar; 63(3):787-98. PubMed ID: 26605757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.
    BasuRay S; Smagris E; Cohen JC; Hobbs HH
    Hepatology; 2017 Oct; 66(4):1111-1124. PubMed ID: 28520213
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro.
    Pirazzi C; Adiels M; Burza MA; Mancina RM; Levin M; Ståhlman M; Taskinen MR; Orho-Melander M; Perman J; Pujia A; Andersson L; Maglio C; Montalcini T; Wiklund O; Borén J; Romeo S
    J Hepatol; 2012 Dec; 57(6):1276-82. PubMed ID: 22878467
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans.
    Ericson E; Bergenholm L; Andréasson AC; Dix CI; Knöchel J; Hansson SF; Lee R; Schumi J; Antonsson M; Fjellström O; Nasr P; Liljeblad M; Carlsson B; Kechagias S; Lindén D; Ekstedt M
    Hepatol Commun; 2022 Oct; 6(10):2689-2701. PubMed ID: 35833455
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis.
    Li JZ; Huang Y; Karaman R; Ivanova PT; Brown HA; Roddy T; Castro-Perez J; Cohen JC; Hobbs HH
    J Clin Invest; 2012 Nov; 122(11):4130-44. PubMed ID: 23023705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Patatin-like phospholipase domain–containing protein 3 promotes transfer of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets.
    Mitsche MA; Hobbs HH; Cohen JC
    J Biol Chem; 2018 May; 293(18):6958-6968. PubMed ID: 29555681
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatic steatosis and PNPLA3 I148M variant are associated with serum Fetuin-A independently of insulin resistance.
    Rametta R; Ruscica M; Dongiovanni P; Macchi C; Fracanzani AL; Steffani L; Fargion S; Magni P; Valenti L
    Eur J Clin Invest; 2014 Jul; 44(7):627-33. PubMed ID: 24828988
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dissociation of Fatty Liver and Insulin Resistance in I148M PNPLA3 Carriers: Differences in Diacylglycerol (DAG) FA18:1 Lipid Species as a Possible Explanation.
    Franko A; Merkel D; Kovarova M; Hoene M; Jaghutriz BA; Heni M; Königsrainer A; Papan C; Lehr S; Häring HU; Peter A
    Nutrients; 2018 Sep; 10(9):. PubMed ID: 30227635
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PNPLA3 I148M Variant Influences Circulating Retinol in Adults with Nonalcoholic Fatty Liver Disease or Obesity.
    Mondul A; Mancina RM; Merlo A; Dongiovanni P; Rametta R; Montalcini T; Valenti L; Albanes D; Romeo S
    J Nutr; 2015 Aug; 145(8):1687-91. PubMed ID: 26136587
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats.
    Kumashiro N; Yoshimura T; Cantley JL; Majumdar SK; Guebre-Egziabher F; Kursawe R; Vatner DF; Fat I; Kahn M; Erion DM; Zhang XM; Zhang D; Manchem VP; Bhanot S; Gerhard GS; Petersen KF; Cline GW; Samuel VT; Shulman GI
    Hepatology; 2013 May; 57(5):1763-72. PubMed ID: 23175050
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PNPLA3 p.I148M variant is associated with greater reduction of liver fat content after bariatric surgery.
    Krawczyk M; Jiménez-Agüero R; Alustiza JM; Emparanza JI; Perugorria MJ; Bujanda L; Lammert F; Banales JM
    Surg Obes Relat Dis; 2016 Dec; 12(10):1838-1846. PubMed ID: 27576208
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant.
    Mancina RM; Matikainen N; Maglio C; Söderlund S; Lundbom N; Hakkarainen A; Rametta R; Mozzi E; Fargion S; Valenti L; Romeo S; Taskinen MR; Borén J
    J Clin Endocrinol Metab; 2015 May; 100(5):E821-5. PubMed ID: 25763607
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Genetic Variant I148M in PNPLA3 Is Associated With Increased Hepatic Retinyl-Palmitate Storage in Humans.
    Kovarova M; Königsrainer I; Königsrainer A; Machicao F; Häring HU; Schleicher E; Peter A
    J Clin Endocrinol Metab; 2015 Dec; 100(12):E1568-74. PubMed ID: 26439088
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis.
    Valenti L; Maggioni P; Piperno A; Rametta R; Pelucchi S; Mariani R; Dongiovanni P; Fracanzani AL; Fargion S
    World J Gastroenterol; 2012 Jun; 18(22):2813-20. PubMed ID: 22719190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Four-Week Omega-3 Supplementation in Carriers of the Prosteatotic PNPLA3 p.I148M Genetic Variant: An Open-Label Study.
    Kuttner CS; Mancina R; Wagenpfeil G; Lammert F; Stokes CS
    Lifestyle Genom; 2019; 12(1-6):10-17. PubMed ID: 31454802
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells.
    Hao L; Ito K; Huang KH; Sae-tan S; Lambert JD; Ross AC
    Metabolism; 2014 Oct; 63(10):1352-62. PubMed ID: 25060692
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease.
    Chen W; Chang B; Li L; Chan L
    Hepatology; 2010 Sep; 52(3):1134-42. PubMed ID: 20648554
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.