These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

371 related articles for article (PubMed ID: 24920999)

  • 1. Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1.
    Sun XX; Dai MS
    World J Biol Chem; 2014 May; 5(2):75-84. PubMed ID: 24920999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein.
    Li Y; Sun XX; Elferich J; Shinde U; David LL; Dai MS
    J Biol Chem; 2014 Feb; 289(8):5097-108. PubMed ID: 24403071
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria.
    Chen Y; Wang YG; Li Y; Sun XX; Dai MS
    Oncotarget; 2017 Feb; 8(7):11053-11062. PubMed ID: 28035068
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1.
    Sun XX; Challagundla KB; Dai MS
    EMBO J; 2012 Feb; 31(3):576-92. PubMed ID: 22124327
    [TBL] [Abstract][Full Text] [Related]  

  • 5. OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination.
    Pasupala N; Morrow ME; Que LT; Malynn BA; Ma A; Wolberger C
    J Biol Chem; 2018 Nov; 293(47):18285-18295. PubMed ID: 30282802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mechanism of OTUB1-mediated inhibition of ubiquitination.
    Wiener R; Zhang X; Wang T; Wolberger C
    Nature; 2012 Feb; 483(7391):618-22. PubMed ID: 22367539
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Otubain 1: a non-canonical deubiquitinase with an emerging role in cancer.
    Saldana M; VanderVorst K; Berg AL; Lee H; Carraway KL
    Endocr Relat Cancer; 2019 Jan; 26(1):R1-R14. PubMed ID: 30400005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.
    Nakada S; Tai I; Panier S; Al-Hakim A; Iemura S; Juang YC; O'Donnell L; Kumakubo A; Munro M; Sicheri F; Gingras AC; Natsume T; Suda T; Durocher D
    Nature; 2010 Aug; 466(7309):941-6. PubMed ID: 20725033
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13.
    Sato Y; Yamagata A; Goto-Ito S; Kubota K; Miyamoto R; Nakada S; Fukai S
    J Biol Chem; 2012 Jul; 287(31):25860-8. PubMed ID: 22679021
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of Cross-Regulation by Different OTUB1:E2 Complexes.
    Que LT; Morrow ME; Wolberger C
    Biochemistry; 2020 Mar; 59(8):921-932. PubMed ID: 32049508
    [TBL] [Abstract][Full Text] [Related]  

  • 11. E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
    Wiener R; DiBello AT; Lombardi PM; Guzzo CM; Zhang X; Matunis MJ; Wolberger C
    Nat Struct Mol Biol; 2013 Sep; 20(9):1033-9. PubMed ID: 23955022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ubiquitin-like modifier FAT10 stimulates the activity of deubiquitylating enzyme OTUB1.
    Bialas J; Boehm AN; Catone N; Aichem A; Groettrup M
    J Biol Chem; 2019 Mar; 294(12):4315-4330. PubMed ID: 30718280
    [TBL] [Abstract][Full Text] [Related]  

  • 13. OTUB1-mediated inhibition of ubiquitination: a growing list of effectors, multiplex mechanisms, and versatile functions.
    Wu M; Sun L; Song T
    Front Mol Biosci; 2023; 10():1261273. PubMed ID: 38264570
    [TBL] [Abstract][Full Text] [Related]  

  • 14. OTUB1 protein suppresses mTOR complex 1 (mTORC1) activity by deubiquitinating the mTORC1 inhibitor DEPTOR.
    Zhao L; Wang X; Yu Y; Deng L; Chen L; Peng X; Jiao C; Gao G; Tan X; Pan W; Ge X; Wang P
    J Biol Chem; 2018 Mar; 293(13):4883-4892. PubMed ID: 29382726
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53 stability is regulated by diverse deubiquitinating enzymes.
    Kwon SK; Saindane M; Baek KH
    Biochim Biophys Acta Rev Cancer; 2017 Dec; 1868(2):404-411. PubMed ID: 28801249
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SET7 methylates the deubiquitinase OTUB1 at Lys
    Deng H; Jia S; Tang J; Rong F; Xu C; Chen X; Wang Z; Zhu C; Sun X; Liao Q; Liu W; Li W; Xiao W; Liu X
    J Biol Chem; 2023 Apr; 299(4):103054. PubMed ID: 36822329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting USP7-Mediated Deubiquitination of MDM2/MDMX-p53 Pathway for Cancer Therapy: Are We There Yet?
    Qi SM; Cheng G; Cheng XD; Xu Z; Xu B; Zhang WD; Qin JJ
    Front Cell Dev Biol; 2020; 8():233. PubMed ID: 32300595
    [TBL] [Abstract][Full Text] [Related]  

  • 18. OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6.
    Zhao Y; Ruan J; Li Z; Su X; Chen K; Lin Y; Cai Y; Wang P; Liu B; Schlüter D; Liang G; Wang X
    Clin Transl Med; 2023 Aug; 13(8):e1385. PubMed ID: 37608493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Target deubiquitinase OTUB1 as a therapeatic strategy for BLCA via β-catenin/necroptosis signal pathway.
    Liao Y; Liang J; Wang Y; Li A; Liu W; Zhong B; Wang K; Zhou D; Guo T; Guo J; Yu X; Jiang N
    Int J Biol Sci; 2024; 20(10):3784-3801. PubMed ID: 39113709
    [TBL] [Abstract][Full Text] [Related]  

  • 20. OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.
    Juang YC; Landry MC; Sanches M; Vittal V; Leung CC; Ceccarelli DF; Mateo AR; Pruneda JN; Mao DY; Szilard RK; Orlicky S; Munro M; Brzovic PS; Klevit RE; Sicheri F; Durocher D
    Mol Cell; 2012 Feb; 45(3):384-97. PubMed ID: 22325355
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.