202 related articles for article (PubMed ID: 24922587)
1. Discovery and structure-activity relationship of novel 2,3-dihydrobenzofuran-7-carboxamide and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide derivatives as poly(ADP-ribose)polymerase-1 inhibitors.
Patel MR; Bhatt A; Steffen JD; Chergui A; Murai J; Pommier Y; Pascal JM; Trombetta LD; Fronczek FR; Talele TT
J Med Chem; 2014 Jul; 57(13):5579-601. PubMed ID: 24922587
[TBL] [Abstract][Full Text] [Related]
2. Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity.
Velagapudi UK; Langelier MF; Delgado-Martin C; Diolaiti ME; Bakker S; Ashworth A; Patel BA; Shao X; Pascal JM; Talele TT
J Med Chem; 2019 Jun; 62(11):5330-5357. PubMed ID: 31042381
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of substituted 2-phenyl-2H-indazole-7-carboxamides as potent poly(ADP-ribose) polymerase (PARP) inhibitors.
Scarpelli R; Boueres JK; Cerretani M; Ferrigno F; Ontoria JM; Rowley M; Schultz-Fademrecht C; Toniatti C; Jones P
Bioorg Med Chem Lett; 2010 Jan; 20(2):488-92. PubMed ID: 20007017
[TBL] [Abstract][Full Text] [Related]
4. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. 2. Structure-activity relationships of novel N-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)amides.
Kataoka K; Shiota T; Takeyasu T; Minoshima T; Watanabe K; Tanaka H; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
J Med Chem; 1996 Mar; 39(6):1262-70. PubMed ID: 8632433
[TBL] [Abstract][Full Text] [Related]
5. Discovery of 2-substituted 1H-benzo[d]immidazole-4-carboxamide derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors with in vivo anti-tumor activity.
Zhou J; Ji M; Zhu Z; Cao R; Chen X; Xu B
Eur J Med Chem; 2017 May; 132():26-41. PubMed ID: 28340412
[TBL] [Abstract][Full Text] [Related]
6. Discovery and SAR study of 2-(1-propylpiperidin-4-yl)-3H-imidazo[4,5-c]pyridine-7-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) for the treatment of cancer.
Zhu Q; Wang X; Hu Y; He X; Gong G; Xu Y
Bioorg Med Chem; 2015 Oct; 23(20):6551-9. PubMed ID: 26422786
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of 2-(4-[4-acetylpiperazine-1-carbonyl] phenyl)-1H-benzo[d]imidazole-4-carboxamide derivatives as potential PARP-1 inhibitors and preliminary study on structure-activity relationship.
Chen M; Huang H; Wu K; Liu Y; Jiang L; Li Y; Tang G; Peng J; Cao X
Drug Dev Res; 2022 Feb; 83(1):55-63. PubMed ID: 34151456
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of novel 5-fluoro-1H-benzimidazole-4-carboxamide derivatives as potent PARP-1 inhibitors.
Wang J; Wang X; Li H; Ji D; Li Y; Xu Y; Zhu Q
Bioorg Med Chem Lett; 2016 Aug; 26(16):4127-32. PubMed ID: 27353531
[TBL] [Abstract][Full Text] [Related]
9. Discovery of 2-(1-(3-(4-Chloroxyphenyl)-3-oxo- propyl)pyrrolidine-3-yl)-1
Min R; Wu W; Wang M; Tang L; Chen D; Zhao H; Zhang C; Jiang Y
Molecules; 2019 May; 24(10):. PubMed ID: 31108884
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors.
Shao X; Pak S; Velagapudi UK; Gobbooru S; Kommaraju SS; Low WK; Subramaniam G; Pathak SK; Talele TT
Bioorg Chem; 2020 Sep; 102():104075. PubMed ID: 32777641
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and evaluation of 1H-benzo[d]imidazole-4-carboxamide PARP-1 inhibitors using different saturated nitrogen-contained heterocycle as linker group.
Wu K; Peng X; Li Y; Chen M; Liu Y; Liu D; Jiang L; He Y; Peng J; Cao X
Chem Biol Drug Des; 2023 Jun; 101(6):1335-1347. PubMed ID: 36752693
[TBL] [Abstract][Full Text] [Related]
12. Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.
White AW; Curtin NJ; Eastman BW; Golding BT; Hostomsky Z; Kyle S; Li J; Maegley KA; Skalitzky DJ; Webber SE; Yu XH; Griffin RJ
Bioorg Med Chem Lett; 2004 May; 14(10):2433-7. PubMed ID: 15109627
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, [¹⁸F] radiolabeling, and evaluation of poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors for in vivo imaging of PARP-1 using positron emission tomography.
Zhou D; Chu W; Xu J; Jones LA; Peng X; Li S; Chen DL; Mach RH
Bioorg Med Chem; 2014 Mar; 22(5):1700-7. PubMed ID: 24503274
[TBL] [Abstract][Full Text] [Related]
14. Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase.
Cockcroft XL; Dillon KJ; Dixon L; Drzewiecki J; Kerrigan F; Loh VM; Martin NM; Menear KA; Smith GC
Bioorg Med Chem Lett; 2006 Feb; 16(4):1040-4. PubMed ID: 16290932
[TBL] [Abstract][Full Text] [Related]
15. Discovery of 1-substituted benzyl-quinazoline-2,4(1H,3H)-dione derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors.
Yao H; Ji M; Zhu Z; Zhou J; Cao R; Chen X; Xu B
Bioorg Med Chem; 2015 Feb; 23(4):681-93. PubMed ID: 25614115
[TBL] [Abstract][Full Text] [Related]
16. Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase.
White AW; Almassy R; Calvert AH; Curtin NJ; Griffin RJ; Hostomsky Z; Maegley K; Newell DR; Srinivasan S; Golding BT
J Med Chem; 2000 Nov; 43(22):4084-97. PubMed ID: 11063605
[TBL] [Abstract][Full Text] [Related]
17. Molecular modeling studies on benzimidazole carboxamide derivatives as PARP-1 inhibitors using 3D-QSAR and docking.
Zeng H; Zhang H; Jang F; Zhao L; Zhang J
Chem Biol Drug Des; 2011 Sep; 78(3):333-52. PubMed ID: 21585709
[TBL] [Abstract][Full Text] [Related]
18. Influence of usnic acid and its derivatives on the activity of mammalian poly(ADP-ribose)polymerase 1 and DNA polymerase β.
Zakharenko A; Sokolov D; Luzina O; Sukhanova M; Khodyreva S; Zakharova O; Salakhutdinov N; Lavrik O
Med Chem; 2012 Sep; 8(5):883-93. PubMed ID: 22741606
[TBL] [Abstract][Full Text] [Related]
19. Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.
Jones P; Altamura S; Boueres J; Ferrigno F; Fonsi M; Giomini C; Lamartina S; Monteagudo E; Ontoria JM; Orsale MV; Palumbi MC; Pesci S; Roscilli G; Scarpelli R; Schultz-Fademrecht C; Toniatti C; Rowley M
J Med Chem; 2009 Nov; 52(22):7170-85. PubMed ID: 19873981
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of tricyclic derivatives containing a non-aromatic amide as inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
Park CH; Chun K; Joe BY; Park JS; Kim YC; Choi JS; Ryu DK; Koh SH; Cho GW; Kim SH; Kim MH
Bioorg Med Chem Lett; 2010 Apr; 20(7):2250-3. PubMed ID: 20189385
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]