314 related articles for article (PubMed ID: 24928508)
1. Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).
Cao J; Meng S; Chang E; Beckwith-Fickas K; Xiong L; Cole RN; Radovick S; Wondisford FE; He L
J Biol Chem; 2014 Jul; 289(30):20435-46. PubMed ID: 24928508
[TBL] [Abstract][Full Text] [Related]
2. Activation of the cAMP-PKA pathway Antagonizes Metformin Suppression of Hepatic Glucose Production.
He L; Chang E; Peng J; An H; McMillin SM; Radovick S; Stratakis CA; Wondisford FE
J Biol Chem; 2016 May; 291(20):10562-70. PubMed ID: 27002150
[TBL] [Abstract][Full Text] [Related]
3. Metformin activates AMP-activated protein kinase by promoting formation of the αβγ heterotrimeric complex.
Meng S; Cao J; He Q; Xiong L; Chang E; Radovick S; Wondisford FE; He L
J Biol Chem; 2015 Feb; 290(6):3793-802. PubMed ID: 25538235
[TBL] [Abstract][Full Text] [Related]
4. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Foretz M; Hébrard S; Leclerc J; Zarrinpashneh E; Soty M; Mithieux G; Sakamoto K; Andreelli F; Viollet B
J Clin Invest; 2010 Jul; 120(7):2355-69. PubMed ID: 20577053
[TBL] [Abstract][Full Text] [Related]
5. Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP.
Kim YD; Park KG; Lee YS; Park YY; Kim DK; Nedumaran B; Jang WG; Cho WJ; Ha J; Lee IK; Lee CH; Choi HS
Diabetes; 2008 Feb; 57(2):306-14. PubMed ID: 17909097
[TBL] [Abstract][Full Text] [Related]
6. AMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner.
Lee JM; Seo WY; Song KH; Chanda D; Kim YD; Kim DK; Lee MW; Ryu D; Kim YH; Noh JR; Lee CH; Chiang JY; Koo SH; Choi HS
J Biol Chem; 2010 Oct; 285(42):32182-91. PubMed ID: 20688914
[TBL] [Abstract][Full Text] [Related]
7. Differential AMPK phosphorylation by glucagon and metformin regulates insulin signaling in human hepatic cells.
Aw DK; Sinha RA; Xie SY; Yen PM
Biochem Biophys Res Commun; 2014 May; 447(4):569-73. PubMed ID: 24735537
[TBL] [Abstract][Full Text] [Related]
8. Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice.
Fujita Y; Hosokawa M; Fujimoto S; Mukai E; Abudukadier A; Obara A; Ogura M; Nakamura Y; Toyoda K; Nagashima K; Seino Y; Inagaki N
Diabetologia; 2010 Jul; 53(7):1472-81. PubMed ID: 20349346
[TBL] [Abstract][Full Text] [Related]
9. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.
Miller RA; Chu Q; Xie J; Foretz M; Viollet B; Birnbaum MJ
Nature; 2013 Feb; 494(7436):256-60. PubMed ID: 23292513
[TBL] [Abstract][Full Text] [Related]
10. Metformin suppresses expression of the selenoprotein P gene via an AMP-activated kinase (AMPK)/FoxO3a pathway in H4IIEC3 hepatocytes.
Takayama H; Misu H; Iwama H; Chikamoto K; Saito Y; Murao K; Teraguchi A; Lan F; Kikuchi A; Saito R; Tajima N; Shirasaki T; Matsugo S; Miyamoto K; Kaneko S; Takamura T
J Biol Chem; 2014 Jan; 289(1):335-45. PubMed ID: 24257750
[TBL] [Abstract][Full Text] [Related]
11. PPP1R3C mediates metformin-inhibited hepatic gluconeogenesis.
Ji X; Wang S; Tang H; Zhang Y; Zhou F; Zhang L; Zhu Q; Zhu K; Liu Q; Liu Y; Wang X; Zhou L
Metabolism; 2019 Sep; 98():62-75. PubMed ID: 31181215
[TBL] [Abstract][Full Text] [Related]
12. Metformin action in human hepatocytes: coactivation of atypical protein kinase C alters 5'-AMP-activated protein kinase effects on lipogenic and gluconeogenic enzyme expression.
Sajan MP; Ivey RA; Farese RV
Diabetologia; 2013 Nov; 56(11):2507-16. PubMed ID: 23933835
[TBL] [Abstract][Full Text] [Related]
13. Entada phaseoloides extract suppresses hepatic gluconeogenesis via activation of the AMPK signaling pathway.
Zheng T; Hao X; Wang Q; Chen L; Jin S; Bian F
J Ethnopharmacol; 2016 Dec; 193():691-699. PubMed ID: 27742409
[TBL] [Abstract][Full Text] [Related]
14. The importance of the AMPK gamma 1 subunit in metformin suppression of liver glucose production.
An H; Wang Y; Qin C; Li M; Maheshwari A; He L
Sci Rep; 2020 Jun; 10(1):10482. PubMed ID: 32591547
[TBL] [Abstract][Full Text] [Related]
15. Bidirectional regulation of adenosine 5'-monophosphate-activated protein kinase activity by berberine and metformin in response to changes in ambient glucose concentration.
Xiao Y; Xu M; Alimujiang M; Bao Y; Wei L; Yin J
J Cell Biochem; 2018 Dec; 119(12):9910-9920. PubMed ID: 30129983
[TBL] [Abstract][Full Text] [Related]
16. Molecular action of metformin in hepatocytes: an updated insight.
Sliwinska A; Drzewoski J
Curr Diabetes Rev; 2015; 11(3):175-81. PubMed ID: 25808533
[TBL] [Abstract][Full Text] [Related]
17. Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status.
Stephenne X; Foretz M; Taleux N; van der Zon GC; Sokal E; Hue L; Viollet B; Guigas B
Diabetologia; 2011 Dec; 54(12):3101-10. PubMed ID: 21947382
[TBL] [Abstract][Full Text] [Related]
18. Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats.
Jiang SJ; Dong H; Li JB; Xu LJ; Zou X; Wang KF; Lu FE; Yi P
World J Gastroenterol; 2015 Jul; 21(25):7777-85. PubMed ID: 26167077
[TBL] [Abstract][Full Text] [Related]
19. Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2).
Madsen A; Bozickovic O; Bjune JI; Mellgren G; Sagen JV
Sci Rep; 2015 Nov; 5():16430. PubMed ID: 26548416
[TBL] [Abstract][Full Text] [Related]
20. An active part of Artemisia sacrorum Ledeb. suppresses gluconeogenesis through AMPK mediated GSK3β and CREB phosphorylation in human HepG2 cells.
Yuan HD; Piao GC
Biosci Biotechnol Biochem; 2011; 75(6):1079-84. PubMed ID: 21670525
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]