BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 24928612)

  • 21. Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers.
    Nobori T; Takabayashi K; Tran P; Orvis L; Batova A; Yu AL; Carson DA
    Proc Natl Acad Sci U S A; 1996 Jun; 93(12):6203-8. PubMed ID: 8650244
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Homozygous deletions of methylthioadenosine phosphorylase (MTAP) are more frequent than p16INK4A (CDKN2) homozygous deletions in primary non-small cell lung cancers (NSCLC).
    Schmid M; Malicki D; Nobori T; Rosenbach MD; Campbell K; Carson DA; Carrera CJ
    Oncogene; 1998 Nov; 17(20):2669-75. PubMed ID: 9840931
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells.
    Hori H; Tran P; Carrera CJ; Hori Y; Rosenbach MD; Carson DA; Nobori T
    Cancer Res; 1996 Dec; 56(24):5653-8. PubMed ID: 8971171
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Codeletion of the genes for p16INK4, methylthioadenosine phosphorylase, interferon-alpha1, interferon-beta1, and other 9p21 markers in human malignant cell lines.
    Zhang H; Chen ZH; Savarese TM
    Cancer Genet Cytogenet; 1996 Jan; 86(1):22-8. PubMed ID: 8616780
    [TBL] [Abstract][Full Text] [Related]  

  • 25. EFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine.
    Batova A; Cottam H; Yu J; Diccianni MB; Carrera CJ; Yu AL
    Blood; 2006 Feb; 107(3):898-903. PubMed ID: 16234352
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).
    Kirovski G; Stevens AP; Czech B; Dettmer K; Weiss TS; Wild P; Hartmann A; Bosserhoff AK; Oefner PJ; Hellerbrand C
    Am J Pathol; 2011 Mar; 178(3):1145-52. PubMed ID: 21356366
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer.
    Subhi AL; Tang B; Balsara BR; Altomare DA; Testa JR; Cooper HS; Hoffman JP; Meropol NJ; Kruger WD
    Clin Cancer Res; 2004 Nov; 10(21):7290-6. PubMed ID: 15534104
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Methylthioadenosine phosphorylase deficiency in Japanese osteosarcoma patients.
    Miyazaki S; Nishioka J; Shiraishi T; Matsumine A; Uchida A; Nobori T
    Int J Oncol; 2007 Nov; 31(5):1069-76. PubMed ID: 17912432
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Downregulation of methylthioadenosin phosphorylase by homozygous deletion in gastric carcinoma.
    Kim J; Kim MA; Min SY; Jee CD; Lee HE; Kim WH
    Genes Chromosomes Cancer; 2011 Jun; 50(6):421-33. PubMed ID: 21412930
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.
    Basu I; Locker J; Cassera MB; Belbin TJ; Merino EF; Dong X; Hemeon I; Evans GB; Guha C; Schramm VL
    J Biol Chem; 2011 Feb; 286(6):4902-11. PubMed ID: 21135097
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL).
    Harasawa H; Yamada Y; Kudoh M; Sugahara K; Soda H; Hirakata Y; Sasaki H; Ikeda S; Matsuo T; Tomonaga M; Nobori T; Kamihira S
    Leukemia; 2002 Sep; 16(9):1799-807. PubMed ID: 12200696
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer.
    Kindler HL; Burris HA; Sandler AB; Oliff IA
    Invest New Drugs; 2009 Feb; 27(1):75-81. PubMed ID: 18618081
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Fine-mapping loss of gene architecture at the CDKN2B (p15INK4b), CDKN2A (p14ARF, p16INK4a), and MTAP genes in head and neck squamous cell carcinoma.
    Worsham MJ; Chen KM; Tiwari N; Pals G; Schouten JP; Sethi S; Benninger MS
    Arch Otolaryngol Head Neck Surg; 2006 Apr; 132(4):409-15. PubMed ID: 16618910
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Immunohistochemical diagnosis of methylthioadenosine phosphorylase (MTAP) deficiency in non-small cell lung carcinoma.
    Watanabe F; Takao M; Inoue K; Nishioka J; Nobori T; Shiraishi T; Kaneda M; Sakai T; Yada I; Shimpo H
    Lung Cancer; 2009 Jan; 63(1):39-44. PubMed ID: 18555557
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Early Clinical Success of MTA-Cooperative PRMT5 Inhibitors for the Treatment of CDKN2A/MTAP-Deleted Cancers.
    Mulvaney KM
    Cancer Discov; 2023 Nov; 13(11):2310-2312. PubMed ID: 37909092
    [TBL] [Abstract][Full Text] [Related]  

  • 36. MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis.
    Marjon K; Cameron MJ; Quang P; Clasquin MF; Mandley E; Kunii K; McVay M; Choe S; Kernytsky A; Gross S; Konteatis Z; Murtie J; Blake ML; Travins J; Dorsch M; Biller SA; Marks KM
    Cell Rep; 2016 Apr; 15(3):574-587. PubMed ID: 27068473
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Status of methylthioadenosine phosphorylase and its impact on cellular response to L-alanosine and methylmercaptopurine riboside in human soft tissue sarcoma cells.
    Li W; Su D; Mizobuchi H; Martin DS; Gu B; Gorlick R; Cole P; Bertino JR
    Oncol Res; 2004; 14(7-8):373-9. PubMed ID: 15301428
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis of purines in human lymphoblast cells deficient in methylthioadenosine phosphorylase activity.
    Gordon RB; Blackwell K; Emmerson BT
    Biochim Biophys Acta; 1987 Jan; 927(1):1-7. PubMed ID: 3098299
    [TBL] [Abstract][Full Text] [Related]  

  • 39. MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.
    Kryukov GV; Wilson FH; Ruth JR; Paulk J; Tsherniak A; Marlow SE; Vazquez F; Weir BA; Fitzgerald ME; Tanaka M; Bielski CM; Scott JM; Dennis C; Cowley GS; Boehm JS; Root DE; Golub TR; Clish CB; Bradner JE; Hahn WC; Garraway LA
    Science; 2016 Mar; 351(6278):1214-8. PubMed ID: 26912360
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Detection of methylthioadenosine phosphorylase (MTAP) and p16 gene deletion in T cell acute lymphoblastic leukemia by real-time quantitative PCR assay.
    M'soka TJ; Nishioka J; Taga A; Kato K; Kawasaki H; Yamada Y; Yu A; Komada Y; Nobori T
    Leukemia; 2000 May; 14(5):935-40. PubMed ID: 10803528
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.