BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

679 related articles for article (PubMed ID: 24929293)

  • 1. 7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
    Korabecny J; Dolezal R; Cabelova P; Horova A; Hruba E; Ricny J; Sedlacek L; Nepovimova E; Spilovska K; Andrs M; Musilek K; Opletalova V; Sepsova V; Ripova D; Kuca K
    Eur J Med Chem; 2014 Jul; 82():426-38. PubMed ID: 24929293
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.
    Korabecny J; Musilek K; Holas O; Binder J; Zemek F; Marek J; Pohanka M; Opletalova V; Dohnal V; Kuca K
    Bioorg Med Chem Lett; 2010 Oct; 20(20):6093-5. PubMed ID: 20817518
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease.
    Bautista-Aguilera OM; Esteban G; Bolea I; Nikolic K; Agbaba D; Moraleda I; Iriepa I; Samadi A; Soriano E; Unzeta M; Marco-Contelles J
    Eur J Med Chem; 2014 Mar; 75():82-95. PubMed ID: 24530494
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, kinetic studies and molecular modeling of novel tacrine dimers as cholinesterase inhibitors.
    de Aquino RA; Modolo LV; Alves RB; de Fátima Â
    Org Biomol Chem; 2013 Dec; 11(48):8395-409. PubMed ID: 24186541
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
    Bautista-Aguilera OM; Esteban G; Chioua M; Nikolic K; Agbaba D; Moraleda I; Iriepa I; Soriano E; Samadi A; Unzeta M; Marco-Contelles J
    Drug Des Devel Ther; 2014; 8():1893-910. PubMed ID: 25378907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
    J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
    Camps P; Formosa X; Galdeano C; Gómez T; Muñoz-Torrero D; Scarpellini M; Viayna E; Badia A; Clos MV; Camins A; Pallàs M; Bartolini M; Mancini F; Andrisano V; Estelrich J; Lizondo M; Bidon-Chanal A; Luque FJ
    J Med Chem; 2008 Jun; 51(12):3588-98. PubMed ID: 18517184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Shao D; Zou C; Luo C; Tang X; Li Y
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4639-42. PubMed ID: 15324879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
    Alonso D; Dorronsoro I; Rubio L; Muñoz P; García-Palomero E; Del Monte M; Bidon-Chanal A; Orozco M; Luque FJ; Castro A; Medina M; Martínez A
    Bioorg Med Chem; 2005 Dec; 13(24):6588-97. PubMed ID: 16230018
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological activity of new donepezil-hydrazinonicotinamide hybrids.
    Zurek E; Szymański P; Mikiciuk-Olasik E
    Drug Res (Stuttg); 2013 Mar; 63(3):137-44. PubMed ID: 23447117
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
    Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
    Li F; Wang ZM; Wu JJ; Wang J; Xie SS; Lan JS; Xu W; Kong LY; Wang XB
    J Enzyme Inhib Med Chem; 2016; 31(sup3):41-53. PubMed ID: 27384289
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
    Xie SS; Wang XB; Li JY; Yang L; Kong LY
    Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as potent acetylcholinesterase inhibitors.
    Asadipour A; Alipour M; Jafari M; Khoobi M; Emami S; Nadri H; Sakhteman A; Moradi A; Sheibani V; Homayouni Moghadam F; Shafiee A; Foroumadi A
    Eur J Med Chem; 2013; 70():623-30. PubMed ID: 24211638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of 4-substituted coumarins as novel acetylcholinesterase inhibitors.
    Razavi SF; Khoobi M; Nadri H; Sakhteman A; Moradi A; Emami S; Foroumadi A; Shafiee A
    Eur J Med Chem; 2013 Jun; 64():252-9. PubMed ID: 23644208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
    Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
    Wang J; Wang ZM; Li XM; Li F; Wu JJ; Kong LY; Wang XB
    Bioorg Med Chem; 2016 Sep; 24(18):4324-4338. PubMed ID: 27460699
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
    Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Xie SS; Lan JS; Wang X; Wang ZM; Jiang N; Li F; Wu JJ; Wang J; Kong LY
    Bioorg Med Chem; 2016 Apr; 24(7):1528-39. PubMed ID: 26917219
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease.
    Hamulakova S; Janovec L; Hrabinova M; Kristian P; Kuca K; Banasova M; Imrich J
    Eur J Med Chem; 2012 Sep; 55():23-31. PubMed ID: 22818849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.