BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 24931695)

  • 1. Stabilization of VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives.
    Wu Y; Zan LP; Wang XD; Lu YJ; Ou TM; Lin J; Huang ZS; Gu LQ
    Biochim Biophys Acta; 2014 Sep; 1840(9):2970-7. PubMed ID: 24931695
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives.
    Wang XD; Ou TM; Lu YJ; Li Z; Xu Z; Xi C; Tan JH; Huang SL; An LK; Li D; Gu LQ; Huang ZS
    J Med Chem; 2010 Jun; 53(11):4390-8. PubMed ID: 20481493
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
    Lu YJ; Ou TM; Tan JH; Hou JQ; Shao WY; Peng D; Sun N; Wang XD; Wu WB; Bu XZ; Huang ZS; Ma DL; Wong KY; Gu LQ
    J Med Chem; 2008 Oct; 51(20):6381-92. PubMed ID: 18821749
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.
    Sun D; Guo K; Rusche JJ; Hurley LH
    Nucleic Acids Res; 2005; 33(18):6070-80. PubMed ID: 16239639
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.
    Ou TM; Lu YJ; Zhang C; Huang ZS; Wang XD; Tan JH; Chen Y; Ma DL; Wong KY; Tang JC; Chan AS; Gu LQ
    J Med Chem; 2007 Apr; 50(7):1465-74. PubMed ID: 17346034
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel bisindole-PBD conjugate inhibits angiogenesis by regulating STAT3 and VEGF in breast cancer cells.
    Sarma P; Ramaiah MJ; Pal D; Bhadra U; Pal Bhadra M
    Life Sci; 2016 Apr; 151():264-276. PubMed ID: 26979778
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of Quindoline derivative with telomeric repeat-containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2.
    Zhang Y; Zeng D; Cao J; Wang M; Shu B; Kuang G; Ou TM; Tan JH; Gu LQ; Huang ZS; Li D
    Biochim Biophys Acta Gen Subj; 2017 Dec; 1861(12):3246-3256. PubMed ID: 28943299
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Total alkaloids of Rubus alceifolius Poir shows anti-angiogenic activity in vivo and in vitro.
    Zhao J; Lin W; Zhuang Q; Zhong X; Cao Z; Hong Z; Peng J
    Integr Cancer Ther; 2014 Nov; 13(6):520-8. PubMed ID: 25148840
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.
    Zhou JL; Lu YJ; Ou TM; Zhou JM; Huang ZS; Zhu XF; Du CJ; Bu XZ; Ma L; Gu LQ; Li YM; Chan AS
    J Med Chem; 2005 Nov; 48(23):7315-21. PubMed ID: 16279791
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New Disubstituted Quindoline Derivatives Inhibiting Burkitt's Lymphoma Cell Proliferation by Impeding c-MYC Transcription.
    Liu HY; Chen AC; Yin QK; Li Z; Huang SM; Du G; He JH; Zan LP; Wang SK; Xu YH; Tan JH; Ou TM; Li D; Gu LQ; Huang ZS
    J Med Chem; 2017 Jul; 60(13):5438-5454. PubMed ID: 28603988
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A dihydroindolizino indole derivative selectively stabilizes G-quadruplex DNA and down-regulates c-MYC expression in human cancer cells.
    Nagesh N; Raju G; Srinivas R; Ramesh P; Reddy MD; Reddy ChR
    Biochim Biophys Acta; 2015 Jan; 1850(1):129-40. PubMed ID: 25452213
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of MDM2 inhibitors on vascular endothelial growth factor-mediated tumor angiogenesis in human breast cancer.
    Xiong J; Yang Q; Li J; Zhou S
    Angiogenesis; 2014 Jan; 17(1):37-50. PubMed ID: 23907365
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer.
    Zhang Y; Liu J; Lin J; Zhou L; Song Y; Wei B; Luo X; Chen Z; Chen Y; Xiong J; Xu X; Ding L; Ye Q
    Oncotarget; 2016 Mar; 7(9):9859-75. PubMed ID: 26848522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines.
    Zhou JM; Zhu XF; Lu YJ; Deng R; Huang ZS; Mei YP; Wang Y; Huang WL; Liu ZC; Gu LQ; Zeng YX
    Oncogene; 2006 Jan; 25(4):503-11. PubMed ID: 16170347
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents.
    Sun D; Liu WJ; Guo K; Rusche JJ; Ebbinghaus S; Gokhale V; Hurley LH
    Mol Cancer Ther; 2008 Apr; 7(4):880-9. PubMed ID: 18413801
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, Synthesis, and Evaluation of Novel p-(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex.
    Peng W; Sun ZY; Zhang Q; Cheng SQ; Wang SK; Wang XN; Kuang GT; Su XX; Tan JH; Huang ZS; Ou TM
    J Med Chem; 2018 Aug; 61(15):6629-6646. PubMed ID: 29799749
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anti-angiogenic activity of gecko aqueous extracts and its macromolecular components in CAM and HUVE-12 cells.
    Tang Z; Huang SQ; Liu JT; Jiang GX; Wang CM
    Asian Pac J Cancer Prev; 2015; 16(5):2081-6. PubMed ID: 25773854
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antiangiogenic and antiproliferative effects of substituted-1,3,4-oxadiazole derivatives is mediated by down regulation of VEGF and inhibition of translocation of HIF-1alpha in Ehrlich ascites tumor cells.
    Kumar A; D'Souza SS; Nagaraj SR; Gaonkar SL; Salimath BP; Rai KM
    Cancer Chemother Pharmacol; 2009 Nov; 64(6):1221-33. PubMed ID: 19370348
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IGFBP-2 enhances VEGF gene promoter activity and consequent promotion of angiogenesis by neuroblastoma cells.
    Azar WJ; Azar SH; Higgins S; Hu JF; Hoffman AR; Newgreen DF; Werther GA; Russo VC
    Endocrinology; 2011 Sep; 152(9):3332-42. PubMed ID: 21750048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis.
    Hahm ER; Gho YS; Park S; Park C; Kim KW; Yang CH
    Biochem Biophys Res Commun; 2004 Aug; 321(2):337-44. PubMed ID: 15358181
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.