These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 24934992)

  • 1. Novel pyrazoline derivatives as bi-inhibitor of COX-2 and B-Raf in treating cervical carcinoma.
    Yu M; Yang H; Wu K; Ji Y; Ju L; Lu X
    Bioorg Med Chem; 2014 Aug; 22(15):4109-18. PubMed ID: 24934992
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, modification and 3D QSAR studies of novel 2,3-dihydrobenzo[b][1,4]dioxin-containing 4,5-dihydro-1H-pyrazole derivatives as inhibitors of B-Raf kinase.
    Yang YS; Li QS; Sun S; Zhang YB; Wang XL; Zhang F; Tang JF; Zhu HL
    Bioorg Med Chem; 2012 Oct; 20(20):6048-58. PubMed ID: 22985962
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, biological evaluation and 3D QSAR studies of novel dioxin-containing triaryl pyrazoline derivatives as potential B-Raf inhibitors.
    Yang YS; Yang B; Zou Y; Li G; Zhu HL
    Bioorg Med Chem; 2016 Jul; 24(13):3052-3061. PubMed ID: 27238841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, modification and 3D QSAR studies of novel naphthalin-containing pyrazoline derivatives with/without thiourea skeleton as anticancer agents.
    Yang W; Hu Y; Yang YS; Zhang F; Zhang YB; Wang XL; Tang JF; Zhong WQ; Zhu HL
    Bioorg Med Chem; 2013 Mar; 21(5):1050-63. PubMed ID: 23391364
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of novel 5-phenyl-1H-pyrazole derivatives as potential BRAF(V600E) inhibitors.
    Wang SF; Zhu YL; Zhu PT; Makawana JA; Zhang YL; Zhao MY; Lv PC; Zhu HL
    Bioorg Med Chem; 2014 Nov; 22(21):6201-8. PubMed ID: 25267006
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, biological evaluation and 3D-QSAR studies of novel 4,5-dihydro-1H-pyrazole niacinamide derivatives as BRAF inhibitors.
    Li CY; Li QS; Yan L; Sun XG; Wei R; Gong HB; Zhu HL
    Bioorg Med Chem; 2012 Jun; 20(12):3746-55. PubMed ID: 22583669
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and optimization of pyrazoline compounds as B-Raf inhibitors.
    Duffey MO; Adams R; Blackburn C; Chau RW; Chen S; Galvin KM; Garcia K; Gould AE; Greenspan PD; Harrison S; Huang SC; Kim MS; Kulkarni B; Langston S; Liu JX; Ma LT; Menon S; Nagayoshi M; Rowland RS; Vos TJ; Xu T; Yang JJ; Yu S; Zhang Q
    Bioorg Med Chem Lett; 2010 Aug; 20(16):4800-4. PubMed ID: 20634068
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, biological evaluation of novel 4,5-dihydro-2H-pyrazole 2-hydroxyphenyl derivatives as BRAF inhibitors.
    Liu JJ; Zhang H; Sun J; Wang ZC; Yang YS; Li DD; Zhang F; Gong HB; Zhu HL
    Bioorg Med Chem; 2012 Oct; 20(20):6089-96. PubMed ID: 22985957
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study.
    El-Sayed MA; Abdel-Aziz NI; Abdel-Aziz AA; El-Azab AS; Asiri YA; Eltahir KE
    Bioorg Med Chem; 2011 Jun; 19(11):3416-24. PubMed ID: 21570309
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, biological evaluation and 3D-QSAR study of novel 4,5-dihydro-1H-pyrazole thiazole derivatives as BRAF(V⁶⁰⁰E) inhibitors.
    Zhao MY; Yin Y; Yu XW; Sangani CB; Wang SF; Lu AM; Yang LF; Lv PC; Jiang MG; Zhu HL
    Bioorg Med Chem; 2015 Jan; 23(1):46-54. PubMed ID: 25496804
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of novel pyrazole–thiadiazole hybrid as potential potent and selective cyclooxygenase-2 (COX-2) inhibitors.
    Alegaon SG; Hirpara MB; Alagawadi KR; Hullatti KK; Kashniyal K
    Bioorg Med Chem Lett; 2014 Nov; 24(22):5324-9. PubMed ID: 25444084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2.
    El-Sayed MA; Abdel-Aziz NI; Abdel-Aziz AA; El-Azab AS; ElTahir KE
    Bioorg Med Chem; 2012 May; 20(10):3306-16. PubMed ID: 22516672
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, biological evaluation and molecular modeling of dihydro-pyrazolyl-thiazolinone derivatives as potential COX-2 inhibitors.
    Qiu KM; Yan R; Xing M; Wang HH; Cui HE; Gong HB; Zhu HL
    Bioorg Med Chem; 2012 Nov; 20(22):6648-54. PubMed ID: 23062711
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, biological evaluation and molecular modeling of dihydropyrazole sulfonamide derivatives as potential COX-1/COX-2 inhibitors.
    Chen Z; Wang ZC; Yan XQ; Wang PF; Lu XY; Chen LW; Zhu HL; Zhang HW
    Bioorg Med Chem Lett; 2015 May; 25(9):1947-51. PubMed ID: 25866240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modification, biological evaluation and 3D QSAR studies of novel 2-(1,3-diaryl- 4,5-dihydro-1H-pyrazol-5-yl)phenol derivatives as inhibitors of B-Raf kinase.
    Yang YS; Zhang F; Tang DJ; Yang YH; Zhu HL
    PLoS One; 2014; 9(5):e95702. PubMed ID: 24827980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors.
    Fioravanti R; Bolasco A; Manna F; Rossi F; Orallo F; Ortuso F; Alcaro S; Cirilli R
    Eur J Med Chem; 2010 Dec; 45(12):6135-8. PubMed ID: 20974503
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of pyridine acyl sulfonamide derivatives as novel COX-2 inhibitors.
    Lu X; Zhang H; Li X; Chen G; Li QS; Luo Y; Ruan BF; Chen XW; Zhu HL
    Bioorg Med Chem; 2011 Nov; 19(22):6827-32. PubMed ID: 22000948
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and biological evaluation of novel triaryl pyrazoline derivatives with dioxane moiety for selective BRAF
    Li HL; Su MM; Xu YJ; Xu C; Yang YS; Zhu HL
    Eur J Med Chem; 2018 Jul; 155():725-735. PubMed ID: 29940463
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of a new series of highly potent RAF kinase-inhibiting triarylpyrazole derivatives possessing antiproliferative activity against melanoma cells.
    Khan MA; El-Gamal MI; Tarazi H; Choi HS; Oh CH
    Future Med Chem; 2016 Dec; 8(18):2197-2211. PubMed ID: 27845592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of new water-soluble tetrazolide derivatives of celecoxib and rofecoxib as selective cyclooxygenase-2 (COX-2) inhibitors.
    Navidpour L; Amini M; Shafaroodi H; Abdi K; Ghahremani MH; Dehpour AR; Shafiee A
    Bioorg Med Chem Lett; 2006 Sep; 16(17):4483-7. PubMed ID: 16806914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.