These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
11. Cladosporin Derivatives Obtained by Biotransformation Provide Guidance for the Focused Derivatization of this Antimalarial Lead Compound. Fredenhagen A; Schroer K; Schröder H; Hoepfner D; Ligibel M; Porchet Zemp L; Radoch C; Freund E; Meishammer A Chembiochem; 2019 Mar; 20(5):650-654. PubMed ID: 30347507 [TBL] [Abstract][Full Text] [Related]
12. Structural analyses of the malaria parasite aminoacyl-tRNA synthetases provide new avenues for antimalarial drug discovery. Chhibber-Goel J; Yogavel M; Sharma A Protein Sci; 2021 Sep; 30(9):1793-1803. PubMed ID: 34184352 [TBL] [Abstract][Full Text] [Related]
13. Toolkit of Approaches To Support Target-Focused Drug Discovery for Milne R; Wiedemar N; Corpas-Lopez V; Moynihan E; Wall RJ; Dawson A; Robinson DA; Shepherd SM; Smith RJ; Hallyburton I; Post JM; Dowers K; Torrie LS; Gilbert IH; Baragaña B; Patterson S; Wyllie S ACS Infect Dis; 2022 Sep; 8(9):1962-1974. PubMed ID: 36037410 [TBL] [Abstract][Full Text] [Related]
14. Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor. Fang P; Han H; Wang J; Chen K; Chen X; Guo M Chem Biol; 2015 Jun; 22(6):734-44. PubMed ID: 26074468 [TBL] [Abstract][Full Text] [Related]
15. An all-purpose antimalarial drug target. Guiguemde WA; Guy RK Cell Host Microbe; 2012 Jun; 11(6):555-7. PubMed ID: 22704614 [TBL] [Abstract][Full Text] [Related]
16. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Baragaña B; Forte B; Choi R; Nakazawa Hewitt S; Bueren-Calabuig JA; Pisco JP; Peet C; Dranow DM; Robinson DA; Jansen C; Norcross NR; Vinayak S; Anderson M; Brooks CF; Cooper CA; Damerow S; Delves M; Dowers K; Duffy J; Edwards TE; Hallyburton I; Horst BG; Hulverson MA; Ferguson L; Jiménez-Díaz MB; Jumani RS; Lorimer DD; Love MS; Maher S; Matthews H; McNamara CW; Miller P; O'Neill S; Ojo KK; Osuna-Cabello M; Pinto E; Post J; Riley J; Rottmann M; Sanz LM; Scullion P; Sharma A; Shepherd SM; Shishikura Y; Simeons FRC; Stebbins EE; Stojanovski L; Straschil U; Tamaki FK; Tamjar J; Torrie LS; Vantaux A; Witkowski B; Wittlin S; Yogavel M; Zuccotto F; Angulo-Barturen I; Sinden R; Baum J; Gamo FJ; Mäser P; Kyle DE; Winzeler EA; Myler PJ; Wyatt PG; Floyd D; Matthews D; Sharma A; Striepen B; Huston CD; Gray DW; Fairlamb AH; Pisliakov AV; Walpole C; Read KD; Van Voorhis WC; Gilbert IH Proc Natl Acad Sci U S A; 2019 Apr; 116(14):7015-7020. PubMed ID: 30894487 [TBL] [Abstract][Full Text] [Related]
17. Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent. Cochrane RV; Sanichar R; Lambkin GR; Reiz B; Xu W; Tang Y; Vederas JC Angew Chem Int Ed Engl; 2016 Jan; 55(2):664-8. PubMed ID: 26783060 [TBL] [Abstract][Full Text] [Related]
18. Inhibition of Plasmodium falciparum Lysyl-tRNA synthetase via an anaplastic lymphoma kinase inhibitor. Zhou J; Huang Z; Zheng L; Hei Z; Wang Z; Yu B; Jiang L; Wang J; Fang P Nucleic Acids Res; 2020 Nov; 48(20):11566-11576. PubMed ID: 33053158 [TBL] [Abstract][Full Text] [Related]
19. Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Zhou J; Xia M; Huang Z; Qiao H; Yang G; Qian Y; Li P; Zhang Z; Gao X; Jiang L; Wang J; Li W; Fang P Commun Biol; 2024 Jun; 7(1):742. PubMed ID: 38890421 [TBL] [Abstract][Full Text] [Related]
20. The growing pipeline of natural aminoacyl-tRNA synthetase inhibitors for malaria treatment. Saint-Léger A; Sinadinos C; Ribas de Pouplana L Bioengineered; 2016 Apr; 7(2):60-4. PubMed ID: 26963157 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]