These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 24947438)

  • 1. Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.
    Kashyap SS; Johnson JR; McCue HV; Chen X; Edmonds MJ; Ayala M; Graham ME; Jenn RC; Barclay JW; Burgoyne RD; Morgan A
    Hum Mol Genet; 2014 Nov; 23(22):5916-27. PubMed ID: 24947438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Caenorhabditis elegans model of autosomal dominant adult-onset neuronal ceroid lipofuscinosis identifies ethosuximide as a potential therapeutic.
    Barker E; Morgan A; Barclay JW
    Hum Mol Genet; 2023 May; 32(11):1772-1785. PubMed ID: 36282524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression profile of a Caenorhabditis elegans model of adult neuronal ceroid lipofuscinosis reveals down regulation of ubiquitin E3 ligase components.
    McCue HV; Chen X; Barclay JW; Morgan A; Burgoyne RD
    Sci Rep; 2015 Sep; 5():14392. PubMed ID: 26395859
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation.
    Lee J; Xu Y; Saidi L; Xu M; Zinsmaier K; Ye Y
    Autophagy; 2023 Jan; 19(1):204-223. PubMed ID: 35506243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autosomal-dominant adult neuronal ceroid lipofuscinosis caused by duplication in DNAJC5 initially missed by Sanger and whole-exome sequencing.
    Jedličková I; Cadieux-Dion M; Přistoupilová A; Stránecký V; Hartmannová H; Hodaňová K; Barešová V; Hůlková H; Sikora J; Nosková L; Mušálková D; Vyleťal P; Sovová J; Cossette P; Andermann E; Andermann F; Kmoch S;
    Eur J Hum Genet; 2020 Jun; 28(6):783-789. PubMed ID: 31919451
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tissue distribution of cysteine string protein/DNAJC5 in C. elegans analysed by CRISPR/Cas9-mediated tagging of endogenous DNJ-14.
    Barker E; Morgan A; Barclay JW
    Cell Tissue Res; 2024 Apr; 396(1):41-55. PubMed ID: 38403745
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations in DNAJC5, encoding cysteine-string protein alpha, cause autosomal-dominant adult-onset neuronal ceroid lipofuscinosis.
    Nosková L; Stránecký V; Hartmannová H; Přistoupilová A; Barešová V; Ivánek R; Hůlková H; Jahnová H; van der Zee J; Staropoli JF; Sims KB; Tyynelä J; Van Broeckhoven C; Nijssen PC; Mole SE; Elleder M; Kmoch S
    Am J Hum Genet; 2011 Aug; 89(2):241-52. PubMed ID: 21820099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gene Therapy of Adult Neuronal Ceroid Lipofuscinoses with CRISPR/Cas9 in Zebrafish.
    Yao X; Liu X; Zhang Y; Li Y; Zhao C; Yao S; Wei Y
    Hum Gene Ther; 2017 Jul; 28(7):588-597. PubMed ID: 28478735
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases.
    Muñoz-Lobato F; Rodríguez-Palero MJ; Naranjo-Galindo FJ; Shephard F; Gaffney CJ; Szewczyk NJ; Hamamichi S; Caldwell KA; Caldwell GA; Link CD; Miranda-Vizuete A
    Antioxid Redox Signal; 2014 Jan; 20(2):217-35. PubMed ID: 23641861
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model.
    Takayanagi-Kiya S; Jin Y
    G3 (Bethesda); 2016 Jul; 6(7):2165-71. PubMed ID: 27185401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis.
    Greaves J; Lemonidis K; Gorleku OA; Cruchaga C; Grefen C; Chamberlain LH
    J Biol Chem; 2012 Oct; 287(44):37330-9. PubMed ID: 22902780
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans.
    Bass TM; Weinkove D; Houthoofd K; Gems D; Partridge L
    Mech Ageing Dev; 2007 Oct; 128(10):546-52. PubMed ID: 17875315
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression.
    Chen X; McCue HV; Wong SQ; Kashyap SS; Kraemer BC; Barclay JW; Burgoyne RD; Morgan A
    Mol Neurodegener; 2015 Sep; 10():51. PubMed ID: 26419537
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis.
    Diez-Ardanuy C; Greaves J; Munro KR; Tomkinson NC; Chamberlain LH
    Sci Rep; 2017 Jan; 7(1):10. PubMed ID: 28127059
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss.
    Benitez BA; Cairns NJ; Schmidt RE; Morris JC; Norton JB; Cruchaga C; Sands MS
    Acta Neuropathol Commun; 2015 Nov; 3():73. PubMed ID: 26610600
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuron dysfunction is induced by prion protein with an insertional mutation via a Fyn kinase and reversed by sirtuin activation in Caenorhabditis elegans.
    Bizat N; Peyrin JM; Haïk S; Cochois V; Beaudry P; Laplanche JL; Néri C
    J Neurosci; 2010 Apr; 30(15):5394-403. PubMed ID: 20392961
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosis.
    Benitez BA; Alvarado D; Cai Y; Mayo K; Chakraverty S; Norton J; Morris JC; Sands MS; Goate A; Cruchaga C
    PLoS One; 2011; 6(11):e26741. PubMed ID: 22073189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.
    Naseri NN; Ergel B; Kharel P; Na Y; Huang Q; Huang R; Dolzhanskaya N; Burré J; Velinov MT; Sharma M
    Nat Struct Mol Biol; 2020 Feb; 27(2):192-201. PubMed ID: 32042150
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SIR2 calls upon the ER.
    Tatar M
    Cell Metab; 2005 Nov; 2(5):281-2. PubMed ID: 16271528
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.
    Parker JA; Arango M; Abderrahmane S; Lambert E; Tourette C; Catoire H; Néri C
    Nat Genet; 2005 Apr; 37(4):349-50. PubMed ID: 15793589
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.