477 related articles for article (PubMed ID: 24949977)
1. Glucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cycles.
Kirschke E; Goswami D; Southworth D; Griffin PR; Agard DA
Cell; 2014 Jun; 157(7):1685-97. PubMed ID: 24949977
[TBL] [Abstract][Full Text] [Related]
2. Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism.
Wang RY; Noddings CM; Kirschke E; Myasnikov AG; Johnson JL; Agard DA
Nature; 2022 Jan; 601(7893):460-464. PubMed ID: 34937942
[TBL] [Abstract][Full Text] [Related]
3. The switch from client holding to folding in the Hsp70/Hsp90 chaperone machineries is regulated by a direct interplay between co-chaperones.
Dahiya V; Rutz DA; Moessmer P; Mühlhofer M; Lawatscheck J; Rief M; Buchner J
Mol Cell; 2022 Apr; 82(8):1543-1556.e6. PubMed ID: 35176233
[TBL] [Abstract][Full Text] [Related]
4. Evidence for iterative ratcheting of receptor-bound hsp70 between its ATP and ADP conformations during assembly of glucocorticoid receptor.hsp90 heterocomplexes.
Morishima Y; Kanelakis KC; Murphy PJ; Shewach DS; Pratt WB
Biochemistry; 2001 Jan; 40(4):1109-16. PubMed ID: 11170435
[TBL] [Abstract][Full Text] [Related]
5. Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.
Dittmar KD; Demady DR; Stancato LF; Krishna P; Pratt WB
J Biol Chem; 1997 Aug; 272(34):21213-20. PubMed ID: 9261129
[TBL] [Abstract][Full Text] [Related]
6. Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation.
Dittmar KD; Pratt WB
J Biol Chem; 1997 May; 272(20):13047-54. PubMed ID: 9148915
[TBL] [Abstract][Full Text] [Related]
7. Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery.
Kanelakis KC; Morishima Y; Dittmar KD; Galigniana MD; Takayama S; Reed JC; Pratt WB
J Biol Chem; 1999 Nov; 274(48):34134-40. PubMed ID: 10567384
[TBL] [Abstract][Full Text] [Related]
8. The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system.
Morishima Y; Kanelakis KC; Silverstein AM; Dittmar KD; Estrada L; Pratt WB
J Biol Chem; 2000 Mar; 275(10):6894-900. PubMed ID: 10702249
[TBL] [Abstract][Full Text] [Related]
9. Structure of Hsp90-p23-GR reveals the Hsp90 client-remodelling mechanism.
Noddings CM; Wang RY; Johnson JL; Agard DA
Nature; 2022 Jan; 601(7893):465-469. PubMed ID: 34937936
[TBL] [Abstract][Full Text] [Related]
10. Stimulation of the weak ATPase activity of human hsp90 by a client protein.
McLaughlin SH; Smith HW; Jackson SE
J Mol Biol; 2002 Jan; 315(4):787-98. PubMed ID: 11812147
[TBL] [Abstract][Full Text] [Related]
11. The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.
Dittmar KD; Banach M; Galigniana MD; Pratt WB
J Biol Chem; 1998 Mar; 273(13):7358-66. PubMed ID: 9516432
[TBL] [Abstract][Full Text] [Related]
12. Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.
Brychzy A; Rein T; Winklhofer KF; Hartl FU; Young JC; Obermann WM
EMBO J; 2003 Jul; 22(14):3613-23. PubMed ID: 12853476
[TBL] [Abstract][Full Text] [Related]
13. Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket.
Morishima Y; Murphy PJ; Li DP; Sanchez ER; Pratt WB
J Biol Chem; 2000 Jun; 275(24):18054-60. PubMed ID: 10764743
[TBL] [Abstract][Full Text] [Related]
14. Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly.
Kanelakis KC; Shewach DS; Pratt WB
J Biol Chem; 2002 Sep; 277(37):33698-703. PubMed ID: 12093808
[TBL] [Abstract][Full Text] [Related]
15. Biochemical reconstitution of steroid receptor•Hsp90 protein complexes and reactivation of ligand binding.
Murphy PJ; Franklin HR; Furukawa NW
J Vis Exp; 2011 Sep; (55):. PubMed ID: 21968922
[TBL] [Abstract][Full Text] [Related]
16. Structural characterization of the substrate transfer mechanism in Hsp70/Hsp90 folding machinery mediated by Hop.
Alvira S; Cuéllar J; Röhl A; Yamamoto S; Itoh H; Alfonso C; Rivas G; Buchner J; Valpuesta JM
Nat Commun; 2014 Nov; 5():5484. PubMed ID: 25407331
[TBL] [Abstract][Full Text] [Related]
17. Ability of various members of the hsp70 family of chaperones to promote assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.
Hutchison KA; Dittmar KD; Stancato LF; Pratt WB
J Steroid Biochem Mol Biol; 1996 Jun; 58(3):251-8. PubMed ID: 8836160
[TBL] [Abstract][Full Text] [Related]
18. The Hsp70-Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration.
Bhattacharya K; Picard D
Cell Mol Life Sci; 2021 Dec; 78(23):7257-7273. PubMed ID: 34677645
[TBL] [Abstract][Full Text] [Related]
19. The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex.
Hernández MP; Sullivan WP; Toft DO
J Biol Chem; 2002 Oct; 277(41):38294-304. PubMed ID: 12161444
[TBL] [Abstract][Full Text] [Related]
20. Chaperone Activity and Dimerization Properties of Hsp90
Morishima Y; Mehta RK; Yoshimura M; Lau M; Southworth DR; Lawrence TS; Pratt WB; Nyati MK; Osawa Y
Mol Pharmacol; 2018 Sep; 94(3):984-991. PubMed ID: 29941666
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
