226 related articles for article (PubMed ID: 24953819)
1. Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.
Copeland KW; Boezio AA; Cheung E; Lee J; Olivieri P; Schenkel LB; Wan Q; Wang W; Wells MC; Youngblood B; Gavva NR; Lehto SG; Geuns-Meyer S
Bioorg Med Chem Lett; 2014 Aug; 24(15):3464-8. PubMed ID: 24953819
[TBL] [Abstract][Full Text] [Related]
2. Activation of transient receptor potential ankyrin 1 by eugenol.
Chung G; Im ST; Kim YH; Jung SJ; Rhyu MR; Oh SB
Neuroscience; 2014 Mar; 261():153-60. PubMed ID: 24384226
[TBL] [Abstract][Full Text] [Related]
3. Tricyclic 3,4-dihydropyrimidine-2-thione derivatives as potent TRPA1 antagonists.
Gijsen HJ; Berthelot D; De Cleyn MA; Geuens I; Brône B; Mercken M
Bioorg Med Chem Lett; 2012 Jan; 22(2):797-800. PubMed ID: 22222037
[TBL] [Abstract][Full Text] [Related]
4. 7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Baraldi PG; Romagnoli R; Saponaro G; Aghazadeh Tabrizi M; Baraldi S; Pedretti P; Fusi C; Nassini R; Materazzi S; Geppetti P; Preti D
Bioorg Med Chem; 2012 Mar; 20(5):1690-8. PubMed ID: 22325155
[TBL] [Abstract][Full Text] [Related]
5. Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: sustained activation of the TRPA1 channel contributes to the pathogenesis of peripheral diabetic neuropathy.
Koivisto A; Hukkanen M; Saarnilehto M; Chapman H; Kuokkanen K; Wei H; Viisanen H; Akerman KE; Lindstedt K; Pertovaara A
Pharmacol Res; 2012 Jan; 65(1):149-58. PubMed ID: 22133672
[TBL] [Abstract][Full Text] [Related]
6. TRPA1 antagonists as potential analgesic drugs.
Andrade EL; Meotti FC; Calixto JB
Pharmacol Ther; 2012 Feb; 133(2):189-204. PubMed ID: 22119554
[TBL] [Abstract][Full Text] [Related]
7. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain.
Wang S; Zhai C; Zhang Y; Yu Y; Zhang Y; Ma L; Li S; Qiao Y
Molecules; 2016 Aug; 21(9):. PubMed ID: 27589700
[TBL] [Abstract][Full Text] [Related]
8. Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative.
Yassaka RT; Inagaki H; Fujino T; Nakatani K; Kubo T
Neurosci Res; 2010 Jan; 66(1):99-105. PubMed ID: 19808063
[TBL] [Abstract][Full Text] [Related]
9. Mouse monoclonal antibodies to transient receptor potential ankyrin 1 act as antagonists of multiple modes of channel activation.
Lee KJ; Wang W; Padaki R; Bi V; Plewa CA; Gavva NR
J Pharmacol Exp Ther; 2014 Aug; 350(2):223-31. PubMed ID: 24893987
[TBL] [Abstract][Full Text] [Related]
10. A novel 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanal oxime compound is a potent Transient Receptor Potential Ankyrin 1 and Vanilloid 1 (TRPA1 and V1) receptor antagonist.
Payrits M; Sághy É; Mátyus P; Czompa A; Ludmerczki R; Deme R; Sándor Z; Helyes Z; Szőke É
Neuroscience; 2016 Jun; 324():151-62. PubMed ID: 26930003
[TBL] [Abstract][Full Text] [Related]
11. Activation of TRPA1 by luminal stimuli induces EP4-mediated anion secretion in human and rat colon.
Kaji I; Yasuoka Y; Karaki S; Kuwahara A
Am J Physiol Gastrointest Liver Physiol; 2012 Apr; 302(7):G690-701. PubMed ID: 22207576
[TBL] [Abstract][Full Text] [Related]
12. Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation.
Chen J; Joshi SK; DiDomenico S; Perner RJ; Mikusa JP; Gauvin DM; Segreti JA; Han P; Zhang XF; Niforatos W; Bianchi BR; Baker SJ; Zhong C; Simler GH; McDonald HA; Schmidt RG; McGaraughty SP; Chu KL; Faltynek CR; Kort ME; Reilly RM; Kym PR
Pain; 2011 May; 152(5):1165-1172. PubMed ID: 21402443
[TBL] [Abstract][Full Text] [Related]
13. Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity.
Schenkel LB; Olivieri PR; Boezio AA; Deak HL; Emkey R; Graceffa RF; Gunaydin H; Guzman-Perez A; Lee JH; Teffera Y; Wang W; Youngblood BD; Yu VL; Zhang M; Gavva NR; Lehto SG; Geuns-Meyer S
J Med Chem; 2016 Mar; 59(6):2794-809. PubMed ID: 26942860
[TBL] [Abstract][Full Text] [Related]
14. Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels.
Oguri G; Nakajima T; Yamamoto Y; Takano N; Tanaka T; Kikuchi H; Morita T; Nakamura F; Yamasoba T; Komuro I
Am J Physiol Heart Circ Physiol; 2014 Nov; 307(9):H1339-52. PubMed ID: 25172898
[TBL] [Abstract][Full Text] [Related]
15. TRPA1 modulators in preclinical development.
Viana F; Ferrer-Montiel A
Expert Opin Ther Pat; 2009 Dec; 19(12):1787-99. PubMed ID: 19939193
[TBL] [Abstract][Full Text] [Related]
16. 2-Amino-4-arylthiazole compounds as TRPA1 antagonists (WO 2012085662): a patent evaluation.
De Petrocellis L; Schiano Moriello A
Expert Opin Ther Pat; 2013 Jan; 23(1):119-47. PubMed ID: 23126422
[TBL] [Abstract][Full Text] [Related]
17. Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.
Mukhopadhyay I; Gomes P; Aranake S; Shetty M; Karnik P; Damle M; Kuruganti S; Thorat S; Khairatkar-Joshi N
J Recept Signal Transduct Res; 2011 Oct; 31(5):350-8. PubMed ID: 21848366
[TBL] [Abstract][Full Text] [Related]
18. Recent advances in the biology and medicinal chemistry of TRPA1.
Rech JC; Eckert WA; Maher MP; Banke T; Bhattacharya A; Wickenden AD
Future Med Chem; 2010 May; 2(5):843-58. PubMed ID: 21426205
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor.
Nakao S; Mabuchi M; Wang S; Kogure Y; Shimizu T; Noguchi K; Tanaka A; Dai Y
Bioorg Med Chem Lett; 2017 Jul; 27(14):3167-3172. PubMed ID: 28576617
[TBL] [Abstract][Full Text] [Related]
20. Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3'-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597).
Niforatos W; Zhang XF; Lake MR; Walter KA; Neelands T; Holzman TF; Scott VE; Faltynek CR; Moreland RB; Chen J
Mol Pharmacol; 2007 May; 71(5):1209-16. PubMed ID: 17314320
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
