BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 24954008)

  • 1. Folate pathway disruption leads to critical disruption of methionine derivatives in Mycobacterium tuberculosis.
    Nixon MR; Saionz KW; Koo MS; Szymonifka MJ; Jung H; Roberts JP; Nandakumar M; Kumar A; Liao R; Rustad T; Sacchettini JC; Rhee KY; Freundlich JS; Sherman DR
    Chem Biol; 2014 Jul; 21(7):819-30. PubMed ID: 24954008
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
    Hajian B; Scocchera E; Shoen C; Krucinska J; Viswanathan K; G-Dayanandan N; Erlandsen H; Estrada A; Mikušová K; Korduláková J; Cynamon M; Wright D
    Cell Chem Biol; 2019 Jun; 26(6):781-791.e6. PubMed ID: 30930162
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase.
    Gerum AB; Ulmer JE; Jacobus DP; Jensen NP; Sherman DR; Sibley CH
    Antimicrob Agents Chemother; 2002 Nov; 46(11):3362-9. PubMed ID: 12384337
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rational drug design, synthesis and biological evaluation of dihydrofolate reductase inhibitors as antituberculosis agents.
    Tawari NR; Bag S; Raju A; Lele AC; Bairwa R; Ray MK; Rajan MG; Nawale LU; Sarkar D; Degani MS
    Future Med Chem; 2015; 7(8):979-88. PubMed ID: 26062396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans.
    Navarro-Martínez MD; García-Cánovas F; Rodríguez-López JN
    J Antimicrob Chemother; 2006 Jun; 57(6):1083-92. PubMed ID: 16585130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis.
    Chakraborty S; Gruber T; Barry CE; Boshoff HI; Rhee KY
    Science; 2013 Jan; 339(6115):88-91. PubMed ID: 23118010
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates.
    Thiede JM; Kordus SL; Turman BJ; Buonomo JA; Aldrich CC; Minato Y; Baughn AD
    Sci Rep; 2016 Dec; 6():38083. PubMed ID: 27905500
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interactions of 5-deazapteridine derivatives with Mycobacterium tuberculosis and with human dihydrofolate reductases.
    da Cunha EF; de Castro Ramalho T; Bicca de Alencastro R; Maia ER
    J Biomol Struct Dyn; 2004 Oct; 22(2):119-30. PubMed ID: 15317473
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis.
    El-Hamamsy MH; Smith AW; Thompson AS; Threadgill MD
    Bioorg Med Chem; 2007 Jul; 15(13):4552-76. PubMed ID: 17451962
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fragment Discovery for the Design of Nitrogen Heterocycles as Mycobacterium tuberculosis Dihydrofolate Reductase Inhibitors.
    Shelke RU; Degani MS; Raju A; Ray MK; Rajan MG
    Arch Pharm (Weinheim); 2016 Aug; 349(8):602-13. PubMed ID: 27320965
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potency boost of a
    Aragaw WW; Lee BM; Yang X; Zimmerman MD; Gengenbacher M; Dartois V; Chui WK; Jackson CJ; Dick T
    Proc Natl Acad Sci U S A; 2021 Jun; 118(25):. PubMed ID: 34161270
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transfection studies to explore essential folate metabolism and antifolate drug synergy in the human malaria parasite Plasmodium falciparum.
    Wang P; Wang Q; Aspinall TV; Sims PF; Hyde JE
    Mol Microbiol; 2004 Mar; 51(5):1425-38. PubMed ID: 14982635
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methionine Antagonizes
    Howe MD; Kordus SL; Cole MS; Bauman AA; Aldrich CC; Baughn AD; Minato Y
    Front Cell Infect Microbiol; 2018; 8():399. PubMed ID: 30483484
    [No Abstract]   [Full Text] [Related]  

  • 14. One of these is not like the others.
    Pavelka MS
    Trends Microbiol; 2015 Nov; 23(11):668-670. PubMed ID: 26439291
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Folate metabolism in malaria.
    Ferone R
    Bull World Health Organ; 1977; 55(2-3):291-8. PubMed ID: 338184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Virtual screening against Mycobacterium tuberculosis dihydrofolate reductase: suggested workflow for compound prioritization using structure interaction fingerprints.
    Kumar A; Siddiqi MI
    J Mol Graph Model; 2008 Nov; 27(4):476-88. PubMed ID: 18829358
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Folic acid metabolism and its disruption by pharmacologic agents.
    Huennekens FM; Duffy TH; Vitols KS
    NCI Monogr; 1987; (5):1-8. PubMed ID: 3124003
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of novel DHFR inhibitors for treatment of tuberculosis by combining virtual screening with in vitro activity assay.
    Wang N; Ren JX; Xie Y
    J Biomol Struct Dyn; 2019 Mar; 37(4):1054-1061. PubMed ID: 29504455
    [No Abstract]   [Full Text] [Related]  

  • 19. Folate Pathway Inhibitors, An Underestimated and Underexplored Molecular Target for New Anti-tuberculosis Agents.
    Vassiliades SV; Borges LG; Giarolla J; Parise-Filho R
    Mini Rev Med Chem; 2023; 23(17):1711-1732. PubMed ID: 36744693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New Mycobacterium avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors.
    Suling WJ; Seitz LE; Reynolds RC; Barrow WW
    Antimicrob Agents Chemother; 2005 Nov; 49(11):4801-3. PubMed ID: 16251337
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.