These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
213 related articles for article (PubMed ID: 24954548)
21. Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75. Cuzzucoli Crucitti G; Pescatori L; Messore A; Madia VN; Pupo G; Saccoliti F; Scipione L; Tortorella S; Di Leva FS; Cosconati S; Novellino E; Debyser Z; Christ F; Costi R; Di Santo R Eur J Med Chem; 2015 Aug; 101():288-94. PubMed ID: 26150289 [TBL] [Abstract][Full Text] [Related]
22. The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75. Zhang DW; Yan HL; Xu XS; Xu L; Yin ZH; Chang S; Luo H J Enzyme Inhib Med Chem; 2020 Dec; 35(1):906-912. PubMed ID: 32228103 [TBL] [Abstract][Full Text] [Related]
23. Structural basis for the potent inhibition of the HIV integrase-LEDGF/p75 protein-protein interaction. Ribone SR; Quevedo MA J Mol Graph Model; 2017 Aug; 75():189-198. PubMed ID: 28582696 [TBL] [Abstract][Full Text] [Related]
24. Inhibition of the interaction between HIV-1 integrase and its cofactor LEDGF/p75: a promising approach in anti-retroviral therapy. De Luca L; Ferro S; Morreale F; Chimirri A Mini Rev Med Chem; 2011 Jul; 11(8):714-27. PubMed ID: 21651465 [TBL] [Abstract][Full Text] [Related]
25. Fragment hopping approach directed at design of HIV IN-LEDGF/p75 interaction inhibitors. De Luca L; Ferro S; Morreale F; Christ F; Debyser Z; Chimirri A; Gitto R J Enzyme Inhib Med Chem; 2013 Oct; 28(5):1002-9. PubMed ID: 22803661 [TBL] [Abstract][Full Text] [Related]
26. The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity. Amadori C; van der Velden YU; Bonnard D; Orlov I; van Bel N; Le Rouzic E; Miralles L; Brias J; Chevreuil F; Spehner D; Chasset S; Ledoussal B; Mayr L; Moreau F; García F; Gatell J; Zamborlini A; Emiliani S; Ruff M; Klaholz BP; Moog C; Berkhout B; Plana M; Benarous R Retrovirology; 2017 Nov; 14(1):50. PubMed ID: 29121950 [TBL] [Abstract][Full Text] [Related]
27. Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction. Serrao E; Xu ZL; Debnath B; Christ F; Debyser Z; Long YQ; Neamati N Bioorg Med Chem; 2013 Oct; 21(19):5963-72. PubMed ID: 23985689 [TBL] [Abstract][Full Text] [Related]
28. Insights into the interactions between HIV-1 integrase and human LEDGF/p75 by molecular dynamics simulation and free energy calculation. Zhao Y; Li W; Zeng J; Liu G; Tang Y Proteins; 2008 Aug; 72(2):635-45. PubMed ID: 18247352 [TBL] [Abstract][Full Text] [Related]
29. In vitro DNA tethering of HIV-1 integrase by the transcriptional coactivator LEDGF/p75. McNeely M; Hendrix J; Busschots K; Boons E; Deleersnijder A; Gerard M; Christ F; Debyser Z J Mol Biol; 2011 Jul; 410(5):811-30. PubMed ID: 21763490 [TBL] [Abstract][Full Text] [Related]
30. Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation. Esposito F; Tintori C; Martini R; Christ F; Debyser Z; Ferrarese R; Cabiddu G; Corona A; Ceresola ER; Calcaterra A; Iovine V; Botta B; Clementi M; Canducci F; Botta M; Tramontano E Chembiochem; 2015 Nov; 16(17):2507-12. PubMed ID: 26360521 [TBL] [Abstract][Full Text] [Related]
31. Wikstroelide M potently inhibits HIV replication by targeting reverse transcriptase and integrase nuclear translocation. Zhang X; Huang SZ; Gu WG; Yang LM; Chen H; Zheng CB; Zhao YX; Wan DC; Zheng YT Chin J Nat Med; 2014 Mar; 12(3):186-93. PubMed ID: 24702804 [TBL] [Abstract][Full Text] [Related]
32. Evaluation of a flavonoid library for inhibition of interaction of HIV-1 integrase with human LEDGF/p75 towards a structure-activity relationship. Yin ZH; Yan HL; Pan Y; Zhang DW; Yan X Ann Med; 2022 Dec; 54(1):1590-1600. PubMed ID: 35658757 [No Abstract] [Full Text] [Related]
33. Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor. Cavalluzzo C; Christ F; Voet A; Sharma A; Singh BK; Zhang KY; Lescrinier E; De Maeyer M; Debyser Z; Van der Eycken E J Pept Sci; 2013 Oct; 19(10):651-8. PubMed ID: 24014475 [TBL] [Abstract][Full Text] [Related]
34. Quinoline-based Protein-protein Interaction Inhibitors of LEDGF/p75 and HIV Integrase: An In Silico Study. Chhokar N; Kalra S; Chauhan M; Munshi A; Kumar R Curr Top Med Chem; 2018; 18(32):2800-2815. PubMed ID: 30747071 [TBL] [Abstract][Full Text] [Related]
35. HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin. Astiazaran P; Bueno MT; Morales E; Kugelman JR; Garcia-Rivera JA; Llano M Retrovirology; 2011 Apr; 8():27. PubMed ID: 21510906 [TBL] [Abstract][Full Text] [Related]
36. Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV. Hombrouck A; De Rijck J; Hendrix J; Vandekerckhove L; Voet A; De Maeyer M; Witvrouw M; Engelborghs Y; Christ F; Gijsbers R; Debyser Z PLoS Pathog; 2007 Mar; 3(3):e47. PubMed ID: 17397262 [TBL] [Abstract][Full Text] [Related]
37. Effective prediction model and determination of binding residues influential for inhibitors targeting HIV-1 integrase-LEDGF/p75 interface by employing solvent accessible surface area energy as key determinant. Thangsunan P; Wongsaipun S; Kittiwachana S; Suree N J Biomol Struct Dyn; 2020 Feb; 38(2):460-473. PubMed ID: 30744499 [TBL] [Abstract][Full Text] [Related]
38. Discovery of a Novel HIV-1 Integrase/p75 Interacting Inhibitor by Docking Screening, Biochemical Assay, and in Vitro Studies. Wang Y; Lin HQ; Wang P; Hu JS; Ip TM; Yang LM; Zheng YT; Chi-Cheong Wan D J Chem Inf Model; 2017 Sep; 57(9):2336-2343. PubMed ID: 28837332 [TBL] [Abstract][Full Text] [Related]
39. Computational studies of the interaction between the HIV-1 integrase tetramer and the cofactor LEDGF/p75: insights from molecular dynamics simulations and the informational spectrum method. Tintori C; Veljkovic N; Veljkovic V; Botta M Proteins; 2010 Dec; 78(16):3396-408. PubMed ID: 20878714 [TBL] [Abstract][Full Text] [Related]
40. Recent Advances in the Development of Small-Molecular Inhibitors Target HIV Integrase-LEDGF/p75 Interaction. Zhao Y; Luo Z Mini Rev Med Chem; 2015; 15(14):1195-208. PubMed ID: 26156421 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]