BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

455 related articles for article (PubMed ID: 24956016)

  • 1. Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension.
    Gore B; Izikki M; Mercier O; Dewachter L; Fadel E; Humbert M; Dartevelle P; Simonneau G; Naeije R; Lebrin F; Eddahibi S
    PLoS One; 2014; 9(6):e100310. PubMed ID: 24956016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway.
    Pece-Barbara N; Vera S; Kathirkamathamby K; Liebner S; Di Guglielmo GM; Dejana E; Wrana JL; Letarte M
    J Biol Chem; 2005 Jul; 280(30):27800-8. PubMed ID: 15923183
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.
    Mahmoud M; Borthwick GM; Hislop AA; Arthur HM
    Lab Invest; 2009 Jan; 89(1):15-25. PubMed ID: 19015642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SnoN facilitates ALK1-Smad1/5 signaling during embryonic angiogenesis.
    Zhu Q; Kim YH; Wang D; Oh SP; Luo K
    J Cell Biol; 2013 Sep; 202(6):937-50. PubMed ID: 24019535
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.
    Lebrin F; Goumans MJ; Jonker L; Carvalho RL; Valdimarsdottir G; Thorikay M; Mummery C; Arthur HM; ten Dijke P
    EMBO J; 2004 Oct; 23(20):4018-28. PubMed ID: 15385967
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies.
    Nolan-Stevaux O; Zhong W; Culp S; Shaffer K; Hoover J; Wickramasinghe D; Ruefli-Brasse A
    PLoS One; 2012; 7(12):e50920. PubMed ID: 23300529
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells.
    Upton PD; Davies RJ; Trembath RC; Morrell NW
    J Biol Chem; 2009 Jun; 284(23):15794-804. PubMed ID: 19366699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transforming growth factor-β stimulates Smad1/5 signaling in pulmonary artery smooth muscle cells and fibroblasts of the newborn mouse through ALK1.
    Zhang H; Du L; Zhong Y; Flanders KC; Roberts JD
    Am J Physiol Lung Cell Mol Physiol; 2017 Sep; 313(3):L615-L627. PubMed ID: 28642261
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis.
    Oh SP; Seki T; Goss KA; Imamura T; Yi Y; Donahoe PK; Li L; Miyazono K; ten Dijke P; Kim S; Li E
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2626-31. PubMed ID: 10716993
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease.
    Long L; Crosby A; Yang X; Southwood M; Upton PD; Kim DK; Morrell NW
    Circulation; 2009 Feb; 119(4):566-76. PubMed ID: 19153267
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-β in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension.
    Tojais NF; Cao A; Lai YJ; Wang L; Chen PI; Alcazar MAA; de Jesus Perez VA; Hopper RK; Rhodes CJ; Bill MA; Sakai LY; Rabinovitch M
    Arterioscler Thromb Vasc Biol; 2017 Aug; 37(8):1559-1569. PubMed ID: 28619995
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hereditary hemorrhagic telangiectasia, a vascular dysplasia affecting the TGF-beta signaling pathway.
    Fernández-L A; Sanz-Rodriguez F; Blanco FJ; Bernabéu C; Botella LM
    Clin Med Res; 2006 Mar; 4(1):66-78. PubMed ID: 16595794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts.
    Morris E; Chrobak I; Bujor A; Hant F; Mummery C; Ten Dijke P; Trojanowska M
    J Cell Physiol; 2011 Dec; 226(12):3340-8. PubMed ID: 21344387
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration.
    Ray BN; Lee NY; How T; Blobe GC
    Carcinogenesis; 2010 Mar; 31(3):435-41. PubMed ID: 20042635
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ALK1 regulates the internalization of endoglin and the type III TGF-β receptor.
    Tazat K; Pomeraniec-Abudy L; Hector-Greene M; Szilágyi SS; Sharma S; Cai EM; Corona AL; Ehrlich M; Blobe GC; Henis YI
    Mol Biol Cell; 2021 Apr; 32(7):605-621. PubMed ID: 33566682
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.
    Finnson KW; Parker WL; ten Dijke P; Thorikay M; Philip A
    J Bone Miner Res; 2008 Jun; 23(6):896-906. PubMed ID: 18333754
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling.
    Scherner O; Meurer SK; Tihaa L; Gressner AM; Weiskirchen R
    J Biol Chem; 2007 May; 282(19):13934-43. PubMed ID: 17376778
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
    Biasin V; Chwalek K; Wilhelm J; Best J; Marsh LM; Ghanim B; Klepetko W; Fink L; Schermuly RT; Weissmann N; Olschewski A; Kwapiszewska G
    Int J Biochem Cell Biol; 2014 Sep; 54():137-48. PubMed ID: 25016214
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of Activin Receptor-Like Kinase 1 in Endothelial Cells Suppresses Development of Arteriovenous Malformations in Mouse Models of Hereditary Hemorrhagic Telangiectasia.
    Hwan Kim Y; Vu PN; Choe SW; Jeon CJ; Arthur HM; Vary CPH; Lee YJ; Oh SP
    Circ Res; 2020 Oct; 127(9):1122-1137. PubMed ID: 32762495
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endothelial cells are activated during hypoxia via endoglin/ALK-1/SMAD1/5 signaling in vivo and in vitro.
    Tian F; Zhou AX; Smits AM; Larsson E; Goumans MJ; Heldin CH; Borén J; Akyürek LM
    Biochem Biophys Res Commun; 2010 Feb; 392(3):283-8. PubMed ID: 20060813
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.