BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 24956219)

  • 1. Deletion of FoxO1 leads to shortening of QRS by increasing Na(+) channel activity through enhanced expression of both cardiac NaV1.5 and β3 subunit.
    Cai B; Wang N; Mao W; You T; Lu Y; Li X; Ye B; Li F; Xu H
    J Mol Cell Cardiol; 2014 Sep; 74():297-306. PubMed ID: 24956219
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reactive oxygen species suppress cardiac NaV1.5 expression through Foxo1.
    Mao W; You T; Ye B; Li X; Dong HH; Hill JA; Li F; Xu H
    PLoS One; 2012; 7(2):e32738. PubMed ID: 22400069
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhancement of β-catenin/T-cell factor 4 signaling causes susceptibility to cardiac arrhythmia by suppressing Na
    Huo R; Hu C; Zhao L; Sun L; Wang N; Lu Y; Ye B; Deb A; Li F; Xu H
    Heart Rhythm; 2019 Nov; 16(11):1720-1728. PubMed ID: 31125668
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deletion of PDK1 causes cardiac sodium current reduction in mice.
    Han Z; Jiang Y; Yang Y; Li X; Yang Z; Cao K; Wang DW
    PLoS One; 2015; 10(3):e0122436. PubMed ID: 25781322
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A small-molecule LF3 abrogates β-catenin/TCF4-mediated suppression of Na
    Zhao L; Sun L; Lu Y; Li F; Xu H
    J Mol Cell Cardiol; 2019 Oct; 135():90-96. PubMed ID: 31419437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Elevated EZH2 in ischemic heart disease epigenetically mediates suppression of Na
    Zhao L; You T; Lu Y; Lin S; Li F; Xu H
    J Mol Cell Cardiol; 2021 Apr; 153():95-103. PubMed ID: 33370552
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nitric oxide down-regulates voltage-gated Na
    Wang P; Wei M; Zhu X; Liu Y; Yoshimura K; Zheng M; Liu G; Kume S; Morishima M; Kurokawa T; Ono K
    Sci Rep; 2021 May; 11(1):11273. PubMed ID: 34050231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tetrodotoxin-sensitive α-subunits of voltage-gated sodium channels are relevant for inhibition of cardiac sodium currents by local anesthetics.
    Stoetzer C; Doll T; Stueber T; Herzog C; Echtermeyer F; Greulich F; Rudat C; Kispert A; Wegner F; Leffler A
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Jun; 389(6):625-36. PubMed ID: 27000037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcription factor Meis1 act as a new regulator of ischemic arrhythmias in mice.
    Liu Y; Li J; Xu N; Yu H; Gong L; Li Q; Yang Z; Li S; Yang J; Huang D; Xue Y; Xue G; Liu J; Chen H; Zhang R; Li A; Zhao Y; Li P; Li M; Liu M; Wang N; Cai B
    J Adv Res; 2022 Jul; 39():275-289. PubMed ID: 35777912
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of Wnt/β-catenin signaling by hydrogen peroxide transcriptionally inhibits NaV1.5 expression.
    Wang N; Huo R; Cai B; Lu Y; Ye B; Li X; Li F; Xu H
    Free Radic Biol Med; 2016 Jul; 96():34-44. PubMed ID: 27068063
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The RyR2-P2328S mutation downregulates Nav1.5 producing arrhythmic substrate in murine ventricles.
    Ning F; Luo L; Ahmad S; Valli H; Jeevaratnam K; Wang T; Guzadhur L; Yang D; Fraser JA; Huang CL; Ma A; Salvage SC
    Pflugers Arch; 2016 Apr; 468(4):655-65. PubMed ID: 26545784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biophysical comparison of sodium currents in native cardiac myocytes and human induced pluripotent stem cell-derived cardiomyocytes.
    Goodrow RJ; Desai S; Treat JA; Panama BK; Desai M; Nesterenko VV; Cordeiro JM
    J Pharmacol Toxicol Methods; 2018; 90():19-30. PubMed ID: 29128504
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome.
    Nieto-Marín P; Tinaquero D; Utrilla RG; Cebrián J; González-Guerra A; Crespo-García T; Cámara-Checa A; Rubio-Alarcón M; Dago M; Alfayate S; Filgueiras-Rama D; Peinado R; López-Sendón JL; Jalife J; Tamargo J; Bernal JA; Caballero R; Delpón E;
    Cardiovasc Res; 2022 Mar; 118(4):1046-1060. PubMed ID: 33576403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. β1 and β3 subunits amplify mechanosensitivity of the cardiac voltage-gated sodium channel Nav1.5.
    Maroni M; Körner J; Schüttler J; Winner B; Lampert A; Eberhardt E
    Pflugers Arch; 2019 Dec; 471(11-12):1481-1492. PubMed ID: 31728700
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility.
    Schroder EA; Lefta M; Zhang X; Bartos DC; Feng HZ; Zhao Y; Patwardhan A; Jin JP; Esser KA; Delisle BP
    Am J Physiol Cell Physiol; 2013 May; 304(10):C954-65. PubMed ID: 23364267
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transforming growth factor β receptor inhibition prevents ventricular fibrosis in a mouse model of progressive cardiac conduction disease.
    Derangeon M; Montnach J; Cerpa CO; Jagu B; Patin J; Toumaniantz G; Girardeau A; Huang CLH; Colledge WH; Grace AA; Baró I; Charpentier F
    Cardiovasc Res; 2017 Apr; 113(5):464-474. PubMed ID: 28339646
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Changes in cardiac Nav1.5 expression, function, and acetylation by pan-histone deacetylase inhibitors.
    Xu Q; Patel D; Zhang X; Veenstra RD
    Am J Physiol Heart Circ Physiol; 2016 Nov; 311(5):H1139-H1149. PubMed ID: 27638876
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.
    Vikram A; Lewarchik CM; Yoon JY; Naqvi A; Kumar S; Morgan GM; Jacobs JS; Li Q; Kim YR; Kassan M; Liu J; Gabani M; Kumar A; Mehdi H; Zhu X; Guan X; Kutschke W; Zhang X; Boudreau RL; Dai S; Matasic DS; Jung SB; Margulies KB; Kumar V; Bachschmid MM; London B; Irani K
    Nat Med; 2017 Mar; 23(3):361-367. PubMed ID: 28191886
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Variant Intronic Enhancer Controls
    Man JCK; Bosada FM; Scholman KT; Offerhaus JA; Walsh R; van Duijvenboden K; van Eif VWW; Bezzina CR; Verkerk AO; Boukens BJ; Barnett P; Christoffels VM
    Circulation; 2021 Jul; 144(3):229-242. PubMed ID: 33910361
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
    Musa H; Kline CF; Sturm AC; Murphy N; Adelman S; Wang C; Yan H; Johnson BL; Csepe TA; Kilic A; Higgins RS; Janssen PM; Fedorov VV; Weiss R; Salazar C; Hund TJ; Pitt GS; Mohler PJ
    Proc Natl Acad Sci U S A; 2015 Oct; 112(40):12528-33. PubMed ID: 26392562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.