BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 24958101)

  • 1. Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
    Siu KT; Xu Y; Swartz KL; Bhattacharyya M; Gurbuxani S; Hua Y; Minella AC
    Mol Cell Biol; 2014 Sep; 34(17):3244-58. PubMed ID: 24958101
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7.
    Thompson BJ; Jankovic V; Gao J; Buonamici S; Vest A; Lee JM; Zavadil J; Nimer SD; Aifantis I
    J Exp Med; 2008 Jun; 205(6):1395-408. PubMed ID: 18474632
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
    Xu Y; Sengupta T; Kukreja L; Minella AC
    J Biol Chem; 2010 Nov; 285(45):34439-46. PubMed ID: 20826802
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.
    Minella AC; Loeb KR; Knecht A; Welcker M; Varnum-Finney BJ; Bernstein ID; Roberts JM; Clurman BE
    Genes Dev; 2008 Jun; 22(12):1677-89. PubMed ID: 18559482
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras activity regulates cyclin E degradation by the Fbw7 pathway.
    Minella AC; Welcker M; Clurman BE
    Proc Natl Acad Sci U S A; 2005 Jul; 102(27):9649-54. PubMed ID: 15980150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression.
    Lerner M; Lundgren J; Akhoondi S; Jahn A; Ng HF; Akbari Moqadam F; Oude Vrielink JA; Agami R; Den Boer ML; Grandér D; Sangfelt O
    Cell Cycle; 2011 Jul; 10(13):2172-83. PubMed ID: 21597324
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
    Tu K; Zheng X; Zhou Z; Li C; Zhang J; Gao J; Yao Y; Liu Q
    PLoS One; 2013; 8(7):e68574. PubMed ID: 23840897
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.
    Grim JE; Knoblaugh SE; Guthrie KA; Hagar A; Swanger J; Hespelt J; Delrow JJ; Small T; Grady WM; Nakayama KI; Clurman BE
    Mol Cell Biol; 2012 Jun; 32(11):2160-7. PubMed ID: 22473991
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.
    Bhaskaran N; van Drogen F; Ng HF; Kumar R; Ekholm-Reed S; Peter M; Sangfelt O; Reed SI
    Mol Cell Biol; 2013 Jan; 33(1):85-97. PubMed ID: 23109421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.
    Takada M; Zhang W; Suzuki A; Kuroda TS; Yu Z; Inuzuka H; Gao D; Wan L; Zhuang M; Hu L; Zhai B; Fry CJ; Bloom K; Li G; Karpen GH; Wei W; Zhang Q
    Cancer Res; 2017 Sep; 77(18):4881-4893. PubMed ID: 28760857
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.
    Tron AE; Arai T; Duda DM; Kuwabara H; Olszewski JL; Fujiwara Y; Bahamon BN; Signoretti S; Schulman BA; DeCaprio JA
    Mol Cell; 2012 Apr; 46(1):67-78. PubMed ID: 22405651
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T; Hattori T; Kitagawa K; Uchida C; Kotake Y; Kosugi I; Oda T; Kitagawa M
    J Biol Chem; 2009 Oct; 284(41):27766-27779. PubMed ID: 19679664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
    Yada M; Hatakeyama S; Kamura T; Nishiyama M; Tsunematsu R; Imaki H; Ishida N; Okumura F; Nakayama K; Nakayama KI
    EMBO J; 2004 May; 23(10):2116-25. PubMed ID: 15103331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism.
    Xu Y; Swartz KL; Siu KT; Bhattacharyya M; Minella AC
    Oncogene; 2014 Jun; 33(24):3161-71. PubMed ID: 23873023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differences in degradation lead to asynchronous expression of cyclin E1 and cyclin E2 in cancer cells.
    Caldon CE; Sergio CM; Sutherland RL; Musgrove EA
    Cell Cycle; 2013 Feb; 12(4):596-605. PubMed ID: 23324394
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An integrated view of cyclin E function and regulation.
    Siu KT; Rosner MR; Minella AC
    Cell Cycle; 2012 Jan; 11(1):57-64. PubMed ID: 22186781
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H; Shaik S; Onoyama I; Gao D; Tseng A; Maser RS; Zhai B; Wan L; Gutierrez A; Lau AW; Xiao Y; Christie AL; Aster J; Settleman J; Gygi SP; Kung AL; Look T; Nakayama KI; DePinho RA; Wei W
    Nature; 2011 Mar; 471(7336):104-9. PubMed ID: 21368833
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fbw7 isoform interaction contributes to cyclin E proteolysis.
    Zhang W; Koepp DM
    Mol Cancer Res; 2006 Dec; 4(12):935-43. PubMed ID: 17189384
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.
    Grim JE; Gustafson MP; Hirata RK; Hagar AC; Swanger J; Welcker M; Hwang HC; Ericsson J; Russell DW; Clurman BE
    J Cell Biol; 2008 Jun; 181(6):913-20. PubMed ID: 18559665
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.