BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

300 related articles for article (PubMed ID: 24960692)

  • 1. Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors.
    Forget A; Bihannic L; Cigna SM; Lefevre C; Remke M; Barnat M; Dodier S; Shirvani H; Mercier A; Mensah A; Garcia M; Humbert S; Taylor MD; Lasorella A; Ayrault O
    Dev Cell; 2014 Jun; 29(6):649-61. PubMed ID: 24960692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
    Chang CH; Zanini M; Shirvani H; Cheng JS; Yu H; Feng CH; Mercier AL; Hung SY; Forget A; Wang CH; Cigna SM; Lu IL; Chen WY; Leboucher S; Wang WJ; Ruat M; Spassky N; Tsai JW; Ayrault O
    Dev Cell; 2019 Jan; 48(2):184-199.e5. PubMed ID: 30695697
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
    Binning MJ; Niazi T; Pedone CA; Lal B; Eberhart CG; Kim KJ; Laterra J; Fults DW
    Cancer Res; 2008 Oct; 68(19):7838-45. PubMed ID: 18829539
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors.
    Kenney AM; Cole MD; Rowitch DH
    Development; 2003 Jan; 130(1):15-28. PubMed ID: 12441288
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.
    Ayrault O; Zhao H; Zindy F; Qu C; Sherr CJ; Roussel MF
    Cancer Res; 2010 Jul; 70(13):5618-27. PubMed ID: 20516124
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas.
    Grausam KB; Dooyema SDR; Bihannic L; Premathilake H; Morrissy AS; Forget A; Schaefer AM; Gundelach JH; Macura S; Maher DM; Wang X; Heglin AH; Ge X; Zeng E; Puget S; Chandrasekar I; Surendran K; Bram RJ; Schüller U; Talyor MD; Ayrault O; Zhao H
    Cancer Res; 2017 Jul; 77(14):3766-3777. PubMed ID: 28490517
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum.
    Heil C
    Open Biol; 2019 Jan; 9(1):180145. PubMed ID: 30958113
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors.
    Parathath SR; Mainwaring LA; Fernandez-L A; Campbell DO; Kenney AM
    Development; 2008 Oct; 135(19):3291-300. PubMed ID: 18755774
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling.
    Ma P; An T; Zhu L; Zhang L; Wang H; Ren B; Sun B; Zhou X; Li Y; Mao B
    Development; 2020 Jun; 147(21):. PubMed ID: 32376680
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.
    Thomas WD; Chen J; Gao YR; Cheung B; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM
    Oncogene; 2009 Apr; 28(13):1605-15. PubMed ID: 19234491
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma.
    Flora A; Klisch TJ; Schuster G; Zoghbi HY
    Science; 2009 Dec; 326(5958):1424-7. PubMed ID: 19965762
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.
    Cheng YF; Tong M; Edge AS
    J Biol Chem; 2016 Sep; 291(40):21096-21109. PubMed ID: 27542412
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Atoh1/MATH1 Adds Up to Ciliogenesis for Transducing SHH Signaling in the Cerebellum.
    Castellino RC; Kenney AM
    Dev Cell; 2019 Jan; 48(2):129-130. PubMed ID: 30695693
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development.
    Zhao H; Ayrault O; Zindy F; Kim JH; Roussel MF
    Genes Dev; 2008 Mar; 22(6):722-7. PubMed ID: 18347090
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
    Northcott PA; Fernandez-L A; Hagan JP; Ellison DW; Grajkowska W; Gillespie Y; Grundy R; Van Meter T; Rutka JT; Croce CM; Kenney AM; Taylor MD
    Cancer Res; 2009 Apr; 69(8):3249-55. PubMed ID: 19351822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation.
    Malek R; Matta J; Taylor N; Perry ME; Mendrysa SM
    PLoS One; 2011 Mar; 6(3):e17884. PubMed ID: 21437245
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stox1 as a novel transcriptional suppressor of Math1 during cerebellar granule neurogenesis and medulloblastoma formation.
    Zhang C; Ji Z; Wang M; Zhang W; Yang R; An H; Yang R; van Abel D; van Dijk M; Yang X; Ou G; Zhu HH; Gao WQ
    Cell Death Differ; 2016 Dec; 23(12):2042-2053. PubMed ID: 27564589
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors.
    Oliver TG; Grasfeder LL; Carroll AL; Kaiser C; Gillingham CL; Lin SM; Wickramasinghe R; Scott MP; Wechsler-Reya RJ
    Proc Natl Acad Sci U S A; 2003 Jun; 100(12):7331-6. PubMed ID: 12777630
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.
    Fogarty MP; Emmenegger BA; Grasfeder LL; Oliver TG; Wechsler-Reya RJ
    Proc Natl Acad Sci U S A; 2007 Feb; 104(8):2973-8. PubMed ID: 17299056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.
    Fernandez-L A; Northcott PA; Dalton J; Fraga C; Ellison D; Angers S; Taylor MD; Kenney AM
    Genes Dev; 2009 Dec; 23(23):2729-41. PubMed ID: 19952108
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.