BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 24963996)

  • 1. Expansion of the aminoglycoside-resistance 16S rRNA (m(1)A1408) methyltransferase family: expression and functional characterization of four hypothetical enzymes of diverse bacterial origin.
    Witek MA; Conn GL
    Biochim Biophys Acta; 2014 Sep; 1844(9):1648-55. PubMed ID: 24963996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression, purification and crystallization of adenosine 1408 aminoglycoside-resistance rRNA methyltransferases for structural studies.
    Zelinskaya N; Rankin CR; Macmaster R; Savic M; Conn GL
    Protein Expr Purif; 2011 Jan; 75(1):89-94. PubMed ID: 20667473
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Pathogen-Derived Aminoglycoside Resistance 16S rRNA Methyltransferase NpmA Possesses Dual m1A1408/m1G1408 Specificity.
    Zelinskaya N; Witek MA; Conn GL
    Antimicrob Agents Chemother; 2015 Dec; 59(12):7862-5. PubMed ID: 26416864
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 30S Subunit-dependent activation of the Sorangium cellulosum So ce56 aminoglycoside resistance-conferring 16S rRNA methyltransferase Kmr.
    Savic M; Sunita S; Zelinskaya N; Desai PM; Macmaster R; Vinal K; Conn GL
    Antimicrob Agents Chemother; 2015 May; 59(5):2807-16. PubMed ID: 25733511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics.
    Savic M; Lovric J; Tomic TI; Vasiljevic B; Conn GL
    Nucleic Acids Res; 2009 Sep; 37(16):5420-31. PubMed ID: 19589804
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition.
    Nosrati M; Dey D; Mehrani A; Strassler SE; Zelinskaya N; Hoffer ED; Stagg SM; Dunham CM; Conn GL
    J Biol Chem; 2019 Nov; 294(46):17642-17653. PubMed ID: 31594862
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.
    Macmaster R; Zelinskaya N; Savic M; Rankin CR; Conn GL
    Nucleic Acids Res; 2010 Nov; 38(21):7791-9. PubMed ID: 20639535
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.
    Wachino J; Shibayama K; Kurokawa H; Kimura K; Yamane K; Suzuki S; Shibata N; Ike Y; Arakawa Y
    Antimicrob Agents Chemother; 2007 Dec; 51(12):4401-9. PubMed ID: 17875999
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
    Husain N; Obranic S; Koscinski L; Seetharaman J; Babic F; Bujnicki JM; Maravic-Vlahovicek G; Sivaraman J
    Nucleic Acids Res; 2011 Mar; 39(5):1903-18. PubMed ID: 21062819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substrate Recognition and Modification by a Pathogen-Associated Aminoglycoside Resistance 16S rRNA Methyltransferase.
    Vinal K; Conn GL
    Antimicrob Agents Chemother; 2017 May; 61(5):. PubMed ID: 28289026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aminoglycoside resistance 16S rRNA methyltransferases block endogenous methylation, affect translation efficiency and fitness of the host.
    Lioy VS; Goussard S; Guerineau V; Yoon EJ; Courvalin P; Galimand M; Grillot-Courvalin C
    RNA; 2014 Mar; 20(3):382-91. PubMed ID: 24398977
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The aminoglycoside resistance methyltransferase Sgm impedes RsmF methylation at an adjacent rRNA nucleotide in the ribosomal A site.
    Cubrilo S; Babić F; Douthwaite S; Maravić Vlahovicek G
    RNA; 2009 Aug; 15(8):1492-7. PubMed ID: 19509304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
    Witek MA; Conn GL
    Nucleic Acids Res; 2016 Jan; 44(1):342-53. PubMed ID: 26609134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heterologous Expression and Functional Characterization of the Exogenously Acquired Aminoglycoside Resistance Methyltransferases RmtD, RmtD2, and RmtG.
    Corrêa LL; Witek MA; Zelinskaya N; Picão RC; Conn GL
    Antimicrob Agents Chemother; 2016 Jan; 60(1):699-702. PubMed ID: 26552988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m5C1404-specific methyltransferase EfmM.
    Galimand M; Schmitt E; Panvert M; Desmolaize B; Douthwaite S; Mechulam Y; Courvalin P
    RNA; 2011 Feb; 17(2):251-62. PubMed ID: 21159796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional and Structural Characterization of Acquired 16S rRNA Methyltransferase NpmB1 Conferring Pan-Aminoglycoside Resistance.
    Kawai A; Suzuki M; Tsukamoto K; Minato Y; Doi Y
    Antimicrob Agents Chemother; 2021 Sep; 65(10):e0100921. PubMed ID: 34310216
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA.
    Kanazawa H; Baba F; Koganei M; Kondo J
    Nucleic Acids Res; 2017 Dec; 45(21):12529-12535. PubMed ID: 29036479
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm.
    Savic M; Ilic-Tomic T; Macmaster R; Vasiljevic B; Conn GL
    J Bacteriol; 2008 Sep; 190(17):5855-61. PubMed ID: 18586937
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a missing sequence and functionally important residues of 16S rRNA:m(1)A1408 methyltransferase KamB that causes bacterial resistance to aminoglycoside antibiotics.
    Koscinski L; Feder M; Bujnicki JM
    Cell Cycle; 2007 May; 6(10):1268-71. PubMed ID: 17495534
    [No Abstract]   [Full Text] [Related]  

  • 20. Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
    Husain N; Tkaczuk KL; Tulsidas SR; Kaminska KH; Cubrilo S; Maravić-Vlahovicek G; Bujnicki JM; Sivaraman J
    Nucleic Acids Res; 2010 Jul; 38(12):4120-32. PubMed ID: 20194115
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.