BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 24968349)

  • 1. Mutations in the control of virulence sensor gene from Streptococcus pyogenes after infection in mice lead to clonal bacterial variants with altered gene regulatory activity and virulence.
    Mayfield JA; Liang Z; Agrahari G; Lee SW; Donahue DL; Ploplis VA; Castellino FJ
    PLoS One; 2014; 9(6):e100698. PubMed ID: 24968349
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A natural inactivating mutation in the CovS component of the CovRS regulatory operon in a pattern D Streptococcal pyogenes strain influences virulence-associated genes.
    Liang Z; Zhang Y; Agrahari G; Chandrahas V; Glinton K; Donahue DL; Balsara RD; Ploplis VA; Castellino FJ
    J Biol Chem; 2013 Mar; 288(9):6561-73. PubMed ID: 23316057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Complement-mediated opsonization of invasive group A Streptococcus pyogenes strain AP53 is regulated by the bacterial two-component cluster of virulence responder/sensor (CovRS) system.
    Agrahari G; Liang Z; Mayfield JA; Balsara RD; Ploplis VA; Castellino FJ
    J Biol Chem; 2013 Sep; 288(38):27494-27504. PubMed ID: 23928307
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CovRS-Regulated Transcriptome Analysis of a Hypervirulent M23 Strain of Group A Streptococcus pyogenes Provides New Insights into Virulence Determinants.
    Bao YJ; Liang Z; Mayfield JA; Lee SW; Ploplis VA; Castellino FJ
    J Bacteriol; 2015 Oct; 197(19):3191-205. PubMed ID: 26216843
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes.
    Treviño J; Perez N; Ramirez-Peña E; Liu Z; Shelburne SA; Musser JM; Sumby P
    Infect Immun; 2009 Aug; 77(8):3141-9. PubMed ID: 19451242
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus.
    Horstmann N; Tran CN; Brumlow C; DebRoy S; Yao H; Nogueras Gonzalez G; Makthal N; Kumaraswami M; Shelburne SA
    PLoS Pathog; 2018 Oct; 14(10):e1007354. PubMed ID: 30379939
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Null Mutations of Group A Streptococcus Orphan Kinase RocA: Selection in Mouse Infection and Comparison with CovS Mutations in Alteration of In Vitro and In Vivo Protease SpeB Expression and Virulence.
    Feng W; Minor D; Liu M; Li J; Ishaq SL; Yeoman C; Lei B
    Infect Immun; 2017 Jan; 85(1):. PubMed ID: 27795364
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Streptococcal inhibitor of complement promotes innate immune resistance phenotypes of invasive M1T1 group A Streptococcus.
    Pence MA; Rooijakkers SH; Cogen AL; Cole JN; Hollands A; Gallo RL; Nizet V
    J Innate Immun; 2010; 2(6):587-95. PubMed ID: 20814187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A
    Chiang-Ni C; Chiou HJ; Tseng HC; Hsu CY; Chiu CH
    mSphere; 2020 May; 5(3):. PubMed ID: 32434842
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Novel CovS Variant Harbored by a Colonization Strain Reduces Streptococcus pyogenes Virulence.
    Plainvert C; Rosinski-Chupin I; Weckel A; Lambert C; Touak G; Sauvage E; Poyart C; Glaser P; Fouet A
    J Bacteriol; 2023 Apr; 205(4):e0003923. PubMed ID: 36920220
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus.
    Horstmann N; Sahasrabhojane P; Saldaña M; Ajami NJ; Flores AR; Sumby P; Liu CG; Yao H; Su X; Thompson E; Shelburne SA
    Infect Immun; 2015 Mar; 83(3):1068-77. PubMed ID: 25561708
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface.
    Galloway-Peña J; DebRoy S; Brumlow C; Li X; Tran TT; Horstmann N; Yao H; Chen K; Wang F; Pan BF; Hawke DH; Thompson EJ; Arias CA; Fowler VG; Bhatti MM; Kalia A; Flores AR; Shelburne SA
    PLoS One; 2018; 13(12):e0207897. PubMed ID: 30517150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Partial loss of CovS function in Streptococcus pyogenes causes severe invasive disease.
    Tatsuno I; Okada R; Zhang Y; Isaka M; Hasegawa T
    BMC Res Notes; 2013 Mar; 6():126. PubMed ID: 23537349
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes.
    Dalton TL; Scott JR
    J Bacteriol; 2004 Jun; 186(12):3928-37. PubMed ID: 15175307
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria.
    Kansal RG; Datta V; Aziz RK; Abdeltawab NF; Rowe S; Kotb M
    J Infect Dis; 2010 Mar; 201(6):855-65. PubMed ID: 20151844
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Bacterial Markers of Identification of Invasive CovR/CovS-Inactivated Group A
    Shi YA; Chen TC; Chen YW; Liu YS; Chen YM; Lai CH; Chiu CH; Chiang-Ni C
    Microbiol Spectr; 2022 Oct; 10(5):e0203322. PubMed ID: 36200903
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genomic Characterization of a Pattern D Streptococcus pyogenes emm53 Isolate Reveals a Genetic Rationale for Invasive Skin Tropicity.
    Bao YJ; Liang Z; Mayfield JA; Donahue DL; Carothers KE; Lee SW; Ploplis VA; Castellino FJ
    J Bacteriol; 2016 Jun; 198(12):1712-24. PubMed ID: 27044623
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acidic stress enhances CovR/S-dependent gene repression through activation of the covR/S promoter in emm1-type group A Streptococcus.
    Chiang-Ni C; Tseng HC; Hung CH; Chiu CH
    Int J Med Microbiol; 2017 Sep; 307(6):329-339. PubMed ID: 28648357
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hyperphosphorylation of the Group A Streptococcal Control of Virulence Regulator Increases Promoter Occupancy Specifically at Virulence Factor-Encoding Genes.
    Horstmann N; Tran CN; Flores AR; Shelburne SA
    J Bacteriol; 2023 Jun; 205(6):e0011823. PubMed ID: 37289078
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single Amino Acid Replacements in RocA Disrupt Protein-Protein Interactions To Alter the Molecular Pathogenesis of Group A
    Bernard PE; Duarte A; Bogdanov M; Musser JM; Olsen RJ
    Infect Immun; 2020 Oct; 88(11):. PubMed ID: 32817331
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.