BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 24970265)

  • 1. Suppression of choroidal neovascularization through inhibition of APE1/Ref-1 redox activity.
    Li Y; Liu X; Zhou T; Kelley MR; Edwards PA; Gao H; Qiao X
    Invest Ophthalmol Vis Sci; 2014 Jun; 55(7):4461-9. PubMed ID: 24970265
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization.
    Li Y; Liu X; Zhou T; Kelley MR; Edwards P; Gao H; Qiao X
    Redox Biol; 2014; 2():485-94. PubMed ID: 24624338
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.
    Fishel ML; Jiang Y; Rajeshkumar NV; Scandura G; Sinn AL; He Y; Shen C; Jones DR; Pollok KE; Ivan M; Maitra A; Kelley MR
    Mol Cancer Ther; 2011 Sep; 10(9):1698-708. PubMed ID: 21700832
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.
    Kelley MR; Luo M; Reed A; Su D; Delaplane S; Borch RF; Nyland RL; Gross ML; Georgiadis MM
    Antioxid Redox Signal; 2011 Apr; 14(8):1387-401. PubMed ID: 20874257
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of APE1/Ref-1 redox activity with APX3330 blocks retinal angiogenesis in vitro and in vivo.
    Jiang A; Gao H; Kelley MR; Qiao X
    Vision Res; 2011 Jan; 51(1):93-100. PubMed ID: 20937296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration.
    Zou GM; Maitra A
    Mol Cancer Ther; 2008 Jul; 7(7):2012-21. PubMed ID: 18645011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival.
    Cardoso AA; Jiang Y; Luo M; Reed AM; Shahda S; He Y; Maitra A; Kelley MR; Fishel ML
    PLoS One; 2012; 7(10):e47462. PubMed ID: 23094050
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-mediated T Helper Cell Type 1 Responses.
    Akhter N; Takeda Y; Nara H; Araki A; Ishii N; Asao N; Asao H
    J Biol Chem; 2016 Nov; 291(45):23672-23680. PubMed ID: 27637330
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization.
    Sardar Pasha SPB; Sishtla K; Sulaiman RS; Park B; Shetty T; Shah F; Fishel ML; Wikel JH; Kelley MR; Corson TW
    J Pharmacol Exp Ther; 2018 Oct; 367(1):108-118. PubMed ID: 30076264
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of the redox function of APE1/Ref-1 in myeloid leukemia cell lines results in a hypersensitive response to retinoic acid-induced differentiation and apoptosis.
    Fishel ML; Colvin ES; Luo M; Kelley MR; Robertson KA
    Exp Hematol; 2010 Dec; 38(12):1178-88. PubMed ID: 20826193
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell lines.
    Cesaratto L; Codarin E; Vascotto C; Leonardi A; Kelley MR; Tiribelli C; Tell G
    PLoS One; 2013; 8(8):e70909. PubMed ID: 23967134
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1.
    Manvilla BA; Wauchope O; Seley-Radtke KL; Drohat AC
    Biochemistry; 2011 Dec; 50(48):10540-9. PubMed ID: 22032234
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer.
    Singh-Gupta V; Joiner MC; Runyan L; Yunker CK; Sarkar FH; Miller S; Gadgeel SM; Konski AA; Hillman GG
    J Thorac Oncol; 2011 Apr; 6(4):688-98. PubMed ID: 21325978
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of miR-146a-5p Inhibits Choroidal Neovascularization via the NF-κB Signaling Pathway by Targeting OTUD7B.
    Li L; Lai K; Gong Y; Huang C; Xu F; Li Y; Jin C
    Curr Eye Res; 2020 Dec; 45(12):1514-1525. PubMed ID: 32438838
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of APE1/Ref-1 for Neovascular Eye Diseases: From Biology to Therapy.
    Hartman GD; Lambert-Cheatham NA; Kelley MR; Corson TW
    Int J Mol Sci; 2021 Sep; 22(19):. PubMed ID: 34638620
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exposure of Barrett's and esophageal adenocarcinoma cells to bile acids activates EGFR-STAT3 signaling axis via induction of APE1.
    Bhat AA; Lu H; Soutto M; Capobianco A; Rai P; Zaika A; El-Rifai W
    Oncogene; 2018 Nov; 37(46):6011-6024. PubMed ID: 29991802
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor Activity and Mechanistic Characterization of APE1/Ref-1 Inhibitors in Bladder Cancer.
    Fishel ML; Xia H; McGeown J; McIlwain DW; Elbanna M; Craft AA; Kaimakliotis HZ; Sandusky GE; Zhang C; Pili R; Kelley MR; Jerde TJ
    Mol Cancer Ther; 2019 Nov; 18(11):1947-1960. PubMed ID: 31413178
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1.
    Luo M; Delaplane S; Jiang A; Reed A; He Y; Fishel M; Nyland RL; Borch RF; Qiao X; Georgiadis MM; Kelley MR
    Antioxid Redox Signal; 2008 Nov; 10(11):1853-67. PubMed ID: 18627350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
    Izumi-Nagai K; Nagai N; Ohgami K; Satofuka S; Ozawa Y; Tsubota K; Ohno S; Oike Y; Ishida S
    Invest Ophthalmol Vis Sci; 2008 Apr; 49(4):1679-85. PubMed ID: 18385091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel.
    Guerreiro PS; Corvacho E; Costa JG; Saraiva N; Fernandes AS; Castro M; Miranda JP; Oliveira NG
    Chem Biol Drug Des; 2017 Oct; 90(4):561-571. PubMed ID: 28303665
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.