658 related articles for article (PubMed ID: 24972680)
1. Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.
Pankiewicz JE; Guridi M; Kim J; Asuni AA; Sanchez S; Sullivan PM; Holtzman DM; Sadowski MJ
Acta Neuropathol Commun; 2014 Jun; 2():75. PubMed ID: 24972680
[TBL] [Abstract][Full Text] [Related]
2. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
[TBL] [Abstract][Full Text] [Related]
3. Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.
Hashimoto T; Serrano-Pozo A; Hori Y; Adams KW; Takeda S; Banerji AO; Mitani A; Joyner D; Thyssen DH; Bacskai BJ; Frosch MP; Spires-Jones TL; Finn MB; Holtzman DM; Hyman BT
J Neurosci; 2012 Oct; 32(43):15181-92. PubMed ID: 23100439
[TBL] [Abstract][Full Text] [Related]
4. Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice.
Fitz NF; Wolfe CM; Playso BE; Biedrzycki RJ; Lu Y; Nam KN; Lefterov I; Koldamova R
Mol Neurodegener; 2020 Jul; 15(1):41. PubMed ID: 32703241
[TBL] [Abstract][Full Text] [Related]
5. Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice.
Xu F; Vitek MP; Colton CA; Previti ML; Davis J; Van Nostrand WE
J Alzheimers Dis; 2012; 31(2):359-69. PubMed ID: 22635103
[TBL] [Abstract][Full Text] [Related]
6. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex.
Arold S; Sullivan P; Bilousova T; Teng E; Miller CA; Poon WW; Vinters HV; Cornwell LB; Saing T; Cole GM; Gylys KH
Acta Neuropathol; 2012 Jan; 123(1):39-52. PubMed ID: 22020632
[TBL] [Abstract][Full Text] [Related]
7. A flow cytometry-based
Kara E; Marks JD; Roe AD; Commins C; Fan Z; Calvo-Rodriguez M; Wegmann S; Hudry E; Hyman BT
J Biol Chem; 2018 Aug; 293(34):13247-13256. PubMed ID: 29950521
[TBL] [Abstract][Full Text] [Related]
8. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
[TBL] [Abstract][Full Text] [Related]
9. Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer's mice.
Sawmiller D; Koyama N; Fujiwara M; Segawa T; Maeda M; Mori T
J Biol Chem; 2023 Jul; 299(7):104846. PubMed ID: 37211092
[TBL] [Abstract][Full Text] [Related]
10. Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Castellano JM; Kim J; Stewart FR; Jiang H; DeMattos RB; Patterson BW; Fagan AM; Morris JC; Mawuenyega KG; Cruchaga C; Goate AM; Bales KR; Paul SM; Bateman RJ; Holtzman DM
Sci Transl Med; 2011 Jun; 3(89):89ra57. PubMed ID: 21715678
[TBL] [Abstract][Full Text] [Related]
11. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
Fitz NF; Cronican AA; Saleem M; Fauq AH; Chapman R; Lefterov I; Koldamova R
J Neurosci; 2012 Sep; 32(38):13125-36. PubMed ID: 22993429
[TBL] [Abstract][Full Text] [Related]
12. Association Between Apolipoprotein E ε2 vs ε4, Age, and β-Amyloid in Adults Without Cognitive Impairment.
Insel PS; Hansson O; Mattsson-Carlgren N
JAMA Neurol; 2021 Feb; 78(2):229-235. PubMed ID: 33044487
[TBL] [Abstract][Full Text] [Related]
13. Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
Zhao L; Gottesdiener AJ; Parmar M; Li M; Kaminsky SM; Chiuchiolo MJ; Sondhi D; Sullivan PM; Holtzman DM; Crystal RG; Paul SM
Neurobiol Aging; 2016 Aug; 44():159-172. PubMed ID: 27318144
[TBL] [Abstract][Full Text] [Related]
14. APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice.
Pankiewicz JE; Baquero-Buitrago J; Sanchez S; Lopez-Contreras J; Kim J; Sullivan PM; Holtzman DM; Sadowski MJ
Mol Neurodegener; 2017 Jan; 12(1):12. PubMed ID: 28143566
[TBL] [Abstract][Full Text] [Related]
15. Temporal Characterization of the Amyloidogenic APPswe/PS1dE9;hAPOE4 Mouse Model of Alzheimer's Disease.
Grenon MB; Papavergi MT; Bathini P; Sadowski M; Lemere CA
Int J Mol Sci; 2024 May; 25(11):. PubMed ID: 38891941
[TBL] [Abstract][Full Text] [Related]
16. Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models.
Liao F; Zhang TJ; Jiang H; Lefton KB; Robinson GO; Vassar R; Sullivan PM; Holtzman DM
Acta Neuropathol Commun; 2015 Nov; 3():70. PubMed ID: 26556230
[TBL] [Abstract][Full Text] [Related]
17. A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice.
Sadowski M; Pankiewicz J; Scholtzova H; Ripellino JA; Li Y; Schmidt SD; Mathews PM; Fryer JD; Holtzman DM; Sigurdsson EM; Wisniewski T
Am J Pathol; 2004 Sep; 165(3):937-48. PubMed ID: 15331417
[TBL] [Abstract][Full Text] [Related]
18. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
[TBL] [Abstract][Full Text] [Related]
19. APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease.
Jackson RJ; Keiser MS; Meltzer JC; Fykstra DP; Dierksmeier SE; Hajizadeh S; Kreuzer J; Morris R; Melloni A; Nakajima T; Tecedor L; Ranum PT; Carrell E; Chen Y; Nishtar MA; Holtzman DM; Haas W; Davidson BL; Hyman BT
Mol Ther; 2024 May; 32(5):1373-1386. PubMed ID: 38504517
[TBL] [Abstract][Full Text] [Related]
20. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]