BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

676 related articles for article (PubMed ID: 24975846)

  • 1. Phosphorylation dynamics of eukaryotic initiation factor 4E binding protein 1 (4E-BP1) is discordant with its potential to interact with eukaryotic initiation factor 4E (eIF4E).
    Showkat M; Beigh MA; Bhat BB; Batool A; Andrabi KI
    Cell Signal; 2014 Oct; 26(10):2117-21. PubMed ID: 24975846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin.
    Batool A; Majeed ST; Aashaq S; Majeed R; Shah G; Nazir N; Andrabi KI
    Int J Biol Macromol; 2019 Mar; 125():651-659. PubMed ID: 30552925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
    Wang X; Beugnet A; Murakami M; Yamanaka S; Proud CG
    Mol Cell Biol; 2005 Apr; 25(7):2558-72. PubMed ID: 15767663
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Different roles for the TOS and RAIP motifs of the translational regulator protein 4E-BP1 in the association with raptor and phosphorylation by mTOR in the regulation of cell size.
    Eguchi S; Tokunaga C; Hidayat S; Oshiro N; Yoshino K; Kikkawa U; Yonezawa K
    Genes Cells; 2006 Jul; 11(7):757-66. PubMed ID: 16824195
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
    Schalm SS; Fingar DC; Sabatini DM; Blenis J
    Curr Biol; 2003 May; 13(10):797-806. PubMed ID: 12747827
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.
    Liu L; Li F; Cardelli JA; Martin KA; Blenis J; Huang S
    Oncogene; 2006 Nov; 25(53):7029-40. PubMed ID: 16715128
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway.
    Nathan CO; Amirghahari N; Abreo F; Rong X; Caldito G; Jones ML; Zhou H; Smith M; Kimberly D; Glass J
    Clin Cancer Res; 2004 Sep; 10(17):5820-7. PubMed ID: 15355912
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1.
    Beugnet A; Wang X; Proud CG
    J Biol Chem; 2003 Oct; 278(42):40717-22. PubMed ID: 12912989
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.
    El-Chaâr D; Gagnon A; Sorisky A
    Int J Obes Relat Metab Disord; 2004 Feb; 28(2):191-8. PubMed ID: 14970836
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Eukaryotic initiation factor 4E is a novel effector of mTORC1 signaling pathway in cross talk with Mnk1.
    Batool A; Majeed ST; Aashaq S; Majeed R; Bhat NN; Andrabi KI
    Mol Cell Biochem; 2020 Feb; 465(1-2):13-26. PubMed ID: 31782083
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1.
    Tee AR; Tee JA; Blenis J
    FEBS Lett; 2004 Apr; 564(1-2):58-62. PubMed ID: 15094042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
    Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
    Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
    [TBL] [Abstract][Full Text] [Related]  

  • 13. mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E.
    Fingar DC; Richardson CJ; Tee AR; Cheatham L; Tsou C; Blenis J
    Mol Cell Biol; 2004 Jan; 24(1):200-16. PubMed ID: 14673156
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.
    Villalonga P; Fernández de Mattos S; Ridley AJ
    J Biol Chem; 2009 Dec; 284(51):35287-96. PubMed ID: 19850923
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E).
    Sun R; Cheng E; Velásquez C; Chang Y; Moore PS
    J Biol Chem; 2019 Aug; 294(31):11840-11852. PubMed ID: 31201269
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle.
    Lang CH; Frost RA
    J Cell Physiol; 2005 Apr; 203(1):144-55. PubMed ID: 15389631
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a conserved motif required for mTOR signaling.
    Schalm SS; Blenis J
    Curr Biol; 2002 Apr; 12(8):632-9. PubMed ID: 11967149
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.
    Gingras AC; Gygi SP; Raught B; Polakiewicz RD; Abraham RT; Hoekstra MF; Aebersold R; Sonenberg N
    Genes Dev; 1999 Jun; 13(11):1422-37. PubMed ID: 10364159
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif.
    Nojima H; Tokunaga C; Eguchi S; Oshiro N; Hidayat S; Yoshino K; Hara K; Tanaka N; Avruch J; Yonezawa K
    J Biol Chem; 2003 May; 278(18):15461-4. PubMed ID: 12604610
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1.
    Böhm R; Imseng S; Jakob RP; Hall MN; Maier T; Hiller S
    Mol Cell; 2021 Jun; 81(11):2403-2416.e5. PubMed ID: 33852892
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.