BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 2497730)

  • 1. Glucagon desensitization of adenylate cyclase and stimulation of inositol phospholipid metabolism does not involve the inhibitory guanine nucleotide regulatory protein Gi, which is inactivated upon challenge of hepatocytes with glucagon.
    Murphy GJ; Gawler DJ; Milligan G; Wakelam MJ; Pyne NJ; Houslay MD
    Biochem J; 1989 Apr; 259(1):191-7. PubMed ID: 2497730
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
    Houslay MD; Gawler DJ; Milligan G; Wilson A
    Cell Signal; 1989; 1(1):9-22. PubMed ID: 2561940
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The rapid desensitization of glucagon-stimulated adenylate cyclase is a cyclic AMP-independent process that can be mimicked by hormones which stimulate inositol phospholipid metabolism.
    Murphy GJ; Hruby VJ; Trivedi D; Wakelam MJ; Houslay MD
    Biochem J; 1987 Apr; 243(1):39-46. PubMed ID: 3038085
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determination of G-protein levels, ADP-ribosylation by cholera and pertussis toxins and the regulation of adenylyl cyclase activity in liver plasma membranes from lean and genetically diabetic (db/db) mice.
    Palmer TM; Houslay MD
    Biochim Biophys Acta; 1991 Oct; 1097(3):193-204. PubMed ID: 1932144
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pertussis toxin or phorbol 12-myristate 13-acetate can distinguish between epidermal growth factor- and angiotensin-stimulated signals in hepatocytes.
    Johnson RM; Connelly PA; Sisk RB; Pobiner BF; Hewlett EL; Garrison JC
    Proc Natl Acad Sci U S A; 1986 Apr; 83(7):2032-6. PubMed ID: 3083411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Treatment of intact hepatocytes with either the phorbol ester TPA or glucagon elicits the phosphorylation and functional inactivation of the inhibitory guanine nucleotide regulatory protein Gi.
    Pyne NJ; Murphy GJ; Milligan G; Houslay MD
    FEBS Lett; 1989 Jan; 243(1):77-82. PubMed ID: 2493392
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
    Hernández-Sotomayor SM; Macías-Silva M; Plebañski M; García-Sáinz JA
    Biochim Biophys Acta; 1988 Dec; 972(3):311-9. PubMed ID: 2848590
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase C stimulates adenylate cyclase activity in prolactin-secreting rat adenoma (GH4C1) pituicytes by inactivating the inhibitory GTP-binding protein Gi.
    Gordeladze JO; Björo T; Torjesen PA; Ostberg BC; Haug E; Gautvik KM
    Eur J Biochem; 1989 Aug; 183(2):397-406. PubMed ID: 2569396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Diabetes-induced alterations in the expression, functioning and phosphorylation state of the inhibitory guanine nucleotide regulatory protein Gi-2 in hepatocytes.
    Bushfield M; Griffiths SL; Murphy GJ; Pyne NJ; Knowler JT; Milligan G; Parker PJ; Mollner S; Houslay MD
    Biochem J; 1990 Oct; 271(2):365-72. PubMed ID: 1700700
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
    Lynch CJ; Blackmore PF; Johnson EH; Wange RL; Krone PK; Exton JH
    J Clin Invest; 1989 Jun; 83(6):2050-62. PubMed ID: 2498395
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Treatment of streptozotocin-diabetic rats with metformin restores the ability of insulin to inhibit adenylate cyclase activity and demonstrates that insulin does not exert this action through the inhibitory guanine nucleotide regulatory protein Gi.
    Gawler D; Milligan G; Houslay MD
    Biochem J; 1988 Jan; 249(2):537-42. PubMed ID: 3124829
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Islet-activating protein blocks glucagon desensitization in intact hepatocytes.
    Heyworth CM; Hanski E; Houslay MD
    Biochem J; 1984 Aug; 222(1):189-94. PubMed ID: 6089757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. G-proteins of fat-cells. Role in hormonal regulation of intracellular inositol 1,4,5-trisphosphate.
    Rapiejko PJ; Northup JK; Evans T; Brown JE; Malbon CC
    Biochem J; 1986 Nov; 240(1):35-40. PubMed ID: 3103610
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of Ni in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes.
    Pobiner BF; Hewlett EL; Garrison JC
    J Biol Chem; 1985 Dec; 260(30):16200-9. PubMed ID: 2999149
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fluoroaluminates mimic muscarinic- and oxytocin-receptor-mediated generation of inositol phosphates and contraction in the intact guinea-pig myometrium. Role for a pertussis/cholera-toxin-insensitive G protein.
    Marc S; Leiber D; Harbon S
    Biochem J; 1988 Oct; 255(2):705-13. PubMed ID: 2849425
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitory GTP-binding regulatory protein Gi3 can couple angiotensin II receptors to inhibition of adenylyl cyclase in hepatocytes.
    Pobiner BF; Northup JK; Bauer PH; Fraser ED; Garrison JC
    Mol Pharmacol; 1991 Aug; 40(2):156-67. PubMed ID: 1908548
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein kinase C activation mimics but does not mediate thyrotropin-induced desensitization of adenylyl cyclase in cultured dog thyroid cells.
    Deery WJ; Rani CS
    Endocrinology; 1991 Jun; 128(6):2967-75. PubMed ID: 1903697
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Demonstration of inhibitory guanine nucleotide regulatory protein (Gi) function in liver and hepatocyte membranes from streptozotocin-treated rats.
    Kirkham DM; Murphy GJ; Young P
    Biochem J; 1992 Jun; 284 ( Pt 2)(Pt 2):301-4. PubMed ID: 1534652
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells.
    Cruciani RA; Dvorkin B; Morris SA; Crain SM; Makman MH
    Proc Natl Acad Sci U S A; 1993 Apr; 90(7):3019-23. PubMed ID: 8385355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Changes in the phosphorylation state of the inhibitory guanine-nucleotide-binding protein Gi-2 in hepatocytes from lean (Fa/Fa) and obese (fa/fa) Zucker rats.
    Bushfield M; Pyne NJ; Houslay MD
    Eur J Biochem; 1990 Sep; 192(2):537-42. PubMed ID: 2120055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.