176 related articles for article (PubMed ID: 24977713)
1. Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2.
Oliveira JM; Rebuffat SA; Gasa R; Gomis R
Can J Physiol Pharmacol; 2014 Aug; 92(8):613-20. PubMed ID: 24977713
[TBL] [Abstract][Full Text] [Related]
2. Tungstate promotes β-cell survival in Irs2-/- mice.
Oliveira JM; Rebuffat SA; Gasa R; Burks DJ; Garcia A; Kalko SG; Zafra D; Guinovart JJ; Gomis R
Am J Physiol Endocrinol Metab; 2014 Jan; 306(1):E36-47. PubMed ID: 24253047
[TBL] [Abstract][Full Text] [Related]
3. Pdx1 restores beta cell function in Irs2 knockout mice.
Kushner JA; Ye J; Schubert M; Burks DJ; Dow MA; Flint CL; Dutta S; Wright CV; Montminy MR; White MF
J Clin Invest; 2002 May; 109(9):1193-201. PubMed ID: 11994408
[TBL] [Abstract][Full Text] [Related]
4. Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice.
Arroba AI; Revuelta-Cervantes J; Menes L; González-Rodríguez Á; Pardo V; de la Villa P; Burks DJ; Valverde ÁM
Invest Ophthalmol Vis Sci; 2013 Jun; 54(6):4215-25. PubMed ID: 23702782
[TBL] [Abstract][Full Text] [Related]
5. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.
Hennige AM; Burks DJ; Ozcan U; Kulkarni RN; Ye J; Park S; Schubert M; Fisher TL; Dow MA; Leshan R; Zakaria M; Mossa-Basha M; White MF
J Clin Invest; 2003 Nov; 112(10):1521-32. PubMed ID: 14617753
[TBL] [Abstract][Full Text] [Related]
6. Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells.
Kawada Y; Asahara SI; Sugiura Y; Sato A; Furubayashi A; Kawamura M; Bartolome A; Terashi-Suzuki E; Takai T; Kanno A; Koyanagi-Kimura M; Matsuda T; Hashimoto N; Kido Y
PLoS One; 2017; 12(9):e0184435. PubMed ID: 28886131
[TBL] [Abstract][Full Text] [Related]
7. Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.
Kubota N; Terauchi Y; Tobe K; Yano W; Suzuki R; Ueki K; Takamoto I; Satoh H; Maki T; Kubota T; Moroi M; Okada-Iwabu M; Ezaki O; Nagai R; Ueta Y; Kadowaki T; Noda T
J Clin Invest; 2004 Oct; 114(7):917-27. PubMed ID: 15467830
[TBL] [Abstract][Full Text] [Related]
8. PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin.
Besse-Patin A; Jeromson S; Levesque-Damphousse P; Secco B; Laplante M; Estall JL
Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4285-4290. PubMed ID: 30770439
[TBL] [Abstract][Full Text] [Related]
9. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
Withers DJ; Burks DJ; Towery HH; Altamuro SL; Flint CL; White MF
Nat Genet; 1999 Sep; 23(1):32-40. PubMed ID: 10471495
[TBL] [Abstract][Full Text] [Related]
10. Wnt3a regulates proliferation, apoptosis and function of pancreatic NIT-1 beta cells via activation of IRS2/PI3K signaling.
Gui S; Yuan G; Wang L; Zhou L; Xue Y; Yu Y; Zhang J; Zhang M; Yang Y; Wang DW
J Cell Biochem; 2013 Jul; 114(7):1488-97. PubMed ID: 23296977
[TBL] [Abstract][Full Text] [Related]
11. Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J:Jcl mice deficient in insulin receptor substrate 2.
Hashimoto H; Arai T; Takeguchi A; Hioki K; Ohnishi Y; Kawai K; Ito M; Suzuki R; Yamauchi T; Ohsugi M; Saito M; Ueyama Y; Tobe K; Kadowaki T; Tamaoki N; Kosaka K
Comp Med; 2006 Jun; 56(3):176-87. PubMed ID: 16774126
[TBL] [Abstract][Full Text] [Related]
12. Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/- mice.
Burgos-Ramos E; González-Rodríguez A; Canelles S; Baquedano E; Frago LM; Revuelta-Cervantes J; Gómez-Ambrosi J; Frühbeck G; Chowen JA; Argente J; Valverde AM; Barrios V
Endocrinology; 2012 Mar; 153(3):1129-40. PubMed ID: 22210743
[TBL] [Abstract][Full Text] [Related]
13. Molecular mechanisms of atherosclerosis in metabolic syndrome: role of reduced IRS2-dependent signaling.
González-Navarro H; Vinué A; Vila-Caballer M; Fortuño A; Beloqui O; Zalba G; Burks D; Díez J; Andrés V
Arterioscler Thromb Vasc Biol; 2008 Dec; 28(12):2187-94. PubMed ID: 18802016
[TBL] [Abstract][Full Text] [Related]
14. Exercise improves glucose homeostasis that has been impaired by a high-fat diet by potentiating pancreatic beta-cell function and mass through IRS2 in diabetic rats.
Park S; Hong SM; Lee JE; Sung SR
J Appl Physiol (1985); 2007 Nov; 103(5):1764-71. PubMed ID: 17761790
[TBL] [Abstract][Full Text] [Related]
15. Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
Stamateris RE; Sharma RB; Kong Y; Ebrahimpour P; Panday D; Ranganath P; Zou B; Levitt H; Parambil NA; O'Donnell CP; García-Ocaña A; Alonso LC
Diabetes; 2016 Apr; 65(4):981-95. PubMed ID: 26740601
[TBL] [Abstract][Full Text] [Related]
16. Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.
Park S; Dong X; Fisher TL; Dunn S; Omer AK; Weir G; White MF
J Biol Chem; 2006 Jan; 281(2):1159-68. PubMed ID: 16272563
[TBL] [Abstract][Full Text] [Related]
17. Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.
Lin X; Taguchi A; Park S; Kushner JA; Li F; Li Y; White MF
J Clin Invest; 2004 Oct; 114(7):908-16. PubMed ID: 15467829
[TBL] [Abstract][Full Text] [Related]
18. Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.
Xuan S; Szabolcs M; Cinti F; Perincheri S; Accili D; Efstratiadis A
J Biol Chem; 2010 Dec; 285(52):41044-50. PubMed ID: 20947509
[TBL] [Abstract][Full Text] [Related]
19. Prolonged Elimination of Negative Feedback Control Mechanisms Along the Insulin Signaling Pathway Impairs β-Cell Function In Vivo.
Isaac R; Vinik Y; Boura-Halfon S; Farack L; Streim S; Elhanany E; Kam Z; Zick Y
Diabetes; 2017 Jul; 66(7):1879-1889. PubMed ID: 28424159
[TBL] [Abstract][Full Text] [Related]
20. Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.
Takamoto I; Terauchi Y; Kubota N; Ohsugi M; Ueki K; Kadowaki T
Diabetes Obes Metab; 2008 Nov; 10 Suppl 4():147-56. PubMed ID: 18834442
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]