These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 24977713)

  • 1. Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2.
    Oliveira JM; Rebuffat SA; Gasa R; Gomis R
    Can J Physiol Pharmacol; 2014 Aug; 92(8):613-20. PubMed ID: 24977713
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tungstate promotes β-cell survival in Irs2-/- mice.
    Oliveira JM; Rebuffat SA; Gasa R; Burks DJ; Garcia A; Kalko SG; Zafra D; Guinovart JJ; Gomis R
    Am J Physiol Endocrinol Metab; 2014 Jan; 306(1):E36-47. PubMed ID: 24253047
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pdx1 restores beta cell function in Irs2 knockout mice.
    Kushner JA; Ye J; Schubert M; Burks DJ; Dow MA; Flint CL; Dutta S; Wright CV; Montminy MR; White MF
    J Clin Invest; 2002 May; 109(9):1193-201. PubMed ID: 11994408
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice.
    Arroba AI; Revuelta-Cervantes J; Menes L; González-Rodríguez Á; Pardo V; de la Villa P; Burks DJ; Valverde ÁM
    Invest Ophthalmol Vis Sci; 2013 Jun; 54(6):4215-25. PubMed ID: 23702782
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.
    Hennige AM; Burks DJ; Ozcan U; Kulkarni RN; Ye J; Park S; Schubert M; Fisher TL; Dow MA; Leshan R; Zakaria M; Mossa-Basha M; White MF
    J Clin Invest; 2003 Nov; 112(10):1521-32. PubMed ID: 14617753
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells.
    Kawada Y; Asahara SI; Sugiura Y; Sato A; Furubayashi A; Kawamura M; Bartolome A; Terashi-Suzuki E; Takai T; Kanno A; Koyanagi-Kimura M; Matsuda T; Hashimoto N; Kido Y
    PLoS One; 2017; 12(9):e0184435. PubMed ID: 28886131
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.
    Kubota N; Terauchi Y; Tobe K; Yano W; Suzuki R; Ueki K; Takamoto I; Satoh H; Maki T; Kubota T; Moroi M; Okada-Iwabu M; Ezaki O; Nagai R; Ueta Y; Kadowaki T; Noda T
    J Clin Invest; 2004 Oct; 114(7):917-27. PubMed ID: 15467830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin.
    Besse-Patin A; Jeromson S; Levesque-Damphousse P; Secco B; Laplante M; Estall JL
    Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4285-4290. PubMed ID: 30770439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
    Withers DJ; Burks DJ; Towery HH; Altamuro SL; Flint CL; White MF
    Nat Genet; 1999 Sep; 23(1):32-40. PubMed ID: 10471495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Wnt3a regulates proliferation, apoptosis and function of pancreatic NIT-1 beta cells via activation of IRS2/PI3K signaling.
    Gui S; Yuan G; Wang L; Zhou L; Xue Y; Yu Y; Zhang J; Zhang M; Yang Y; Wang DW
    J Cell Biochem; 2013 Jul; 114(7):1488-97. PubMed ID: 23296977
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J:Jcl mice deficient in insulin receptor substrate 2.
    Hashimoto H; Arai T; Takeguchi A; Hioki K; Ohnishi Y; Kawai K; Ito M; Suzuki R; Yamauchi T; Ohsugi M; Saito M; Ueyama Y; Tobe K; Kadowaki T; Tamaoki N; Kosaka K
    Comp Med; 2006 Jun; 56(3):176-87. PubMed ID: 16774126
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/- mice.
    Burgos-Ramos E; González-Rodríguez A; Canelles S; Baquedano E; Frago LM; Revuelta-Cervantes J; Gómez-Ambrosi J; Frühbeck G; Chowen JA; Argente J; Valverde AM; Barrios V
    Endocrinology; 2012 Mar; 153(3):1129-40. PubMed ID: 22210743
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular mechanisms of atherosclerosis in metabolic syndrome: role of reduced IRS2-dependent signaling.
    González-Navarro H; Vinué A; Vila-Caballer M; Fortuño A; Beloqui O; Zalba G; Burks D; Díez J; Andrés V
    Arterioscler Thromb Vasc Biol; 2008 Dec; 28(12):2187-94. PubMed ID: 18802016
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exercise improves glucose homeostasis that has been impaired by a high-fat diet by potentiating pancreatic beta-cell function and mass through IRS2 in diabetic rats.
    Park S; Hong SM; Lee JE; Sung SR
    J Appl Physiol (1985); 2007 Nov; 103(5):1764-71. PubMed ID: 17761790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
    Stamateris RE; Sharma RB; Kong Y; Ebrahimpour P; Panday D; Ranganath P; Zou B; Levitt H; Parambil NA; O'Donnell CP; García-Ocaña A; Alonso LC
    Diabetes; 2016 Apr; 65(4):981-95. PubMed ID: 26740601
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.
    Park S; Dong X; Fisher TL; Dunn S; Omer AK; Weir G; White MF
    J Biol Chem; 2006 Jan; 281(2):1159-68. PubMed ID: 16272563
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.
    Lin X; Taguchi A; Park S; Kushner JA; Li F; Li Y; White MF
    J Clin Invest; 2004 Oct; 114(7):908-16. PubMed ID: 15467829
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.
    Xuan S; Szabolcs M; Cinti F; Perincheri S; Accili D; Efstratiadis A
    J Biol Chem; 2010 Dec; 285(52):41044-50. PubMed ID: 20947509
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prolonged Elimination of Negative Feedback Control Mechanisms Along the Insulin Signaling Pathway Impairs β-Cell Function In Vivo.
    Isaac R; Vinik Y; Boura-Halfon S; Farack L; Streim S; Elhanany E; Kam Z; Zick Y
    Diabetes; 2017 Jul; 66(7):1879-1889. PubMed ID: 28424159
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.
    Takamoto I; Terauchi Y; Kubota N; Ohsugi M; Ueki K; Kadowaki T
    Diabetes Obes Metab; 2008 Nov; 10 Suppl 4():147-56. PubMed ID: 18834442
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.