189 related articles for article (PubMed ID: 24982353)
21. Elevation of cyclic AMP in Jurkat T-cells provokes distinct transcriptional responses through the protein kinase A (PKA) and exchange protein activated by cyclic AMP (EPAC) pathways.
Fuld S; Borland G; Yarwood SJ
Exp Cell Res; 2005 Sep; 309(1):161-73. PubMed ID: 15963501
[TBL] [Abstract][Full Text] [Related]
22. Prostaglandin E2 activates Rap1 via EP2/EP4 receptors and cAMP-signaling in rheumatoid synovial fibroblasts: involvement of Epac1 and PKA.
Kojima F; Kapoor M; Kawai S; Yang L; Aronoff DM; Crofford LJ
Prostaglandins Other Lipid Mediat; 2009 Jun; 89(1-2):26-33. PubMed ID: 19464664
[TBL] [Abstract][Full Text] [Related]
23. The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention.
Almahariq M; Mei FC; Cheng X
Acta Biochim Biophys Sin (Shanghai); 2016 Jan; 48(1):75-81. PubMed ID: 26525949
[TBL] [Abstract][Full Text] [Related]
24. CAMP activates Rap1 in differentiating mouse male germ cells: a new signaling pathway mediated by the cAMP-activated exchange factor Epac?
Berruti G
Cell Mol Biol (Noisy-le-grand); 2003 May; 49(3):381-8. PubMed ID: 12887090
[TBL] [Abstract][Full Text] [Related]
25. Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP.
Birukova AA; Burdette D; Moldobaeva N; Xing J; Fu P; Birukov KG
Microvasc Res; 2010 Mar; 79(2):128-38. PubMed ID: 19962392
[TBL] [Abstract][Full Text] [Related]
26. The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages.
Bryn T; Mahic M; Enserink JM; Schwede F; Aandahl EM; Taskén K
J Immunol; 2006 Jun; 176(12):7361-70. PubMed ID: 16751380
[TBL] [Abstract][Full Text] [Related]
27. Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment.
Kumar N; Prasad P; Jash E; Saini M; Husain A; Goldman A; Sehrawat S
Mol Cell Biochem; 2018 Oct; 447(1-2):77-92. PubMed ID: 29417338
[TBL] [Abstract][Full Text] [Related]
28. Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation.
Garg J; Feng YX; Jansen SR; Friedrich J; Lezoualc'h F; Schmidt M; Wieland T
Oncotarget; 2017 Jul; 8(27):44732-44748. PubMed ID: 28512254
[TBL] [Abstract][Full Text] [Related]
29. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP.
de Rooij J; Zwartkruis FJ; Verheijen MH; Cool RH; Nijman SM; Wittinghofer A; Bos JL
Nature; 1998 Dec; 396(6710):474-7. PubMed ID: 9853756
[TBL] [Abstract][Full Text] [Related]
30. Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.
Tiwari S; Felekkis K; Moon EY; Flies A; Sherr DH; Lerner A
Blood; 2004 Apr; 103(7):2661-7. PubMed ID: 14615375
[TBL] [Abstract][Full Text] [Related]
31. Prostaglandin D2-DP signaling promotes endothelial barrier function via the cAMP/PKA/Tiam1/Rac1 pathway.
Kobayashi K; Tsubosaka Y; Hori M; Narumiya S; Ozaki H; Murata T
Arterioscler Thromb Vasc Biol; 2013 Mar; 33(3):565-71. PubMed ID: 23307871
[TBL] [Abstract][Full Text] [Related]
32. The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity.
Zieba BJ; Artamonov MV; Jin L; Momotani K; Ho R; Franke AS; Neppl RL; Stevenson AS; Khromov AS; Chrzanowska-Wodnicka M; Somlyo AV
J Biol Chem; 2011 May; 286(19):16681-92. PubMed ID: 21454546
[TBL] [Abstract][Full Text] [Related]
33. Exchange protein directly activated by cAMP 1 (Epac1) is expressed in human neutrophils and mediates cAMP-dependent activation of the monomeric GTPase Rap1.
Dash-Koney M; Deevi RK; McFarlane C; Dib K
J Leukoc Biol; 2011 Oct; 90(4):741-9. PubMed ID: 21750123
[TBL] [Abstract][Full Text] [Related]
34. Cyclic AMP-dependent, protein kinase A-independent activation of extracellular signal-regulated kinase 1/2 following adenosine receptor stimulation in human umbilical vein endothelial cells: role of exchange protein activated by cAMP 1 (Epac1).
Fang Y; Olah ME
J Pharmacol Exp Ther; 2007 Sep; 322(3):1189-200. PubMed ID: 17565009
[TBL] [Abstract][Full Text] [Related]
35. Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha.
Maillet M; Robert SJ; Cacquevel M; Gastineau M; Vivien D; Bertoglio J; Zugaza JL; Fischmeister R; Lezoualc'h F
Nat Cell Biol; 2003 Jul; 5(7):633-9. PubMed ID: 12819788
[TBL] [Abstract][Full Text] [Related]
36. Laminin regulates mouse embryonic stem cell migration: involvement of Epac1/Rap1 and Rac1/cdc42.
Suh HN; Han HJ
Am J Physiol Cell Physiol; 2010 May; 298(5):C1159-69. PubMed ID: 20089929
[TBL] [Abstract][Full Text] [Related]
37. Epac1-Rap1 signaling regulates monocyte adhesion and chemotaxis.
Lorenowicz MJ; van Gils J; de Boer M; Hordijk PL; Fernandez-Borja M
J Leukoc Biol; 2006 Dec; 80(6):1542-52. PubMed ID: 16940330
[TBL] [Abstract][Full Text] [Related]
38. Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cells.
Goto A; Hoshino M; Matsuda M; Nakamura T
Mol Biol Cell; 2011 May; 22(10):1780-90. PubMed ID: 21460187
[TBL] [Abstract][Full Text] [Related]
39. The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages.
Misra UK; Kaczowka S; Pizzo SV
Cell Signal; 2008 Aug; 20(8):1459-70. PubMed ID: 18495429
[TBL] [Abstract][Full Text] [Related]
40. Understanding cAMP-dependent allostery by NMR spectroscopy: comparative analysis of the EPAC1 cAMP-binding domain in its apo and cAMP-bound states.
Mazhab-Jafari MT; Das R; Fotheringham SA; SilDas S; Chowdhury S; Melacini G
J Am Chem Soc; 2007 Nov; 129(46):14482-92. PubMed ID: 17973384
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]