BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 24994062)

  • 1. Repair of endogenous DNA base lesions modulate lifespan in mice.
    Meira LB; Calvo JA; Shah D; Klapacz J; Moroski-Erkul CA; Bronson RT; Samson LD
    DNA Repair (Amst); 2014 Sep; 21():78-86. PubMed ID: 24994062
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.
    Fahrer J; Frisch J; Nagel G; Kraus A; Dörsam B; Thomas AD; Reißig S; Waisman A; Kaina B
    Carcinogenesis; 2015 Oct; 36(10):1235-44. PubMed ID: 26243310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
    Agnihotri S; Gajadhar AS; Ternamian C; Gorlia T; Diefes KL; Mischel PS; Kelly J; McGown G; Thorncroft M; Carlson BL; Sarkaria JN; Margison GP; Aldape K; Hawkins C; Hegi M; Guha A
    J Clin Invest; 2012 Jan; 122(1):253-66. PubMed ID: 22156195
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
    Kaina B; Christmann M; Naumann S; Roos WP
    DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA alkylation lesion repair: outcomes and implications in cancer chemotherapy.
    Peng Y; Pei H
    J Zhejiang Univ Sci B; 2021 Jan; 22(1):47-62. PubMed ID: 33448187
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mismatch repair proteins play a role in ATR activation upon temozolomide treatment in MGMT-methylated glioblastoma.
    Ganesa S; Sule A; Sundaram RK; Bindra RS
    Sci Rep; 2022 Apr; 12(1):5827. PubMed ID: 35388070
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway.
    Chou WC; Hu LY; Hsiung CN; Shen CY
    Carcinogenesis; 2015 Aug; 36(8):832-40. PubMed ID: 26025911
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney.
    Ebrahimkhani MR; Daneshmand A; Mazumder A; Allocca M; Calvo JA; Abolhassani N; Jhun I; Muthupalani S; Ayata C; Samson LD
    Proc Natl Acad Sci U S A; 2014 Nov; 111(45):E4878-86. PubMed ID: 25349415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms.
    Kuo CY; Chou WC; Wu CC; Wong TS; Kakadiya R; Lee TC; Su TL; Wang HC
    Oncotarget; 2015 Sep; 6(28):25770-83. PubMed ID: 26208482
    [TBL] [Abstract][Full Text] [Related]  

  • 10. No-observed effect levels are associated with up-regulation of MGMT following MMS exposure.
    Doak SH; Brüsehafer K; Dudley E; Quick E; Johnson G; Newton RP; Jenkins GJ
    Mutat Res; 2008 Dec; 648(1-2):9-14. PubMed ID: 18992265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.
    Tang JB; Svilar D; Trivedi RN; Wang XH; Goellner EM; Moore B; Hamilton RL; Banze LA; Brown AR; Sobol RW
    Neuro Oncol; 2011 May; 13(5):471-86. PubMed ID: 21377995
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response.
    Milano L; Charlier CF; Andreguetti R; Cox T; Healing E; Thomé MP; Elliott RM; Samson LD; Masson JY; Lenz G; Henriques JAP; Nohturfft A; Meira LB
    Proc Natl Acad Sci U S A; 2022 Mar; 119(9):. PubMed ID: 35197283
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.
    Wirtz S; Nagel G; Eshkind L; Neurath MF; Samson LD; Kaina B
    Carcinogenesis; 2010 Dec; 31(12):2111-7. PubMed ID: 20732909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PARP1-MGMT complex underpins pathway crosstalk in O
    Cropper JD; Alimbetov DS; Brown KTG; Likhotvorik RI; Robles AJ; Guerra JT; He B; Chen Y; Kwon Y; Kurmasheva RT
    J Hematol Oncol; 2022 Oct; 15(1):146. PubMed ID: 36242092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.
    Bobola MS; Kolstoe DD; Blank A; Silber JR
    Mol Cancer Ther; 2010 May; 9(5):1208-18. PubMed ID: 20457618
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins.
    Bugni JM; Meira LB; Samson LD
    Oncogene; 2009 Feb; 28(5):734-41. PubMed ID: 19029948
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.
    Engelward BP; Weeda G; Wyatt MD; Broekhof JL; de Wit J; Donker I; Allan JM; Gold B; Hoeijmakers JH; Samson LD
    Proc Natl Acad Sci U S A; 1997 Nov; 94(24):13087-92. PubMed ID: 9371804
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice.
    Meira LB; Moroski-Erkul CA; Green SL; Calvo JA; Bronson RT; Shah D; Samson LD
    Proc Natl Acad Sci U S A; 2009 Jan; 106(3):888-93. PubMed ID: 19139400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.
    Dominick G; Bowman J; Li X; Miller RA; Garcia GG
    Aging Cell; 2017 Feb; 16(1):52-60. PubMed ID: 27618784
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA repair modulates the vulnerability of the developing brain to alkylating agents.
    Kisby GE; Olivas A; Park T; Churchwell M; Doerge D; Samson LD; Gerson SL; Turker MS
    DNA Repair (Amst); 2009 Mar; 8(3):400-12. PubMed ID: 19162564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.