These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

409 related articles for article (PubMed ID: 24994715)

  • 21. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma.
    Wei SF; He DH; Zhang SB; Lu Y; Ye X; Fan XZ; Wang H; Wang Q; Liu YQ
    Biochem Pharmacol; 2021 Aug; 190():114593. PubMed ID: 33964282
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.
    Infante P; Alfonsi R; Ingallina C; Quaglio D; Ghirga F; D'Acquarica I; Bernardi F; Di Magno L; Canettieri G; Screpanti I; Gulino A; Botta B; Mori M; Di Marcotullio L
    Cell Death Dis; 2016 Sep; 7(9):e2376. PubMed ID: 27899820
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.
    Rodriguez-Blanco J; Li B; Long J; Shen C; Yang F; Orton D; Collins S; Kasahara N; Ayad NG; McCrea HJ; Roussel MF; Weiss WA; Capobianco AJ; Robbins DJ
    Clin Cancer Res; 2019 Feb; 25(4):1379-1388. PubMed ID: 30487124
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.
    Huang L; Walter V; Hayes DN; Onaitis M
    Clin Cancer Res; 2014 Mar; 20(6):1566-75. PubMed ID: 24423612
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures.
    Cohen JR; Resnick DZ; Niewiadomski P; Dong H; Liau LM; Waschek JA
    BMC Cancer; 2010 Dec; 10():676. PubMed ID: 21143927
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The Hedgehog signal transduction network.
    Robbins DJ; Fei DL; Riobo NA
    Sci Signal; 2012 Oct; 5(246):re6. PubMed ID: 23074268
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.
    Chenna V; Hu C; Pramanik D; Aftab BT; Karikari C; Campbell NR; Hong SM; Zhao M; Rudek MA; Khan SR; Rudin CM; Maitra A
    Mol Cancer Ther; 2012 Jan; 11(1):165-73. PubMed ID: 22027695
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins.
    Polizio AH; Chinchilla P; Chen X; Manning DR; Riobo NA
    Sci Signal; 2011 Nov; 4(200):pt7. PubMed ID: 22114142
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Hedgehog signaling is a novel therapeutic target in tamoxifen-resistant breast cancer aberrantly activated by PI3K/AKT pathway.
    Ramaswamy B; Lu Y; Teng KY; Nuovo G; Li X; Shapiro CL; Majumder S
    Cancer Res; 2012 Oct; 72(19):5048-59. PubMed ID: 22875023
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.
    Peluso MO; Campbell VT; Harari JA; Tibbitts TT; Proctor JL; Whitebread N; Conley JM; White KF; Kutok JL; Read MA; McGovern K; Faia KL
    PLoS One; 2014; 9(3):e90534. PubMed ID: 24608250
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Identification of Nedd4 as a novel regulator in Hedgehog signaling.
    Luo QF; Chen W; Zhang ST
    Chin Med J (Engl); 2012 Nov; 125(21):3851-5. PubMed ID: 23106887
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Inhibition of Pancreatic Cancer Cell-Induced Paracrine Hedgehog Signaling by Liver X Receptor Agonists and Oxy16, a Naturally Occurring Oxysterol.
    Wang F; Stappenbeck F; Matsui W; Parhami F
    J Cell Biochem; 2017 Mar; 118(3):499-509. PubMed ID: 27490478
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity.
    Yang J; Huang W; Tan W
    Molecules; 2016 Oct; 21(10):. PubMed ID: 27754442
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Arhgap36-dependent activation of Gli transcription factors.
    Rack PG; Ni J; Payumo AY; Nguyen V; Crapster JA; Hovestadt V; Kool M; Jones DT; Mich JK; Firestone AJ; Pfister SM; Cho YJ; Chen JK
    Proc Natl Acad Sci U S A; 2014 Jul; 111(30):11061-6. PubMed ID: 25024229
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth.
    Wang J; Peng Y; Liu Y; Yang J; Ding N; Tan W
    BMC Cancer; 2015 Aug; 15():595. PubMed ID: 26296751
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Gli as a novel therapeutic target in malignant pleural mesothelioma.
    Li H; Lui N; Cheng T; Tseng HH; Yue D; Giroux-Leprieur E; Do HT; Sheng Q; Jin JQ; Luh TW; Jablons DM; He B
    PLoS One; 2013; 8(3):e57346. PubMed ID: 23483902
    [TBL] [Abstract][Full Text] [Related]  

  • 39. B13, a well-tolerated inhibitor of hedgehog pathway, exhibited potent anti-tumor effects against colorectal carcinoma in vitro and in vivo.
    Wu H; Zhang L; Chen B; Ou B; Xu J; Tian N; Yang D; Ai Y; Chen Q; Quan D; Zhang T; Lv L; Tian Y; Zhang J; Wu S
    Bioorg Chem; 2023 Jun; 135():106488. PubMed ID: 36989734
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.
    Chen Y; Sasai N; Ma G; Yue T; Jia J; Briscoe J; Jiang J
    PLoS Biol; 2011 Jun; 9(6):e1001083. PubMed ID: 21695114
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.