BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 25001283)

  • 1. Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
    Hung CM; Calejman CM; Sanchez-Gurmaches J; Li H; Clish CB; Hettmer S; Wagers AJ; Guertin DA
    Cell Rep; 2014 Jul; 8(1):256-71. PubMed ID: 25001283
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Brown fat organogenesis and maintenance requires AKT1 and AKT2.
    Sanchez-Gurmaches J; Martinez Calejman C; Jung SM; Li H; Guertin DA
    Mol Metab; 2019 May; 23():60-74. PubMed ID: 30833219
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
    Tang Y; Wallace M; Sanchez-Gurmaches J; Hsiao WY; Li H; Lee PL; Vernia S; Metallo CM; Guertin DA
    Nat Commun; 2016 Apr; 7():11365. PubMed ID: 27098609
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).
    Olson DH; Burrill JS; Kuzmicic J; Hahn WS; Park JM; Kim DH; Bernlohr DA
    Biochem Biophys Res Commun; 2017 Nov; 493(3):1311-1317. PubMed ID: 28986255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTORC2 regulates mechanically induced cytoskeletal reorganization and lineage selection in marrow-derived mesenchymal stem cells.
    Sen B; Xie Z; Case N; Thompson WR; Uzer G; Styner M; Rubin J
    J Bone Miner Res; 2014 Jan; 29(1):78-89. PubMed ID: 23821483
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
    Shu L; Houghton PJ
    Mol Cell Biol; 2009 Sep; 29(17):4691-700. PubMed ID: 19564418
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adipocyte lineages: tracing back the origins of fat.
    Sanchez-Gurmaches J; Guertin DA
    Biochim Biophys Acta; 2014 Mar; 1842(3):340-51. PubMed ID: 23747579
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells
    Zheng B; Wang J; Tang L; Tan C; Zhao Z; Xiao Y; Ge R; Zhu D
    Int J Biol Sci; 2017; 13(1):110-121. PubMed ID: 28123351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.
    Chen Z; Kang X; Wang L; Dong H; Wang C; Xiong Z; Zhao W; Jia C; Lin J; Zhang W; Yuan W; Zhong M; Du H; Bai X
    J Biol Chem; 2015 Mar; 290(10):6387-96. PubMed ID: 25564616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
    Jung SM; Hung CM; Hildebrand SR; Sanchez-Gurmaches J; Martinez-Pastor B; Gengatharan JM; Wallace M; Mukhopadhyay D; Martinez Calejman C; Luciano AK; Hsiao WY; Tang Y; Li H; Daniels DL; Mostoslavsky R; Metallo CM; Guertin DA
    Mol Cell; 2019 Aug; 75(4):807-822.e8. PubMed ID: 31442424
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice.
    Tripathy S; Jump DB
    J Lipid Res; 2013 Jan; 54(1):71-84. PubMed ID: 23099444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
    J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
    Lamming DW; Mihaylova MM; Katajisto P; Baar EL; Yilmaz OH; Hutchins A; Gultekin Y; Gaither R; Sabatini DM
    Aging Cell; 2014 Oct; 13(5):911-7. PubMed ID: 25059582
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling.
    Entwisle SW; Martinez Calejman C; Valente AS; Lawrence RT; Hung CM; Guertin DA; Villén J
    Mol Cell Proteomics; 2020 Jul; 19(7):1104-1119. PubMed ID: 32234964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
    Lee D; Sykes SM; Kalaitzidis D; Lane AA; Kfoury Y; Raaijmakers MH; Wang YH; Armstrong SA; Scadden DT
    Stem Cell Reports; 2014 Nov; 3(5):832-40. PubMed ID: 25418727
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
    Singh BK; Sinha RA; Zhou J; Tripathi M; Ohba K; Wang ME; Astapova I; Ghosh S; Hollenberg AN; Gauthier K; Yen PM
    J Biol Chem; 2016 Jan; 291(1):198-214. PubMed ID: 26453307
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation.
    Yao Y; Suraokar M; Darnay BG; Hollier BG; Shaiken TE; Asano T; Chen CH; Chang BH; Lu Y; Mills GB; Sarbassov D; Mani SA; Abbruzzese JL; Reddy SA
    Sci Signal; 2013 Jan; 6(257):ra2. PubMed ID: 23300339
    [TBL] [Abstract][Full Text] [Related]  

  • 19. mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes.
    Eid S; Boutary S; Braych K; Sabra R; Massaad C; Hamdy A; Rashid A; Moodad S; Block K; Gorin Y; Abboud HE; Eid AA
    Antioxid Redox Signal; 2016 Nov; 25(13):703-719. PubMed ID: 27393154
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.