118 related articles for article (PubMed ID: 25001485)
1. Synthetic studies on mitotic kinesin Eg5 inhibitors: synthesis and structure-activity relationships of novel 2,4,5-substituted-1,3,4-thiadiazoline derivatives.
Yamamoto J; Amishiro N; Kato K; Ohta Y; Ino Y; Araki M; Tsujita T; Okamoto S; Takahashi T; Kusaka H; Akinaga S; Yamashita Y; Nakai R; Murakata C
Bioorg Med Chem Lett; 2014 Aug; 24(16):3961-3. PubMed ID: 25001485
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationships and molecular docking of novel dihydropyrimidine-based mitotic Eg5 inhibitors.
Prokopcová H; Dallinger D; Uray G; Kaan HY; Ulaganathan V; Kozielski F; Laggner C; Kappe CO
ChemMedChem; 2010 Oct; 5(10):1760-9. PubMed ID: 20737530
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and pharmacological screening of a large library of 1,3,4-thiadiazolines as innovative therapeutic tools for the treatment of prostate cancer and melanoma.
De Monte C; Carradori S; Secci D; D'Ascenzio M; Guglielmi P; Mollica A; Morrone S; Scarpa S; Aglianò AM; Giantulli S; Silvestri I
Eur J Med Chem; 2015 Nov; 105():245-62. PubMed ID: 26498571
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, biological evaluation and molecular docking studies of flavone and isoflavone derivatives as a novel class of KSP (kinesin spindle protein) inhibitors.
Dong JJ; Li QS; Liu ZP; Wang SF; Zhao MY; Yang YH; Wang XM; Zhu HL
Eur J Med Chem; 2013; 70():427-33. PubMed ID: 24184776
[TBL] [Abstract][Full Text] [Related]
5. New chemical tools for investigating human mitotic kinesin Eg5.
Klein E; DeBonis S; Thiede B; Skoufias DA; Kozielski F; Lebeau L
Bioorg Med Chem; 2007 Oct; 15(19):6474-88. PubMed ID: 17587586
[TBL] [Abstract][Full Text] [Related]
6. Dihydropyrazole and dihydropyrrole structures based design of Kif15 inhibitors as novel therapeutic agents for cancer.
Sebastian J
Comput Biol Chem; 2017 Jun; 68():164-174. PubMed ID: 28355588
[TBL] [Abstract][Full Text] [Related]
7. Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5.
Khathi SP; Chandrasekaran B; Karunanidhi S; Tham CL; Kozielski F; Sayyad N; Karpoormath R
Bioorg Med Chem Lett; 2018 Sep; 28(17):2930-2938. PubMed ID: 30055887
[TBL] [Abstract][Full Text] [Related]
8. Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes.
Dumas ME; Chen GY; Kendrick ND; Xu G; Larsen SD; Jana S; Waterson AG; Bauer JA; Hancock W; Sulikowski GA; Ohi R
Bioorg Med Chem Lett; 2019 Jan; 29(2):148-154. PubMed ID: 30528696
[TBL] [Abstract][Full Text] [Related]
9. Morelloflavone as a novel inhibitor of mitotic kinesin Eg5.
Ogunwa TH; Taii K; Sadakane K; Kawata Y; Maruta S; Miyanishi T
J Biochem; 2019 Aug; 166(2):129-137. PubMed ID: 30785183
[TBL] [Abstract][Full Text] [Related]
10. Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.
Abualhasan MN; Good JA; Wittayanarakul K; Anthony NG; Berretta G; Rath O; Kozielski F; Sutcliffe OB; Mackay SP
Eur J Med Chem; 2012 Aug; 54():483-98. PubMed ID: 22749640
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of 4-thiazolidinone analogs as potent in vitro anti-urease agents.
Rahim F; Zaman K; Ullah H; Taha M; Wadood A; Javed MT; Rehman W; Ashraf M; Uddin R; Uddin I; Asghar H; Khan AA; Khan KM
Bioorg Chem; 2015 Dec; 63():123-31. PubMed ID: 26520885
[TBL] [Abstract][Full Text] [Related]
12. Structural insights into a unique inhibitor binding pocket in kinesin spindle protein.
Ulaganathan V; Talapatra SK; Rath O; Pannifer A; Hackney DD; Kozielski F
J Am Chem Soc; 2013 Feb; 135(6):2263-72. PubMed ID: 23305346
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.
Ogo N; Oishi S; Matsuno K; Sawada J; Fujii N; Asai A
Bioorg Med Chem Lett; 2007 Jul; 17(14):3921-4. PubMed ID: 17524640
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of N-(1-(6-acetamido-5-phenylpyrimidin-4-yl) piperidin-3-yl) amide derivatives as potential inhibitors for mitotic kinesin spindle protein.
Muthuraja P; Himesh M; Prakash S; Venkatasubramanian U; Manisankar P
Eur J Med Chem; 2018 Mar; 148():106-115. PubMed ID: 29454915
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.
Talapatra SK; Tham CL; Guglielmi P; Cirilli R; Chandrasekaran B; Karpoormath R; Carradori S; Kozielski F
Eur J Med Chem; 2018 Aug; 156():641-651. PubMed ID: 30031975
[TBL] [Abstract][Full Text] [Related]
16. The discovery of tetrahydro-beta-carbolines as inhibitors of the kinesin Eg5.
Barsanti PA; Wang W; Ni ZJ; Duhl D; Brammeier N; Martin E; Bussiere D; Walter AO
Bioorg Med Chem Lett; 2010 Jan; 20(1):157-60. PubMed ID: 19945875
[TBL] [Abstract][Full Text] [Related]
17. Kinesin Eg5 Targeting Inhibitors as a New Strategy for Gastric Adenocarcinoma Treatment.
Marconi GD; Carradori S; Ricci A; Guglielmi P; Cataldi A; Zara S
Molecules; 2019 Oct; 24(21):. PubMed ID: 31683688
[TBL] [Abstract][Full Text] [Related]
18. Structure-activity relationship of pyrazolo pyrimidine derivatives as inhibitors of mitotic kinesin Eg5 and anticancer agents.
Muthuraja P; Veeramani V; Prakash S; Himesh M; Venkatasubramanian U; Manisankar P
Bioorg Chem; 2019 Mar; 84():493-504. PubMed ID: 30594885
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.
Debonis S; Skoufias DA; Indorato RL; Liger F; Marquet B; Laggner C; Joseph B; Kozielski F
J Med Chem; 2008 Mar; 51(5):1115-25. PubMed ID: 18266314
[TBL] [Abstract][Full Text] [Related]
20. Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents.
Maccari R; Vitale RM; Ottanà R; Rocchiccioli M; Marrazzo A; Cardile V; Graziano AC; Amodeo P; Mura U; Del Corso A
Eur J Med Chem; 2014 Jun; 81():1-14. PubMed ID: 24819954
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
