These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

565 related articles for article (PubMed ID: 25002183)

  • 1. The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism.
    Zhang CS; Jiang B; Li M; Zhu M; Peng Y; Zhang YL; Wu YQ; Li TY; Liang Y; Lu Z; Lian G; Liu Q; Guo H; Yin Z; Ye Z; Han J; Wu JW; Yin H; Lin SY; Lin SC
    Cell Metab; 2014 Sep; 20(3):526-40. PubMed ID: 25002183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determining AMPK Activation via the Lysosomal v-ATPase-Ragulator-AXIN/LKB1 Axis.
    Zhang CS; Li M; Zong Y; Lin SC
    Methods Mol Biol; 2018; 1732():393-411. PubMed ID: 29480489
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methods to Study Lysosomal AMPK Activation.
    Zhang CS; Li M; Lin SC
    Methods Enzymol; 2017; 587():465-480. PubMed ID: 28253973
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation.
    Zhang YL; Guo H; Zhang CS; Lin SY; Yin Z; Peng Y; Luo H; Shi Y; Lian G; Zhang C; Li M; Ye Z; Ye J; Han J; Li P; Wu JW; Lin SC
    Cell Metab; 2013 Oct; 18(4):546-55. PubMed ID: 24093678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism. Differential regulation of mTORC1 by leucine and glutamine.
    Jewell JL; Kim YC; Russell RC; Yu FX; Park HW; Plouffe SW; Tagliabracci VS; Guan KL
    Science; 2015 Jan; 347(6218):194-8. PubMed ID: 25567907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
    Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
    Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino Acid Availability Modulates Vacuolar H+-ATPase Assembly.
    Stransky LA; Forgac M
    J Biol Chem; 2015 Nov; 290(45):27360-27369. PubMed ID: 26378229
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.
    Milkereit R; Persaud A; Vanoaica L; Guetg A; Verrey F; Rotin D
    Nat Commun; 2015 May; 6():7250. PubMed ID: 25998567
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase.
    Zoncu R; Bar-Peled L; Efeyan A; Wang S; Sancak Y; Sabatini DM
    Science; 2011 Nov; 334(6056):678-83. PubMed ID: 22053050
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MicroRNA-451 regulates AMPK/mTORC1 signaling and fascin1 expression in HT-29 colorectal cancer.
    Chen MB; Wei MX; Han JY; Wu XY; Li C; Wang J; Shen W; Lu PH
    Cell Signal; 2014 Jan; 26(1):102-9. PubMed ID: 23899558
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
    Zhang CS; Hawley SA; Zong Y; Li M; Wang Z; Gray A; Ma T; Cui J; Feng JW; Zhu M; Wu YQ; Li TY; Ye Z; Lin SY; Yin H; Piao HL; Hardie DG; Lin SC
    Nature; 2017 Aug; 548(7665):112-116. PubMed ID: 28723898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy.
    Meo-Evoli N; Almacellas E; Massucci FA; Gentilella A; Ambrosio S; Kozma SC; Thomas G; Tauler A
    Oncotarget; 2015 Sep; 6(29):28057-70. PubMed ID: 26356814
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p18/LAMTOR1: a late endosome/lysosome-specific anchor protein for the mTORC1/MAPK signaling pathway.
    Nada S; Mori S; Takahashi Y; Okada M
    Methods Enzymol; 2014; 535():249-63. PubMed ID: 24377928
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
    Bar-Peled L; Schweitzer LD; Zoncu R; Sabatini DM
    Cell; 2012 Sep; 150(6):1196-208. PubMed ID: 22980980
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR-v-ATPase axis.
    Wang S; Schianchi F; Neumann D; Wong LY; Sun A; van Nieuwenhoven FA; Zeegers MP; Strzelecka A; Col U; Glatz JFC; Nabben M; Luiken JJFP
    Mol Metab; 2021 Nov; 53():101293. PubMed ID: 34265467
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucose starvation increases V-ATPase assembly and activity in mammalian cells through AMP kinase and phosphatidylinositide 3-kinase/Akt signaling.
    McGuire CM; Forgac M
    J Biol Chem; 2018 Jun; 293(23):9113-9123. PubMed ID: 29540478
    [TBL] [Abstract][Full Text] [Related]  

  • 17. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms.
    Nwadike C; Williamson LE; Gallagher LE; Guan JL; Chan EYW
    Mol Cell Biol; 2018 May; 38(10):. PubMed ID: 29507183
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
    Jung J; Genau HM; Behrends C
    Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Orexin/hypocretin activates mTOR complex 1 (mTORC1) via an Erk/Akt-independent and calcium-stimulated lysosome v-ATPase pathway.
    Wang Z; Liu S; Kakizaki M; Hirose Y; Ishikawa Y; Funato H; Yanagisawa M; Yu Y; Liu Q
    J Biol Chem; 2014 Nov; 289(46):31950-31959. PubMed ID: 25278019
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The lysosome: a crucial hub for AMPK and mTORC1 signalling.
    Carroll B; Dunlop EA
    Biochem J; 2017 Apr; 474(9):1453-1466. PubMed ID: 28408430
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.