These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 25003665)

  • 1. Phase I study and preclinical efficacy evaluation of the mTOR inhibitor sirolimus plus gemcitabine in patients with advanced solid tumours.
    Martin-Liberal J; Gil-Martín M; Sáinz-Jaspeado M; Gonzalo N; Rigo R; Colom H; Muñoz C; Tirado OM; García del Muro X
    Br J Cancer; 2014 Aug; 111(5):858-65. PubMed ID: 25003665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Safety, tolerability and antitumour activity of LY2780301 (p70S6K/AKT inhibitor) in combination with gemcitabine in molecularly selected patients with advanced or metastatic cancer: a phase IB dose escalation study.
    Angevin E; Cassier PA; Italiano A; Gonçalves A; Gazzah A; Terret C; Toulmonde M; Gravis G; Varga A; Parlavecchio C; Paci A; Poinsignon V; Soria JC; Drubay D; Hollebecque A
    Eur J Cancer; 2017 Sep; 83():194-202. PubMed ID: 28750271
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sirolimus plus gemcitabine: a new therapeutic combination for resistant sarcomas?
    Martin-Liberal J; Tirado OM; García del Muro X
    Expert Rev Anticancer Ther; 2015 Mar; 15(3):257-9. PubMed ID: 25586480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy.
    Park H; Garrido-Laguna I; Naing A; Fu S; Falchook GS; Piha-Paul SA; Wheler JJ; Hong DS; Tsimberidou AM; Subbiah V; Zinner RG; Kaseb AO; Patel S; Fanale MA; Velez-Bravo VM; Meric-Bernstam F; Kurzrock R; Janku F
    Oncotarget; 2016 Oct; 7(41):67521-67531. PubMed ID: 27589687
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combination of antiangiogenic therapy using the mTOR-inhibitor everolimus and low-dose chemotherapy for locally advanced and/or metastatic pancreatic cancer: a dose-finding study.
    Joka M; Boeck S; Zech CJ; Seufferlein T; Wichert Gv; Licht T; Krause A; Jauch KW; Heinemann V; Bruns CJ
    Anticancer Drugs; 2014 Oct; 25(9):1095-101. PubMed ID: 25029236
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.
    O'Reilly T; McSheehy PM; Wartmann M; Lassota P; Brandt R; Lane HA
    Anticancer Drugs; 2011 Jan; 22(1):58-78. PubMed ID: 20890178
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.
    Tabernero J; Rojo F; Calvo E; Burris H; Judson I; Hazell K; Martinelli E; Ramon y Cajal S; Jones S; Vidal L; Shand N; Macarulla T; Ramos FJ; Dimitrijevic S; Zoellner U; Tang P; Stumm M; Lane HA; Lebwohl D; Baselga J
    J Clin Oncol; 2008 Apr; 26(10):1603-10. PubMed ID: 18332469
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies.
    Deenen MJ; Klümpen HJ; Richel DJ; Sparidans RW; Weterman MJ; Beijnen JH; Schellens JH; Wilmink JW
    Invest New Drugs; 2012 Aug; 30(4):1557-65. PubMed ID: 21809026
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gemcitabine and Selected mTOR Inhibitors in Uterine Sarcomas and Carcinosarcoma Cells- an Isobolographic Analysis.
    Bobiński M; Okła K; Łuszczki J; Bednarek W; Wawruszak A; Moreno-Bueno G; Garcia-Sanz P; Dmoszyńska-Graniczka M; Tarkowski R; Kotarski J
    Int J Med Sci; 2020; 17(18):2987-2997. PubMed ID: 33173419
    [No Abstract]   [Full Text] [Related]  

  • 10. Phase 1b study of the mammalian target of rapamycin inhibitor sirolimus in combination with nanoparticle albumin-bound paclitaxel in patients with advanced solid tumors.
    Abu-Khalaf MM; Baumgart MA; Gettinger SN; Doddamane I; Tuck DP; Hou S; Chen N; Sullivan C; Lezon-Geyda K; Zelterman D; Hatzis C; Deshpande H; Digiovanna MP; Azodi M; Schwartz PE; Harris LN
    Cancer; 2015 Jun; 121(11):1817-26. PubMed ID: 25649370
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PR-104 a bioreductive pre-prodrug combined with gemcitabine or docetaxel in a phase Ib study of patients with advanced solid tumours.
    McKeage MJ; Jameson MB; Ramanathan RK; Rajendran J; Gu Y; Wilson WR; Melink TJ; Tchekmedyian NS
    BMC Cancer; 2012 Oct; 12():496. PubMed ID: 23098625
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of the pharmacodynamic activity of the mTOR inhibitor ridaforolimus (AP23573, MK-8669) in a phase 1 clinical trial.
    Berk L; Mita MM; Kreisberg J; Bedrosian CL; Tolcher AW; Clackson T; Rivera VM
    Cancer Chemother Pharmacol; 2012 May; 69(5):1369-77. PubMed ID: 22231376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase I, dose-escalation study of AZD7762 alone and in combination with gemcitabine in Japanese patients with advanced solid tumours.
    Seto T; Esaki T; Hirai F; Arita S; Nosaki K; Makiyama A; Kometani T; Fujimoto C; Hamatake M; Takeoka H; Agbo F; Shi X
    Cancer Chemother Pharmacol; 2013 Sep; 72(3):619-27. PubMed ID: 23892959
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phase I dose escalation study of gemcitabine and paclitaxel plus colony-stimulating factors in previously treated patients with advanced breast and ovarian cancer.
    Iaffaioli RV; Tortoriello A; Santangelo M; Turitto G; Libutti M; Benassai G; Frattolillo A; Ciccarelli PD; De Rosa P; Crovella F; Carbone I; Barbarisi A
    Clin Oncol (R Coll Radiol); 2000; 12(4):251-5. PubMed ID: 11005695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma.
    Schuetze SM; Zhao L; Chugh R; Thomas DG; Lucas DR; Metko G; Zalupski MM; Baker LH
    Eur J Cancer; 2012 Jun; 48(9):1347-53. PubMed ID: 22525224
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase I study of Rigosertib, an inhibitor of the phosphatidylinositol 3-kinase and Polo-like kinase 1 pathways, combined with gemcitabine in patients with solid tumors and pancreatic cancer.
    Ma WW; Messersmith WA; Dy GK; Weekes CD; Whitworth A; Ren C; Maniar M; Wilhelm F; Eckhardt SG; Adjei AA; Jimeno A
    Clin Cancer Res; 2012 Apr; 18(7):2048-55. PubMed ID: 22338014
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A phase I trial of the mTOR inhibitor temsirolimus in combination with capecitabine in patients with advanced malignancies.
    Trivedi ND; Armstrong S; Wang H; Hartley M; Deeken J; Ruth He A; Subramaniam D; Melville H; Albanese C; Marshall JL; Hwang J; Pishvaian MJ
    Cancer Med; 2021 Mar; 10(6):1944-1954. PubMed ID: 33638305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma.
    Rangwala R; Chang YC; Hu J; Algazy KM; Evans TL; Fecher LA; Schuchter LM; Torigian DA; Panosian JT; Troxel AB; Tan KS; Heitjan DF; DeMichele AM; Vaughn DJ; Redlinger M; Alavi A; Kaiser J; Pontiggia L; Davis LE; O'Dwyer PJ; Amaravadi RK
    Autophagy; 2014 Aug; 10(8):1391-402. PubMed ID: 24991838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A phase I dose-escalation study to evaluate safety and tolerability of sorafenib combined with sirolimus in patients with advanced solid cancer.
    Desar IM; Timmer-Bonte JN; Burger DM; van der Graaf WT; van Herpen CM
    Br J Cancer; 2010 Nov; 103(11):1637-43. PubMed ID: 21045832
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Phase I/II Investigation of Safety and Efficacy of Nivolumab and
    Gordon EM; Angel NL; Omelchenko N; Chua-Alcala VS; Moradkhani A; Quon D; Wong S
    Anticancer Res; 2023 May; 43(5):1993-2002. PubMed ID: 37097693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.