BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 25003995)

  • 81. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
    Thapa P; Kadayat TM; Park S; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Bioorg Chem; 2016 Jun; 66():145-59. PubMed ID: 27174797
    [TBL] [Abstract][Full Text] [Related]  

  • 82. Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents.
    Martín-Encinas E; Rubiales G; Knudsen BR; Palacios F; Alonso C
    Bioorg Med Chem; 2021 Jun; 40():116177. PubMed ID: 33962152
    [TBL] [Abstract][Full Text] [Related]  

  • 83. Design and synthesis of novel 7-[(
    Song ZL; Yang GZ; Li JC; Liu YQ; Yang CJ; Goto M; Zhang ZJ; Morris-Natschke SL; Liu H; Lee KH
    Nat Prod Res; 2020 Jul; 34(14):2022-2029. PubMed ID: 30784310
    [TBL] [Abstract][Full Text] [Related]  

  • 84. Synthesis and biological evaluation of 1,5-naphthyridines as topoisomerase I inhibitors. A new family of antiproliferative agents.
    Alonso C; Fuertes M; González M; Rodríguez-Gascón A; Rubiales G; Palacios F
    Curr Top Med Chem; 2014; 14(23):2722-8. PubMed ID: 25515747
    [TBL] [Abstract][Full Text] [Related]  

  • 85. Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases.
    Khadka DB; Tran GH; Shin S; Nguyen HT; Cao HT; Zhao C; Jin Y; Van HT; Chau MV; Kwon Y; Le TN; Cho WJ
    Eur J Med Chem; 2015 Oct; 103():69-79. PubMed ID: 26334499
    [TBL] [Abstract][Full Text] [Related]  

  • 86. Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity.
    Dallavalle S; Ferrari A; Biasotti B; Merlini L; Penco S; Gallo G; Marzi M; Tinti MO; Martinelli R; Pisano C; Carminati P; Carenini N; Beretta G; Perego P; De Cesare M; Pratesi G; Zunino F
    J Med Chem; 2001 Sep; 44(20):3264-74. PubMed ID: 11563925
    [TBL] [Abstract][Full Text] [Related]  

  • 87. Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase I inhibitory properties.
    Lee CC; Chang DM; Huang KF; Chen CL; Chen TC; Lo Y; Guh JH; Huang HS
    Bioorg Med Chem; 2013 Nov; 21(22):7125-33. PubMed ID: 24094433
    [TBL] [Abstract][Full Text] [Related]  

  • 88. Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
    Park S; Thapa Magar TB; Kadayat TM; Lee HJ; Bist G; Shrestha A; Lee ES; Kwon Y
    Eur J Med Chem; 2017 Feb; 127():318-333. PubMed ID: 28068603
    [TBL] [Abstract][Full Text] [Related]  

  • 89. Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors.
    Kovvuri J; Nagaraju B; Nayak VL; Akunuri R; Rao MPN; Ajitha A; Nagesh N; Kamal A
    Eur J Med Chem; 2018 Jan; 143():1563-1577. PubMed ID: 29129513
    [TBL] [Abstract][Full Text] [Related]  

  • 90. Design, Synthesis and Cytotoxicity Evaluation of New 3, 5-Disubstituted-2-Thioxoimidazolidinones.
    Abdellatif KRA; Elbadawi MM; Elsaady MT; Abd El-Hafeez AA; Fujimura T; Kawamoto S; Khodair AI
    Anticancer Agents Med Chem; 2018; 18(4):573-582. PubMed ID: 29189182
    [TBL] [Abstract][Full Text] [Related]  

  • 91. Synthesis and docking studies of novel benzopyran-2-ones with anticancer activity.
    Ismail MM; Rateb HS; Hussein MM
    Eur J Med Chem; 2010 Sep; 45(9):3950-9. PubMed ID: 20580139
    [TBL] [Abstract][Full Text] [Related]  

  • 92. Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold.
    Fukuda T; Nanjo Y; Fujimoto M; Yoshida K; Natsui Y; Ishibashi F; Okazaki F; To H; Iwao M
    Bioorg Med Chem; 2019 Jan; 27(2):265-277. PubMed ID: 30553626
    [TBL] [Abstract][Full Text] [Related]  

  • 93. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
    Karki R; Jun KY; Kadayat TM; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Eur J Med Chem; 2016 May; 113():228-45. PubMed ID: 26945111
    [TBL] [Abstract][Full Text] [Related]  

  • 94. Synthesis, topoisomerase I inhibitory activity, and in vivo evaluation of 11-azacamptothecin analogs.
    Uehling DE; Nanthakumar SS; Croom D; Emerson DL; Leitner PP; Luzzio MJ; McIntyre G; Morton B; Profeta S; Sisco J
    J Med Chem; 1995 Mar; 38(7):1106-18. PubMed ID: 7707314
    [TBL] [Abstract][Full Text] [Related]  

  • 95. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents.
    Zhang XR; Wang HW; Tang WL; Zhang Y; Yang H; Hu DX; Ravji A; Marchand C; Kiselev E; Ofori-Atta K; Agama K; Pommier Y; An LK
    J Med Chem; 2018 Nov; 61(22):9908-9930. PubMed ID: 30336023
    [TBL] [Abstract][Full Text] [Related]  

  • 96. Novel Hybrid Molecules on the Basis of Steroids and (5Z,9Z)-Tetradeca-5,9-dienoic Acid: Synthesis, Anti-Cancer Studies and Human Topoisomerase I Inhibitory Activity.
    D'yakonov VA; Dzhemileva LU; Tuktarova RA; Ishmukhametova SR; Yunusbaeva MM; Ramazanova IR; Dzhemilev UM
    Anticancer Agents Med Chem; 2017; 17(8):1126-1135. PubMed ID: 27928953
    [TBL] [Abstract][Full Text] [Related]  

  • 97. Copper-catalyzed three-component synthesis of aminonaphthoquinone-sulfonylamidine conjugates and in vitro evaluation of their antiproliferative activity.
    Suja TD; Divya KV; Naik LV; Ravi Kumar A; Kamal A
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2072-6. PubMed ID: 26948541
    [TBL] [Abstract][Full Text] [Related]  

  • 98. Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues.
    Tardy C; Facompré M; Laine W; Baldeyrou B; García-Gravalos D; Francesch A; Mateo C; Pastor A; Jiménez JA; Manzanares I; Cuevas C; Bailly C
    Bioorg Med Chem; 2004 Apr; 12(7):1697-712. PubMed ID: 15028262
    [TBL] [Abstract][Full Text] [Related]  

  • 99. Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs.
    Baechler SA; Fehr M; Habermeyer M; Hofmann A; Merz KH; Fiebig HH; Marko D; Eisenbrand G
    Bioorg Med Chem; 2013 Feb; 21(3):814-23. PubMed ID: 23266176
    [TBL] [Abstract][Full Text] [Related]  

  • 100. Hybrid topoisomerase I and HDAC inhibitors as dual action anticancer agents.
    Cincinelli R; Musso L; Artali R; Guglielmi MB; La Porta I; Melito C; Colelli F; Cardile F; Signorino G; Fucci A; Frusciante M; Pisano C; Dallavalle S
    PLoS One; 2018; 13(10):e0205018. PubMed ID: 30300374
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.